BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

622 related articles for article (PubMed ID: 23471911)

  • 1. Motor neurons and glia exhibit specific individualized responses to TDP-43 expression in a Drosophila model of amyotrophic lateral sclerosis.
    Estes PS; Daniel SG; McCallum AP; Boehringer AV; Sukhina AS; Zwick RA; Zarnescu DC
    Dis Model Mech; 2013 May; 6(3):721-33. PubMed ID: 23471911
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Pathological Modification of TDP-43 in Amyotrophic Lateral Sclerosis with SOD1 Mutations.
    Jeon GS; Shim YM; Lee DY; Kim JS; Kang M; Ahn SH; Shin JY; Geum D; Hong YH; Sung JJ
    Mol Neurobiol; 2019 Mar; 56(3):2007-2021. PubMed ID: 29982983
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Mutant TDP-43 within motor neurons drives disease onset but not progression in amyotrophic lateral sclerosis.
    Ditsworth D; Maldonado M; McAlonis-Downes M; Sun S; Seelman A; Drenner K; Arnold E; Ling SC; Pizzo D; Ravits J; Cleveland DW; Da Cruz S
    Acta Neuropathol; 2017 Jun; 133(6):907-922. PubMed ID: 28357566
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Drosophila TDP-43 dysfunction in glia and muscle cells cause cytological and behavioural phenotypes that characterize ALS and FTLD.
    Diaper DC; Adachi Y; Lazarou L; Greenstein M; Simoes FA; Di Domenico A; Solomon DA; Lowe S; Alsubaie R; Cheng D; Buckley S; Humphrey DM; Shaw CE; Hirth F
    Hum Mol Genet; 2013 Oct; 22(19):3883-93. PubMed ID: 23727833
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Motor neuron expression of the voltage-gated calcium channel cacophony restores locomotion defects in a Drosophila, TDP-43 loss of function model of ALS.
    Chang JC; Hazelett DJ; Stewart JA; Morton DB
    Brain Res; 2014 Oct; 1584():39-51. PubMed ID: 24275199
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Neuronal function and dysfunction of Drosophila dTDP.
    Lin MJ; Cheng CW; Shen CK
    PLoS One; 2011; 6(6):e20371. PubMed ID: 21673800
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Post-transcriptional Inhibition of Hsc70-4/HSPA8 Expression Leads to Synaptic Vesicle Cycling Defects in Multiple Models of ALS.
    Coyne AN; Lorenzini I; Chou CC; Torvund M; Rogers RS; Starr A; Zaepfel BL; Levy J; Johannesmeyer J; Schwartz JC; Nishimune H; Zinsmaier K; Rossoll W; Sattler R; Zarnescu DC
    Cell Rep; 2017 Oct; 21(1):110-125. PubMed ID: 28978466
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Senataxin mutations elicit motor neuron degeneration phenotypes and yield TDP-43 mislocalization in ALS4 mice and human patients.
    Bennett CL; Dastidar SG; Ling SC; Malik B; Ashe T; Wadhwa M; Miller DB; Lee C; Mitchell MB; van Es MA; Grunseich C; Chen Y; Sopher BL; Greensmith L; Cleveland DW; La Spada AR
    Acta Neuropathol; 2018 Sep; 136(3):425-443. PubMed ID: 29725819
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Neuronal over-expression of Oxr1 is protective against ALS-associated mutant TDP-43 mislocalisation in motor neurons and neuromuscular defects in vivo.
    Williamson MG; Finelli MJ; Sleigh JN; Reddington A; Gordon D; Talbot K; Davies KE; Oliver PL
    Hum Mol Genet; 2019 Nov; 28(21):3584-3599. PubMed ID: 31642482
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Single-copy expression of an amyotrophic lateral sclerosis-linked TDP-43 mutation (M337V) in BAC transgenic mice leads to altered stress granule dynamics and progressive motor dysfunction.
    Gordon D; Dafinca R; Scaber J; Alegre-Abarrategui J; Farrimond L; Scott C; Biggs D; Kent L; Oliver PL; Davies B; Ansorge O; Wade-Martins R; Talbot K
    Neurobiol Dis; 2019 Jan; 121():148-162. PubMed ID: 30290270
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The ALS disease protein TDP-43 is actively transported in motor neuron axons and regulates axon outgrowth.
    Fallini C; Bassell GJ; Rossoll W
    Hum Mol Genet; 2012 Aug; 21(16):3703-18. PubMed ID: 22641816
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Familial Amyotrophic Lateral Sclerosis-linked Mutations in Profilin 1 Exacerbate TDP-43-induced Degeneration in the Retina of Drosophila melanogaster through an Increase in the Cytoplasmic Localization of TDP-43.
    Matsukawa K; Hashimoto T; Matsumoto T; Ihara R; Chihara T; Miura M; Wakabayashi T; Iwatsubo T
    J Biol Chem; 2016 Nov; 291(45):23464-23476. PubMed ID: 27634045
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Lack of TNF-alpha receptor type 2 protects motor neurons in a cellular model of amyotrophic lateral sclerosis and in mutant SOD1 mice but does not affect disease progression.
    Tortarolo M; Vallarola A; Lidonnici D; Battaglia E; Gensano F; Spaltro G; Fiordaliso F; Corbelli A; Garetto S; Martini E; Pasetto L; Kallikourdis M; Bonetto V; Bendotti C
    J Neurochem; 2015 Oct; 135(1):109-24. PubMed ID: 25940956
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Evidence of multisystem disorder in whole-brain map of pathological TDP-43 in amyotrophic lateral sclerosis.
    Geser F; Brandmeir NJ; Kwong LK; Martinez-Lage M; Elman L; McCluskey L; Xie SX; Lee VM; Trojanowski JQ
    Arch Neurol; 2008 May; 65(5):636-41. PubMed ID: 18474740
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Ubiquilin modifies TDP-43 toxicity in a Drosophila model of amyotrophic lateral sclerosis (ALS).
    Hanson KA; Kim SH; Wassarman DA; Tibbetts RS
    J Biol Chem; 2010 Apr; 285(15):11068-72. PubMed ID: 20154090
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Comparative interactomics analysis of different ALS-associated proteins identifies converging molecular pathways.
    Blokhuis AM; Koppers M; Groen EJN; van den Heuvel DMA; Dini Modigliani S; Anink JJ; Fumoto K; van Diggelen F; Snelting A; Sodaar P; Verheijen BM; Demmers JAA; Veldink JH; Aronica E; Bozzoni I; den Hertog J; van den Berg LH; Pasterkamp RJ
    Acta Neuropathol; 2016 Aug; 132(2):175-196. PubMed ID: 27164932
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Mutant TDP-43 in motor neurons promotes the onset and progression of ALS in rats.
    Huang C; Tong J; Bi F; Zhou H; Xia XG
    J Clin Invest; 2012 Jan; 122(1):107-18. PubMed ID: 22156203
    [TBL] [Abstract][Full Text] [Related]  

  • 18. TDP-43 dysregulation and neuromuscular junction disruption in amyotrophic lateral sclerosis.
    Lépine S; Castellanos-Montiel MJ; Durcan TM
    Transl Neurodegener; 2022 Dec; 11(1):56. PubMed ID: 36575535
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Wild-type and A315T mutant TDP-43 exert differential neurotoxicity in a Drosophila model of ALS.
    Estes PS; Boehringer A; Zwick R; Tang JE; Grigsby B; Zarnescu DC
    Hum Mol Genet; 2011 Jun; 20(12):2308-21. PubMed ID: 21441568
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Retrotransposon activation contributes to neurodegeneration in a Drosophila TDP-43 model of ALS.
    Krug L; Chatterjee N; Borges-Monroy R; Hearn S; Liao WW; Morrill K; Prazak L; Rozhkov N; Theodorou D; Hammell M; Dubnau J
    PLoS Genet; 2017 Mar; 13(3):e1006635. PubMed ID: 28301478
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 32.