154 related articles for article (PubMed ID: 23472952)
1. Discovery of (R)-2-amino-6-borono-2-(2-(piperidin-1-yl)ethyl)hexanoic acid and congeners as highly potent inhibitors of human arginases I and II for treatment of myocardial reperfusion injury.
Van Zandt MC; Whitehouse DL; Golebiowski A; Ji MK; Zhang M; Beckett RP; Jagdmann GE; Ryder TR; Sheeler R; Andreoli M; Conway B; Mahboubi K; D'Angelo G; Mitschler A; Cousido-Siah A; Ruiz FX; Howard EI; Podjarny AD; Schroeter H
J Med Chem; 2013 Mar; 56(6):2568-80. PubMed ID: 23472952
[TBL] [Abstract][Full Text] [Related]
2. Synthesis of quaternary α-amino acid-based arginase inhibitors via the Ugi reaction.
Golebiowski A; Whitehouse D; Beckett RP; Van Zandt M; Ji MK; Ryder TR; Jagdmann E; Andreoli M; Lee Y; Sheeler R; Conway B; Olczak J; Mazur M; Czestkowski W; Piotrowska W; Cousido-Siah A; Ruiz FX; Mitschler A; Podjarny A; Schroeter H
Bioorg Med Chem Lett; 2013 Sep; 23(17):4837-41. PubMed ID: 23886684
[TBL] [Abstract][Full Text] [Related]
3. Synthesis and evaluation of new omega-borono-alpha-amino acids as rat liver arginase inhibitors.
Busnel O; Carreaux F; Carboni B; Pethe S; Goff SV; Mansuy D; Boucher JL
Bioorg Med Chem; 2005 Apr; 13(7):2373-9. PubMed ID: 15755639
[TBL] [Abstract][Full Text] [Related]
4. Discovery of
Van Zandt MC; Jagdmann GE; Whitehouse DL; Ji M; Savoy J; Potapova O; Cousido-Siah A; Mitschler A; Howard EI; Pyle AM; Podjarny AD
J Med Chem; 2019 Sep; 62(17):8164-8177. PubMed ID: 31408339
[TBL] [Abstract][Full Text] [Related]
5. 2-Substituted-2-amino-6-boronohexanoic acids as arginase inhibitors.
Golebiowski A; Paul Beckett R; Van Zandt M; Ji MK; Whitehouse D; Ryder TR; Jagdmann E; Andreoli M; Mazur A; Padmanilayam M; Cousido-Siah A; Mitschler A; Ruiz FX; Podjarny A; Schroeter H
Bioorg Med Chem Lett; 2013 Apr; 23(7):2027-30. PubMed ID: 23453840
[TBL] [Abstract][Full Text] [Related]
6. Binding of α,α-disubstituted amino acids to arginase suggests new avenues for inhibitor design.
Ilies M; Di Costanzo L; Dowling DP; Thorn KJ; Christianson DW
J Med Chem; 2011 Aug; 54(15):5432-43. PubMed ID: 21728378
[TBL] [Abstract][Full Text] [Related]
7. Crystal structures of Leishmania mexicana arginase complexed with α,α-disubstituted boronic amino-acid inhibitors.
Hai Y; Christianson DW
Acta Crystallogr F Struct Biol Commun; 2016 Apr; 72(Pt 4):300-6. PubMed ID: 27050264
[TBL] [Abstract][Full Text] [Related]
8. Arginase-boronic acid complex highlights a physiological role in erectile function.
Cox JD; Kim NN; Traish AM; Christianson DW
Nat Struct Biol; 1999 Nov; 6(11):1043-7. PubMed ID: 10542097
[TBL] [Abstract][Full Text] [Related]
9. Insights into the Structural Requirements of 2(S)-Amino-6-Boronohexanoic Acid Derivatives as Arginase I Inhibitors: 3D-QSAR, Docking, and Interaction Fingerprint Studies.
Velázquez-Libera JL; Navarro-Retamal C; Caballero J
Int J Mol Sci; 2018 Sep; 19(10):. PubMed ID: 30274146
[TBL] [Abstract][Full Text] [Related]
10. Structural insights into Entamoeba histolytica arginase and structure-based identification of novel non-amino acid based inhibitors as potential antiamoebic molecules.
Malik A; Dalal V; Ankri S; Tomar S
FEBS J; 2019 Oct; 286(20):4135-4155. PubMed ID: 31199070
[TBL] [Abstract][Full Text] [Related]
11. Development of novel arginase inhibitors for therapy of endothelial dysfunction.
Steppan J; Nyhan D; Berkowitz DE
Front Immunol; 2013 Sep; 4():278. PubMed ID: 24062745
[TBL] [Abstract][Full Text] [Related]
12. Classical and slow-binding inhibitors of human type II arginase.
Colleluori DM; Ash DE
Biochemistry; 2001 Aug; 40(31):9356-62. PubMed ID: 11478904
[TBL] [Abstract][Full Text] [Related]
13. The Promise of Plant-Derived Substances as Inhibitors of Arginase.
Girard-Thernier C; Pham TN; Demougeot C
Mini Rev Med Chem; 2015; 15(10):798-808. PubMed ID: 25963565
[TBL] [Abstract][Full Text] [Related]
14. (S)-2-amino-6-nitrohexanoic acid binds to human arginase I through multiple nitro-metal coordination interactions in the binuclear manganese cluster.
Zakharian TY; Di Costanzo L; Christianson DW
J Am Chem Soc; 2008 Dec; 130(51):17254-5. PubMed ID: 19032027
[TBL] [Abstract][Full Text] [Related]
15. 2-aminoimidazole amino acids as inhibitors of the binuclear manganese metalloenzyme human arginase I.
Ilies M; Di Costanzo L; North ML; Scott JA; Christianson DW
J Med Chem; 2010 May; 53(10):4266-76. PubMed ID: 20441173
[TBL] [Abstract][Full Text] [Related]
16. Synthesis of a new trifluoromethylketone analogue of l-arginine and contrasting inhibitory activity against human arginase I and histone deacetylase 8.
Ilies M; Dowling DP; Lombardi PM; Christianson DW
Bioorg Med Chem Lett; 2011 Oct; 21(19):5854-8. PubMed ID: 21875805
[TBL] [Abstract][Full Text] [Related]
17. Discovery of a potent, orally bioavailable and highly selective human neuronal nitric oxide synthase (nNOS) inhibitor, N-(1-(piperidin-4-yl)indolin-5-yl)thiophene-2-carboximidamide as a pre-clinical development candidate for the treatment of migraine.
Annedi SC; Maddaford SP; Ramnauth J; Renton P; Rybak T; Silverman S; Rakhit S; Mladenova G; Dove P; Andrews JS; Zhang D; Porreca F
Eur J Med Chem; 2012 Sep; 55():94-107. PubMed ID: 22840695
[TBL] [Abstract][Full Text] [Related]
18. Arginase inhibition mediates cardioprotection during ischaemia-reperfusion.
Jung C; Gonon AT; Sjöquist PO; Lundberg JO; Pernow J
Cardiovasc Res; 2010 Jan; 85(1):147-54. PubMed ID: 19726439
[TBL] [Abstract][Full Text] [Related]
19. Design of amino acid sulfonamides as transition-state analogue inhibitors of arginase.
Cama E; Shin H; Christianson DW
J Am Chem Soc; 2003 Oct; 125(43):13052-7. PubMed ID: 14570477
[TBL] [Abstract][Full Text] [Related]
20. Design of amino acid aldehydes as transition-state analogue inhibitors of arginase.
Shin H; Cama E; Christianson DW
J Am Chem Soc; 2004 Aug; 126(33):10278-84. PubMed ID: 15315440
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
