BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

277 related articles for article (PubMed ID: 23478265)

  • 1. Human DEAD box helicase 3 couples IκB kinase ε to interferon regulatory factor 3 activation.
    Gu L; Fullam A; Brennan R; Schröder M
    Mol Cell Biol; 2013 May; 33(10):2004-15. PubMed ID: 23478265
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Viral targeting of DEAD box protein 3 reveals its role in TBK1/IKKepsilon-mediated IRF activation.
    Schröder M; Baran M; Bowie AG
    EMBO J; 2008 Aug; 27(15):2147-57. PubMed ID: 18636090
    [TBL] [Abstract][Full Text] [Related]  

  • 3. DDX3 directly facilitates IKKα activation and regulates downstream signalling pathways.
    Fullam A; Gu L; Höhn Y; Schröder M
    Biochem J; 2018 Nov; 475(22):3595-3607. PubMed ID: 30341167
    [TBL] [Abstract][Full Text] [Related]  

  • 4. DDX3 directly regulates TRAF3 ubiquitination and acts as a scaffold to co-ordinate assembly of signalling complexes downstream from MAVS.
    Gu L; Fullam A; McCormack N; Höhn Y; Schröder M
    Biochem J; 2017 Feb; 474(4):571-587. PubMed ID: 27980081
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Stimulation of DDX3 expression by ginsenoside Rg3 through the Akt/p53 pathway activates the innate immune response via TBK1/IKKε/IRF3 signalling.
    Choi YJ; Kang LJ; Lee SG
    Curr Med Chem; 2014; 21(8):1050-60. PubMed ID: 24180280
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Encephalomyocarditis virus 3C protease attenuates type I interferon production through disrupting the TANK-TBK1-IKKε-IRF3 complex.
    Huang L; Xiong T; Yu H; Zhang Q; Zhang K; Li C; Hu L; Zhang Y; Zhang L; Liu Q; Wang S; He X; Bu Z; Cai X; Cui S; Li J; Weng C
    Biochem J; 2017 Jun; 474(12):2051-2065. PubMed ID: 28487378
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Hepatitis B virus polymerase inhibits RIG-I- and Toll-like receptor 3-mediated beta interferon induction in human hepatocytes through interference with interferon regulatory factor 3 activation and dampening of the interaction between TBK1/IKKepsilon and DDX3.
    Yu S; Chen J; Wu M; Chen H; Kato N; Yuan Z
    J Gen Virol; 2010 Aug; 91(Pt 8):2080-2090. PubMed ID: 20375222
    [TBL] [Abstract][Full Text] [Related]  

  • 8. DEAD/H BOX 3 (DDX3) helicase binds the RIG-I adaptor IPS-1 to up-regulate IFN-beta-inducing potential.
    Oshiumi H; Sakai K; Matsumoto M; Seya T
    Eur J Immunol; 2010 Apr; 40(4):940-8. PubMed ID: 20127681
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Arenavirus nucleoprotein targets interferon regulatory factor-activating kinase IKKε.
    Pythoud C; Rodrigo WW; Pasqual G; Rothenberger S; Martínez-Sobrido L; de la Torre JC; Kunz S
    J Virol; 2012 Aug; 86(15):7728-38. PubMed ID: 22532683
    [TBL] [Abstract][Full Text] [Related]  

  • 10. DDX19 Inhibits Type I Interferon Production by Disrupting TBK1-IKKε-IRF3 Interactions and Promoting TBK1 and IKKε Degradation.
    Zhang K; Zhang Y; Xue J; Meng Q; Liu H; Bi C; Li C; Hu L; Yu H; Xiong T; Yang Y; Cui S; Bu Z; He X; Li J; Huang L; Weng C
    Cell Rep; 2019 Jan; 26(5):1258-1272.e4. PubMed ID: 30699353
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Middle East respiratory syndrome coronavirus ORF4b protein inhibits type I interferon production through both cytoplasmic and nuclear targets.
    Yang Y; Ye F; Zhu N; Wang W; Deng Y; Zhao Z; Tan W
    Sci Rep; 2015 Dec; 5():17554. PubMed ID: 26631542
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Peripheral B cells may serve as a reservoir for persistent hepatitis C virus infection.
    Ito M; Masumi A; Mochida K; Kukihara H; Moriishi K; Matsuura Y; Yamaguchi K; Mizuochi T
    J Innate Immun; 2010; 2(6):607-17. PubMed ID: 20714117
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Promoter organization of the interferon-A genes differentially affects virus-induced expression and responsiveness to TBK1 and IKKepsilon.
    Civas A; Génin P; Morin P; Lin R; Hiscott J
    J Biol Chem; 2006 Feb; 281(8):4856-66. PubMed ID: 16380379
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The RNA helicase DDX3 promotes IFNB transcription via enhancing IRF-3/p300 holocomplex binding to the IFNB promoter.
    Saikruang W; Ang Yan Ping L; Abe H; Kasumba DM; Kato H; Fujita T
    Sci Rep; 2022 Mar; 12(1):3967. PubMed ID: 35273248
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Vaccinia virus protein C6 is a virulence factor that binds TBK-1 adaptor proteins and inhibits activation of IRF3 and IRF7.
    Unterholzner L; Sumner RP; Baran M; Ren H; Mansur DS; Bourke NM; Randow F; Smith GL; Bowie AG
    PLoS Pathog; 2011 Sep; 7(9):e1002247. PubMed ID: 21931555
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Porcine Deltacoronavirus Accessory Protein NS7a Antagonizes IFN-β Production by Competing With TRAF3 and IRF3 for Binding to IKKε.
    Fang P; Fang L; Xia S; Ren J; Zhang J; Bai D; Zhou Y; Peng G; Zhao S; Xiao S
    Front Cell Infect Microbiol; 2020; 10():257. PubMed ID: 32656094
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Hepatitis C Virus Nonstructural Protein 5A Interacts with Immunomodulatory Kinase IKKε to Negatively Regulate Innate Antiviral Immunity.
    Kang SM; Park JY; Han HJ; Song BM; Tark D; Choi BS; Hwang SB
    Mol Cells; 2022 Oct; 45(10):702-717. PubMed ID: 35993162
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Induction of IRF-3 and IRF-7 phosphorylation following activation of the RIG-I pathway.
    Paz S; Sun Q; Nakhaei P; Romieu-Mourez R; Goubau D; Julkunen I; Lin R; Hiscott J
    Cell Mol Biol (Noisy-le-grand); 2006 May; 52(1):17-28. PubMed ID: 16914100
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Use of the pharmacological inhibitor BX795 to study the regulation and physiological roles of TBK1 and IkappaB kinase epsilon: a distinct upstream kinase mediates Ser-172 phosphorylation and activation.
    Clark K; Plater L; Peggie M; Cohen P
    J Biol Chem; 2009 May; 284(21):14136-46. PubMed ID: 19307177
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Involvement of TBK1 and IKKepsilon in lipopolysaccharide-induced activation of the interferon response in primary human macrophages.
    Solis M; Romieu-Mourez R; Goubau D; Grandvaux N; Mesplede T; Julkunen I; Nardin A; Salcedo M; Hiscott J
    Eur J Immunol; 2007 Feb; 37(2):528-39. PubMed ID: 17236232
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 14.