BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

275 related articles for article (PubMed ID: 23482611)

  • 1. A small molecule antagonist inhibits thyrotropin receptor antibody-induced orbital fibroblast functions involved in the pathogenesis of Graves ophthalmopathy.
    Turcu AF; Kumar S; Neumann S; Coenen M; Iyer S; Chiriboga P; Gershengorn MC; Bahn RS
    J Clin Endocrinol Metab; 2013 May; 98(5):2153-9. PubMed ID: 23482611
    [TBL] [Abstract][Full Text] [Related]  

  • 2. A drug-like antagonist inhibits thyrotropin receptor-mediated stimulation of cAMP production in Graves' orbital fibroblasts.
    Neumann S; Pope A; Geras-Raaka E; Raaka BM; Bahn RS; Gershengorn MC
    Thyroid; 2012 Aug; 22(8):839-43. PubMed ID: 22784331
    [TBL] [Abstract][Full Text] [Related]  

  • 3. PDGF enhances orbital fibroblast responses to TSHR stimulating autoantibodies in Graves' ophthalmopathy patients.
    van Steensel L; Hooijkaas H; Paridaens D; van den Bosch WA; Kuijpers RW; Drexhage HA; van Hagen PM; Dik WA
    J Clin Endocrinol Metab; 2012 Jun; 97(6):E944-53. PubMed ID: 22438231
    [TBL] [Abstract][Full Text] [Related]  

  • 4. A stimulatory thyrotropin receptor antibody enhances hyaluronic acid synthesis in graves' orbital fibroblasts: inhibition by an IGF-I receptor blocking antibody.
    Kumar S; Iyer S; Bauer H; Coenen M; Bahn RS
    J Clin Endocrinol Metab; 2012 May; 97(5):1681-7. PubMed ID: 22399503
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Thyrotropin receptor-stimulating Graves' disease immunoglobulins induce hyaluronan synthesis by differentiated orbital fibroblasts from patients with Graves' ophthalmopathy not only via cyclic adenosine monophosphate signaling pathways.
    van Zeijl CJ; Fliers E; van Koppen CJ; Surovtseva OV; de Gooyer ME; Mourits MP; Wiersinga WM; Miltenburg AM; Boelen A
    Thyroid; 2011 Feb; 21(2):169-76. PubMed ID: 20954819
    [TBL] [Abstract][Full Text] [Related]  

  • 6. A new small-molecule antagonist inhibits Graves' disease antibody activation of the TSH receptor.
    Neumann S; Eliseeva E; McCoy JG; Napolitano G; Giuliani C; Monaco F; Huang W; Gershengorn MC
    J Clin Endocrinol Metab; 2011 Feb; 96(2):548-54. PubMed ID: 21123444
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Effects of thyrotropin and thyrotropin-receptor-stimulating Graves' disease immunoglobulin G on cyclic adenosine monophosphate and hyaluronan production in nondifferentiated orbital fibroblasts of Graves' ophthalmopathy patients.
    van Zeijl CJ; Fliers E; van Koppen CJ; Surovtseva OV; de Gooyer ME; Mourits MP; Wiersinga WM; Miltenburg AM; Boelen A
    Thyroid; 2010 May; 20(5):535-44. PubMed ID: 20384487
    [TBL] [Abstract][Full Text] [Related]  

  • 8. A stimulatory TSH receptor antibody enhances adipogenesis via phosphoinositide 3-kinase activation in orbital preadipocytes from patients with Graves' ophthalmopathy.
    Kumar S; Nadeem S; Stan MN; Coenen M; Bahn RS
    J Mol Endocrinol; 2011 Jun; 46(3):155-63. PubMed ID: 21321093
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Inhibition of TSH/IGF-1 Receptor Crosstalk by Teprotumumab as a Treatment Modality of Thyroid Eye Disease.
    Krieger CC; Sui X; Kahaly GJ; Neumann S; Gershengorn MC
    J Clin Endocrinol Metab; 2022 Mar; 107(4):e1653-e1660. PubMed ID: 34788857
    [TBL] [Abstract][Full Text] [Related]  

  • 10. TSH/IGF-1 Receptor Cross Talk in Graves' Ophthalmopathy Pathogenesis.
    Krieger CC; Place RF; Bevilacqua C; Marcus-Samuels B; Abel BS; Skarulis MC; Kahaly GJ; Neumann S; Gershengorn MC
    J Clin Endocrinol Metab; 2016 Jun; 101(6):2340-7. PubMed ID: 27043163
    [TBL] [Abstract][Full Text] [Related]  

  • 11. A stimulatory thyrotropin receptor antibody (M22) and thyrotropin increase interleukin-6 expression and secretion in Graves' orbital preadipocyte fibroblasts.
    Kumar S; Schiefer R; Coenen MJ; Bahn RS
    Thyroid; 2010 Jan; 20(1):59-65. PubMed ID: 20017620
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Graves' Autoantibodies Exhibit Different Stimulating Activities in Cultures of Thyrocytes and Orbital Fibroblasts Not Reflected by Clinical Assays.
    Krieger CC; Kahaly GJ; Azam A; Klubo-Gwiezdzinska J; Neumann S; Gershengorn MC
    Thyroid; 2022 Jan; 32(1):90-96. PubMed ID: 34714162
    [No Abstract]   [Full Text] [Related]  

  • 13. Forkhead Transcription Factor FOXO1 Is Regulated by Both a Stimulatory Thyrotropin Receptor Antibody and Insulin-Like Growth Factor-1 in Orbital Fibroblasts from Patients with Graves' Ophthalmopathy.
    Kumar S; Coenen M; Iyer S; Bahn RS
    Thyroid; 2015 Oct; 25(10):1145-50. PubMed ID: 26213859
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Thyrotropin Receptor Antagonism by a Novel Small Molecule: Preclinical
    Kahaly GJ; Steiner L; van der Lee MMC; van Achterberg TAE; Arends RJ; Karstens WFJ; Weirauch T; Henseling J; Frommer L; Wolf J; George A
    Thyroid; 2023 Jun; 33(6):732-742. PubMed ID: 37016815
    [No Abstract]   [Full Text] [Related]  

  • 15. Bidirectional TSH and IGF-1 receptor cross talk mediates stimulation of hyaluronan secretion by Graves' disease immunoglobins.
    Krieger CC; Neumann S; Place RF; Marcus-Samuels B; Gershengorn MC
    J Clin Endocrinol Metab; 2015 Mar; 100(3):1071-7. PubMed ID: 25485727
    [TBL] [Abstract][Full Text] [Related]  

  • 16. A New Highly Thyrotropin Receptor-Selective Small-Molecule Antagonist with Potential for the Treatment of Graves' Orbitopathy.
    Marcinkowski P; Hoyer I; Specker E; Furkert J; Rutz C; Neuenschwander M; Sobottka S; Sun H; Nazare M; Berchner-Pfannschmidt U; von Kries JP; Eckstein A; Schülein R; Krause G
    Thyroid; 2019 Jan; 29(1):111-123. PubMed ID: 30351237
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Complete inhibition of rhTSH-, Graves' disease IgG-, and M22-induced cAMP production in differentiated orbital fibroblasts by a low-molecular-weight TSHR antagonist.
    van Zeijl CJ; van Koppen CJ; Surovtseva OV; de Gooyer ME; Plate R; Conti P; Karstens WJ; Timmers M; Saeed P; Wiersinga WM; Miltenburg AM; Fliers E; Boelen A
    J Clin Endocrinol Metab; 2012 May; 97(5):E781-5. PubMed ID: 22419705
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Evidence for protein and mRNA TSHr expression in fibroblasts from patients with thyroid-associated ophthalmopathy (TAO) after adipocytic differentiation.
    Agretti P; De Marco G; De Servi M; Marcocci C; Vitti P; Pinchera A; Tonacchera M
    Eur J Endocrinol; 2005 May; 152(5):777-84. PubMed ID: 15879364
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Evidence That Graves' Ophthalmopathy Immunoglobulins Do Not Directly Activate IGF-1 Receptors.
    Marcus-Samuels B; Krieger CC; Boutin A; Kahaly GJ; Neumann S; Gershengorn MC
    Thyroid; 2018 May; 28(5):650-655. PubMed ID: 29631510
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Immunopathogenesis of Graves' ophthalmopathy: the role of the TSH receptor.
    Iyer S; Bahn R
    Best Pract Res Clin Endocrinol Metab; 2012 Jun; 26(3):281-9. PubMed ID: 22632365
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 14.