765 related articles for article (PubMed ID: 23486940)
1. Enhancing mitochondrial calcium buffering capacity reduces aggregation of misfolded SOD1 and motor neuron cell death without extending survival in mouse models of inherited amyotrophic lateral sclerosis.
Parone PA; Da Cruz S; Han JS; McAlonis-Downes M; Vetto AP; Lee SK; Tseng E; Cleveland DW
J Neurosci; 2013 Mar; 33(11):4657-71. PubMed ID: 23486940
[TBL] [Abstract][Full Text] [Related]
2. The mitochondrial permeability transition pore in motor neurons: involvement in the pathobiology of ALS mice.
Martin LJ; Gertz B; Pan Y; Price AC; Molkentin JD; Chang Q
Exp Neurol; 2009 Aug; 218(2):333-46. PubMed ID: 19272377
[TBL] [Abstract][Full Text] [Related]
3. Human Cu/Zn superoxide dismutase (SOD1) overexpression in mice causes mitochondrial vacuolization, axonal degeneration, and premature motoneuron death and accelerates motoneuron disease in mice expressing a familial amyotrophic lateral sclerosis mutant SOD1.
Jaarsma D; Haasdijk ED; Grashorn JA; Hawkins R; van Duijn W; Verspaget HW; London J; Holstege JC
Neurobiol Dis; 2000 Dec; 7(6 Pt B):623-43. PubMed ID: 11114261
[TBL] [Abstract][Full Text] [Related]
4. RNS60 exerts therapeutic effects in the SOD1 ALS mouse model through protective glia and peripheral nerve rescue.
Vallarola A; Sironi F; Tortarolo M; Gatto N; De Gioia R; Pasetto L; De Paola M; Mariani A; Ghosh S; Watson R; Kalmes A; Bonetto V; Bendotti C
J Neuroinflammation; 2018 Mar; 15(1):65. PubMed ID: 29495962
[TBL] [Abstract][Full Text] [Related]
5. Delayed disease onset and extended survival in the SOD1G93A rat model of amyotrophic lateral sclerosis after suppression of mutant SOD1 in the motor cortex.
Thomsen GM; Gowing G; Latter J; Chen M; Vit JP; Staggenborg K; Avalos P; Alkaslasi M; Ferraiuolo L; Likhite S; Kaspar BK; Svendsen CN
J Neurosci; 2014 Nov; 34(47):15587-600. PubMed ID: 25411487
[TBL] [Abstract][Full Text] [Related]
6. The mitochondrial calcium regulator cyclophilin D is an essential component of oestrogen-mediated neuroprotection in amyotrophic lateral sclerosis.
Kim HJ; Magranè J; Starkov AA; Manfredi G
Brain; 2012 Sep; 135(Pt 9):2865-74. PubMed ID: 22961554
[TBL] [Abstract][Full Text] [Related]
7. In vivo pathogenic role of mutant SOD1 localized in the mitochondrial intermembrane space.
Igoudjil A; Magrané J; Fischer LR; Kim HJ; Hervias I; Dumont M; Cortez C; Glass JD; Starkov AA; Manfredi G
J Neurosci; 2011 Nov; 31(44):15826-37. PubMed ID: 22049426
[TBL] [Abstract][Full Text] [Related]
8. Calcium dysregulation, mitochondrial pathology and protein aggregation in a culture model of amyotrophic lateral sclerosis: mechanistic relationship and differential sensitivity to intervention.
Tradewell ML; Cooper LA; Minotti S; Durham HD
Neurobiol Dis; 2011 Jun; 42(3):265-75. PubMed ID: 21296666
[TBL] [Abstract][Full Text] [Related]
9. Complete dissociation of motor neuron death from motor dysfunction by Bax deletion in a mouse model of ALS.
Gould TW; Buss RR; Vinsant S; Prevette D; Sun W; Knudson CM; Milligan CE; Oppenheim RW
J Neurosci; 2006 Aug; 26(34):8774-86. PubMed ID: 16928866
[TBL] [Abstract][Full Text] [Related]
10. Targeting of monomer/misfolded SOD1 as a therapeutic strategy for amyotrophic lateral sclerosis.
Liu HN; Tjostheim S; Dasilva K; Taylor D; Zhao B; Rakhit R; Brown M; Chakrabartty A; McLaurin J; Robertson J
J Neurosci; 2012 Jun; 32(26):8791-9. PubMed ID: 22745481
[TBL] [Abstract][Full Text] [Related]
11. Mitochondria-targeted catalase reverts the neurotoxicity of hSOD1G⁹³A astrocytes without extending the survival of ALS-linked mutant hSOD1 mice.
Pehar M; Beeson G; Beeson CC; Johnson JA; Vargas MR
PLoS One; 2014; 9(7):e103438. PubMed ID: 25054289
[TBL] [Abstract][Full Text] [Related]
12. Transgenic mice with human mutant genes causing Parkinson's disease and amyotrophic lateral sclerosis provide common insight into mechanisms of motor neuron selective vulnerability to degeneration.
Martin LJ
Rev Neurosci; 2007; 18(2):115-36. PubMed ID: 17593875
[TBL] [Abstract][Full Text] [Related]
13. Early vacuolization and mitochondrial damage in motor neurons of FALS mice are not associated with apoptosis or with changes in cytochrome oxidase histochemical reactivity.
Bendotti C; Calvaresi N; Chiveri L; Prelle A; Moggio M; Braga M; Silani V; De Biasi S
J Neurol Sci; 2001 Oct; 191(1-2):25-33. PubMed ID: 11676989
[TBL] [Abstract][Full Text] [Related]
14. Amyotrophic lateral sclerosis-related mutant superoxide dismutase 1 aggregates inhibit 14-3-3-mediated cell survival by sequestration into the JUNQ compartment.
Park JH; Jang HR; Lee IY; Oh HK; Choi EJ; Rhim H; Kang S
Hum Mol Genet; 2017 Sep; 26(18):3615-3629. PubMed ID: 28666328
[TBL] [Abstract][Full Text] [Related]
15. Interaction between familial amyotrophic lateral sclerosis (ALS)-linked SOD1 mutants and the dynein complex.
Zhang F; Ström AL; Fukada K; Lee S; Hayward LJ; Zhu H
J Biol Chem; 2007 Jun; 282(22):16691-9. PubMed ID: 17403682
[TBL] [Abstract][Full Text] [Related]
16. Familial amyotrophic lateral sclerosis-linked SOD1 mutants perturb fast axonal transport to reduce axonal mitochondria content.
De Vos KJ; Chapman AL; Tennant ME; Manser C; Tudor EL; Lau KF; Brownlees J; Ackerley S; Shaw PJ; McLoughlin DM; Shaw CE; Leigh PN; Miller CCJ; Grierson AJ
Hum Mol Genet; 2007 Nov; 16(22):2720-2728. PubMed ID: 17725983
[TBL] [Abstract][Full Text] [Related]
17. Nuclear localization of human SOD1 and mutant SOD1-specific disruption of survival motor neuron protein complex in transgenic amyotrophic lateral sclerosis mice.
Gertz B; Wong M; Martin LJ
J Neuropathol Exp Neurol; 2012 Feb; 71(2):162-77. PubMed ID: 22249462
[TBL] [Abstract][Full Text] [Related]
18. Calcium-permeable AMPA receptors promote misfolding of mutant SOD1 protein and development of amyotrophic lateral sclerosis in a transgenic mouse model.
Tateno M; Sadakata H; Tanaka M; Itohara S; Shin RM; Miura M; Masuda M; Aosaki T; Urushitani M; Misawa H; Takahashi R
Hum Mol Genet; 2004 Oct; 13(19):2183-96. PubMed ID: 15294873
[TBL] [Abstract][Full Text] [Related]
19. Trehalose decreases mutant SOD1 expression and alleviates motor deficiency in early but not end-stage amyotrophic lateral sclerosis in a SOD1-G93A mouse model.
Li Y; Guo Y; Wang X; Yu X; Duan W; Hong K; Wang J; Han H; Li C
Neuroscience; 2015 Jul; 298():12-25. PubMed ID: 25841320
[TBL] [Abstract][Full Text] [Related]
20. Massive mitochondrial degeneration in motor neurons triggers the onset of amyotrophic lateral sclerosis in mice expressing a mutant SOD1.
Kong J; Xu Z
J Neurosci; 1998 May; 18(9):3241-50. PubMed ID: 9547233
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
