BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

187 related articles for article (PubMed ID: 23494117)

  • 1. Enhancement of 5-fluorouracil-induced cytotoxicity by leucovorin in 5-fluorouracil-resistant gastric cancer cells with upregulated expression of thymidylate synthase.
    Nakamura A; Nakajima G; Okuyama R; Kuramochi H; Kondoh Y; Kanemura T; Takechi T; Yamamoto M; Hayashi K
    Gastric Cancer; 2014 Jan; 17(1):188-95. PubMed ID: 23494117
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Synergistic antitumor effect of combined 5-fluorouracil (5-FU) with 5-chloro-2,4-dihydroxypyridine on 5-FU-resistant gastric cancer cells: possible role of a dihydropyrimidine dehydrogenase-independent mechanism.
    Sasaki E; Tominaga K; Kuwamura H; Watanabe T; Fujiwara Y; Oshitani N; Higuchi K; Arakawa T
    J Gastroenterol; 2007 Oct; 42(10):816-22. PubMed ID: 17940834
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Comparative cytotoxicity of folate-based inhibitors of thymidylate synthase and 5-fluorouracil +/- leucovorin in MGH-U1 cells.
    Erlichman C; Mitrovski B
    Cancer Chemother Pharmacol; 1994; 34(1):51-6. PubMed ID: 8174202
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Thymidylate synthase level as the main predictive parameter for sensitivity to 5-fluorouracil, but not for folate-based thymidylate synthase inhibitors, in 13 nonselected colon cancer cell lines.
    van Triest B; Pinedo HM; van Hensbergen Y; Smid K; Telleman F; Schoenmakers PS; van der Wilt CL; van Laar JA; Noordhuis P; Jansen G; Peters GJ
    Clin Cancer Res; 1999 Mar; 5(3):643-54. PubMed ID: 10100718
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Induction of thymidylate synthase as a 5-fluorouracil resistance mechanism.
    Peters GJ; Backus HH; Freemantle S; van Triest B; Codacci-Pisanelli G; van der Wilt CL; Smid K; Lunec J; Calvert AH; Marsh S; McLeod HL; Bloemena E; Meijer S; Jansen G; van Groeningen CJ; Pinedo HM
    Biochim Biophys Acta; 2002 Jul; 1587(2-3):194-205. PubMed ID: 12084461
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Selective protection by uridine of growth inhibition by 5-fluorouracil (5FU) mediated by 5FU incorporation into RNA, but not the thymidylate synthase mediated growth inhibition by 5FU-leucovorin.
    Codacci-Pisanelli G; Noordhuis P; van der Wilt CL; Peters GJ
    Nucleosides Nucleotides Nucleic Acids; 2008 Jun; 27(6):733-9. PubMed ID: 18600533
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The inhibition of thymidine phosphorylase can reverse acquired 5FU-resistance in gastric cancer cells.
    Mori R; Yoshida K; Futamura M; Suetsugu T; Shizu K; Tanahashi T; Tanaka Y; Matsuhashi N; Yamaguchi K
    Gastric Cancer; 2019 May; 22(3):497-505. PubMed ID: 30276573
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Trifluridine/tipiracil overcomes the resistance of human gastric 5-fluorouracil-refractory cells with high thymidylate synthase expression.
    Matsuoka K; Nakagawa F; Kobunai T; Takechi T
    Oncotarget; 2018 Mar; 9(17):13438-13450. PubMed ID: 29568368
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Elevation of thymidylate synthase following 5-fluorouracil treatment is prevented by the addition of leucovorin in murine colon tumors.
    Van der Wilt CL; Pinedo HM; Smid K; Peters GJ
    Cancer Res; 1992 Sep; 52(18):4922-8. PubMed ID: 1516048
    [TBL] [Abstract][Full Text] [Related]  

  • 10. 5-fluorouracil/leucovorin-induced inhibition of thymidylate synthase in normal tissues of mouse and man.
    van der Wilt CL; van Groeningen CJ; Pinedo HM; Smid K; Hoekman K; Meijer S; Peters GJ
    J Cancer Res Clin Oncol; 1997; 123(11-12):595-601. PubMed ID: 9620216
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Expression of thymidylate synthase, thymidine phosphorylase, dihydropyrimidine dehydrogenase, E2F-1, Bak, Bcl-X, and Bcl-2, and clinical outcomes for gastric cancer patients treated with bolus 5-fluorouracil.
    Tahara M; Ochiai A; Fujimoto J; Boku N; Yasui W; Ohtsu A; Tahara E; Yoshida S
    Oncol Rep; 2004 Jan; 11(1):9-15. PubMed ID: 14654896
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Decreased orotate phosphoribosyltransferase activity produces 5-fluorouracil resistance in a human gastric cancer cell line.
    Tsutani Y; Yoshida K; Sanada Y; Wada Y; Konishi K; Fukushima M; Okada M
    Oncol Rep; 2008 Dec; 20(6):1545-51. PubMed ID: 19020740
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Reduced activity of anabolizing enzymes in 5-fluorouracil-resistant human stomach cancer cells.
    Inaba M; Mitsuhashi J; Sawada H; Miike N; Naoe Y; Daimon A; Koizumi K; Tsujimoto H; Fukushima M
    Jpn J Cancer Res; 1996 Feb; 87(2):212-20. PubMed ID: 8609072
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Immunological quantitation of thymidylate synthase using the monoclonal antibody TS 106 in 5-fluorouracil-sensitive and -resistant human cancer cell lines.
    Johnston PG; Drake JC; Trepel J; Allegra CJ
    Cancer Res; 1992 Aug; 52(16):4306-12. PubMed ID: 1643628
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Correlation of thymidylate synthase, thymidine phosphorylase and dihydropyrimidine dehydrogenase with sensitivity of gastrointestinal cancer cells to 5-fluorouracil and 5-fluoro-2'-deoxyuridine.
    Ma T; Zhu ZG; Ji YB; Zhang Y; Yu YY; Liu BY; Yin HR; Lin YZ
    World J Gastroenterol; 2004 Jan; 10(2):172-6. PubMed ID: 14716816
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Thymidylate synthase and drug resistance.
    Peters GJ; van der Wilt CL; van Triest B; Codacci-Pisanelli G; Johnston PG; van Groeningen CJ; Pinedo HM
    Eur J Cancer; 1995; 31A(7-8):1299-305. PubMed ID: 7577040
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Thymidylate synthase protein expression in advanced colon cancer: correlation with the site of metastasis and the clinical response to leucovorin-modulated bolus 5-fluorouracil.
    Cascinu S; Aschele C; Barni S; Debernardis D; Baldo C; Tunesi G; Catalano V; Staccioli MP; Brenna A; Muretto P; Catalano G
    Clin Cancer Res; 1999 Aug; 5(8):1996-9. PubMed ID: 10473077
    [TBL] [Abstract][Full Text] [Related]  

  • 18. In vitro enhancement of fluoropyrimidine-induced cytotoxicity by leucovorin in colorectal and gastric carcinoma cell lines but not in non-small-cell lung carcinoma cell lines.
    Sugimoto Y; Ohe Y; Nishio K; Ohmori T; Fujiwara Y; Saijo N
    Cancer Chemother Pharmacol; 1992; 30(6):417-22. PubMed ID: 1327567
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Targeting Lactate Dehydrogenase A with Catechin Resensitizes SNU620/5FU Gastric Cancer Cells to 5-Fluorouracil.
    Han JH; Kim M; Kim HJ; Jang SB; Bae SJ; Lee IK; Ryu D; Ha KT
    Int J Mol Sci; 2021 May; 22(10):. PubMed ID: 34065602
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Thymidylate synthetase (TS) genotype and TS/dihydropyrimidine dehydrogenase mRNA level as an indicator in determining chemosensitivity to 5-fluorouracil in advanced gastric carcinoma.
    Toriumi F; Kubota T; Saikawa Y; Yoshida M; Otani Y; Watanabe M; Kumai K; Kitajima M
    Anticancer Res; 2004; 24(4):2455-63. PubMed ID: 15330198
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.