These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

170 related articles for article (PubMed ID: 23496136)

  • 1. Learning from nature: advances in geldanamycin- and radicicol-based inhibitors of Hsp90.
    Kitson RR; Moody CJ
    J Org Chem; 2013 Jun; 78(11):5117-41. PubMed ID: 23496136
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Design, synthesis, and structure--activity relationships for chimeric inhibitors of Hsp90.
    Shen G; Wang M; Welch TR; Blagg BS
    J Org Chem; 2006 Sep; 71(20):7618-31. PubMed ID: 16995666
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Geldanamycin, radicicol, and chimeric inhibitors of the Hsp90 N-terminal ATP binding site.
    Hadden MK; Lubbers DJ; Blagg BS
    Curr Top Med Chem; 2006; 6(11):1173-82. PubMed ID: 16842154
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Synthesis and evaluation of radamide analogues, a chimera of radicicol and geldanamycin.
    Hadden MK; Blagg BS
    J Org Chem; 2009 Jul; 74(13):4697-704. PubMed ID: 19492825
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Radicicol but not geldanamycin evokes oxidative stress response and efflux protein inhibition in ARPE-19 human retinal pigment epithelial cells.
    Ryhänen T; Mannermaa E; Oksala N; Viiri J; Paimela T; Salminen A; Atalay M; Kaarniranta K
    Eur J Pharmacol; 2008 Apr; 584(2-3):229-36. PubMed ID: 18313664
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Structure-based and in silico design of Hsp90 inhibitors.
    Sgobba M; Rastelli G
    ChemMedChem; 2009 Sep; 4(9):1399-409. PubMed ID: 19685544
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Radanamycin, a macrocyclic chimera of radicicol and geldanamycin.
    Wang M; Shen G; Blagg BS
    Bioorg Med Chem Lett; 2006 May; 16(9):2459-62. PubMed ID: 16464590
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Convergent synthesis and discovery of a natural product-inspired paralog-selective Hsp90 inhibitor.
    Jeso V; Cherry L; Macklin TK; Pan SC; LoGrasso PV; Micalizio GC
    Org Lett; 2011 Oct; 13(19):5108-11. PubMed ID: 21866939
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Spotlight on the microbes that produce heat shock protein 90-targeting antibiotics.
    Piper PW; Millson SH
    Open Biol; 2012 Dec; 2(12):120138. PubMed ID: 23271830
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Geldanamycin and its derivatives as Hsp90 inhibitors.
    Gorska M; Popowska U; Sielicka-Dudzin A; Kuban-Jankowska A; Sawczuk W; Knap N; Cicero G; Wozniak F
    Front Biosci (Landmark Ed); 2012 Jun; 17(6):2269-77. PubMed ID: 22652777
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Discovery and development of heat shock protein 90 inhibitors as anticancer agents: a review of patented potent geldanamycin derivatives.
    Kim T; Keum G; Pae AN
    Expert Opin Ther Pat; 2013 Aug; 23(8):919-43. PubMed ID: 23641970
    [TBL] [Abstract][Full Text] [Related]  

  • 12. An improved route to 19-substituted geldanamycins as novel Hsp90 inhibitors--potential therapeutics in cancer and neurodegeneration.
    Kitson RR; Moody CJ
    Chem Commun (Camb); 2013 Oct; 49(76):8441-3. PubMed ID: 23770604
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Optimizing natural products by biosynthetic engineering: discovery of nonquinone Hsp90 inhibitors.
    Zhang MQ; Gaisser S; Nur-E-Alam M; Sheehan LS; Vousden WA; Gaitatzis N; Peck G; Coates NJ; Moss SJ; Radzom M; Foster TA; Sheridan RM; Gregory MA; Roe SM; Prodromou C; Pearl L; Boyd SM; Wilkinson B; Martin CJ
    J Med Chem; 2008 Sep; 51(18):5494-7. PubMed ID: 18800759
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Natural Product Inspired N-Terminal Hsp90 Inhibitors: From Bench to Bedside?
    Khandelwal A; Crowley VM; Blagg BSJ
    Med Res Rev; 2016 Jan; 36(1):92-118. PubMed ID: 26010985
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Hydrating for resistance to radicicol.
    Duerfeldt AS; Blagg BS
    ACS Chem Biol; 2009 Apr; 4(4):245-7. PubMed ID: 19371133
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Antibiotic radicicol binds to the N-terminal domain of Hsp90 and shares important biologic activities with geldanamycin.
    Schulte TW; Akinaga S; Soga S; Sullivan W; Stensgard B; Toft D; Neckers LM
    Cell Stress Chaperones; 1998 Jun; 3(2):100-8. PubMed ID: 9672245
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Potent cytotoxic C-11 modified geldanamycin analogues.
    Tian ZQ; Wang Z; MacMillan KS; Zhou Y; Carreras CW; Mueller T; Myles DC; Liu Y
    J Med Chem; 2009 May; 52(10):3265-73. PubMed ID: 19405528
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Synthesis of macrolactam analogues of radicicol and their binding to heat shock protein Hsp90.
    Dutton BL; Kitson RR; Parry-Morris S; Roe SM; Prodromou C; Moody CJ
    Org Biomol Chem; 2014 Feb; 12(8):1328-40. PubMed ID: 24435512
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Computational predictions of corroles as a class of Hsp90 inhibitors.
    Teo RD; Dong SS; Gross Z; Gray HB; Goddard WA
    Mol Biosyst; 2015 Nov; 11(11):2907-14. PubMed ID: 26252737
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Synthesis of reblastatin, autolytimycin, and non-benzoquinone analogues: potent inhibitors of heat shock protein 90.
    Wrona IE; Gozman A; Taldone T; Chiosis G; Panek JS
    J Org Chem; 2010 May; 75(9):2820-35. PubMed ID: 20392070
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.