175 related articles for article (PubMed ID: 23499846)
1. The biological activities of protein/oleic acid complexes reside in the fatty acid.
Fontana A; Spolaore B; Polverino de Laureto P
Biochim Biophys Acta; 2013 Jun; 1834(6):1125-43. PubMed ID: 23499846
[TBL] [Abstract][Full Text] [Related]
2. Structure and function of human α-lactalbumin made lethal to tumor cells (HAMLET)-type complexes.
Mossberg AK; Hun Mok K; Morozova-Roche LA; Svanborg C
FEBS J; 2010 Nov; 277(22):4614-25. PubMed ID: 20977665
[TBL] [Abstract][Full Text] [Related]
3. Who is Mr. HAMLET? Interaction of human alpha-lactalbumin with monomeric oleic acid.
Knyazeva EL; Grishchenko VM; Fadeev RS; Akatov VS; Permyakov SE; Permyakov EA
Biochemistry; 2008 Dec; 47(49):13127-37. PubMed ID: 19006329
[TBL] [Abstract][Full Text] [Related]
4. α-Lactalbumin forms with oleic acid a high molecular weight complex displaying cytotoxic activity.
Spolaore B; Pinato O; Canton M; Zambonin M; Polverino de Laureto P; Fontana A
Biochemistry; 2010 Oct; 49(39):8658-67. PubMed ID: 20804154
[TBL] [Abstract][Full Text] [Related]
5. A novel method for preparation of HAMLET-like protein complexes.
Permyakov SE; Knyazeva EL; Leonteva MV; Fadeev RS; Chekanov AV; Zhadan AP; Håkansson AP; Akatov VS; Permyakov EA
Biochimie; 2011 Sep; 93(9):1495-501. PubMed ID: 21596091
[TBL] [Abstract][Full Text] [Related]
6. Applications of site-specific labeling to study HAMLET, a tumoricidal complex of α-lactalbumin and oleic acid.
Mercer N; Ramakrishnan B; Boeggeman E; Qasba PK
PLoS One; 2011; 6(10):e26093. PubMed ID: 22016817
[TBL] [Abstract][Full Text] [Related]
7. alpha-Lactalbumin, engineered to be nonnative and inactive, kills tumor cells when in complex with oleic acid: a new biological function resulting from partial unfolding.
Pettersson-Kastberg J; Mossberg AK; Trulsson M; Yong YJ; Min S; Lim Y; O'Brien JE; Svanborg C; Mok KH
J Mol Biol; 2009 Dec; 394(5):994-1010. PubMed ID: 19766653
[TBL] [Abstract][Full Text] [Related]
8. Molecular mechanisms of the cytotoxicity of human α-lactalbumin made lethal to tumor cells (HAMLET) and other protein-oleic acid complexes.
Nakamura T; Aizawa T; Kariya R; Okada S; Demura M; Kawano K; Makabe K; Kuwajima K
J Biol Chem; 2013 May; 288(20):14408-14416. PubMed ID: 23580643
[TBL] [Abstract][Full Text] [Related]
9. Protein-fatty acid complexes: biochemistry, biophysics and function.
Brinkmann CR; Thiel S; Otzen DE
FEBS J; 2013 Apr; 280(8):1733-49. PubMed ID: 23441831
[TBL] [Abstract][Full Text] [Related]
10. Bovine lactoferrin binds oleic acid to form an anti-tumor complex similar to HAMLET.
Fang B; Zhang M; Tian M; Jiang L; Guo HY; Ren FZ
Biochim Biophys Acta; 2014 Apr; 1841(4):535-43. PubMed ID: 24368211
[TBL] [Abstract][Full Text] [Related]
11. The oleic acid complexes of proteolytic fragments of alpha-lactalbumin display apoptotic activity.
Tolin S; De Franceschi G; Spolaore B; Frare E; Canton M; Polverino de Laureto P; Fontana A
FEBS J; 2010 Jan; 277(1):163-73. PubMed ID: 19968717
[TBL] [Abstract][Full Text] [Related]
12. Cytotoxicity of bovine α-lactalbumin: oleic acid complexes correlates with the disruption of lipid membranes.
Wen H; Glomm WR; Halskau O
Biochim Biophys Acta; 2013 Nov; 1828(11):2691-9. PubMed ID: 23916586
[TBL] [Abstract][Full Text] [Related]
13. Electrostatic interactions play an essential role in the binding of oleic acid with α-lactalbumin in the HAMLET-like complex: a study using charge-specific chemical modifications.
Xie Y; Min S; Harte NP; Kirk H; O'Brien JE; Voorheis HP; Svanborg C; Hun Mok K
Proteins; 2013 Jan; 81(1):1-17. PubMed ID: 22777854
[TBL] [Abstract][Full Text] [Related]
14. Molten globule of bovine alpha-lactalbumin at neutral pH induced by heat, trifluoroethanol, and oleic acid: a comparative analysis by circular dichroism spectroscopy and limited proteolysis.
Polverino de Laureto P; Frare E; Gottardo R; Fontana A
Proteins; 2002 Nov; 49(3):385-97. PubMed ID: 12360528
[TBL] [Abstract][Full Text] [Related]
15. Oleic acid is a key cytotoxic component of HAMLET-like complexes.
Permyakov SE; Knyazeva EL; Khasanova LM; Fadeev RS; Zhadan AP; Roche-Hakansson H; Håkansson AP; Akatov VS; Permyakov EA
Biol Chem; 2012 Jan; 393(1-2):85-92. PubMed ID: 22628302
[TBL] [Abstract][Full Text] [Related]
16. α-Lactalbumin:Oleic Acid Complex Spontaneously Delivers Oleic Acid to Artificial and Erythrocyte Membranes.
Wen H; Strømland Ø; Halskau Ø
J Mol Biol; 2015 Sep; 427(19):3177-87. PubMed ID: 26297199
[TBL] [Abstract][Full Text] [Related]
17. Alternatively folded proteins with unexpected beneficial functions.
Min S; Meehan J; Sullivan LM; Harte NP; Xie Y; Davey GP; Svanborg C; Brodkorb A; Mok KH
Biochem Soc Trans; 2012 Aug; 40(4):746-51. PubMed ID: 22817727
[TBL] [Abstract][Full Text] [Related]
18. Structure and stability analysis of cytotoxic complex of camel α-lactalbumin and unsaturated fatty acids produced at high temperature.
Atri MS; Saboury AA; Moosavi-Movahedi AA; Goliaei B; Sefidbakht Y; Alijanvand HH; Sharifzadeh A; Niasari-Naslaji A
J Biomol Struct Dyn; 2011 Jun; 28(6):919-28. PubMed ID: 21469752
[TBL] [Abstract][Full Text] [Related]
19. Compact oleic acid in HAMLET.
Fast J; Mossberg AK; Nilsson H; Svanborg C; Akke M; Linse S
FEBS Lett; 2005 Nov; 579(27):6095-100. PubMed ID: 16229842
[TBL] [Abstract][Full Text] [Related]
20. Apoptosis and tumor cell death in response to HAMLET (human alpha-lactalbumin made lethal to tumor cells).
Hallgren O; Aits S; Brest P; Gustafsson L; Mossberg AK; Wullt B; Svanborg C
Adv Exp Med Biol; 2008; 606():217-40. PubMed ID: 18183931
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
