BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

215 related articles for article (PubMed ID: 23505424)

  • 1. Cellular effects of curcumin on Plasmodium falciparum include disruption of microtubules.
    Chakrabarti R; Rawat PS; Cooke BM; Coppel RL; Patankar S
    PLoS One; 2013; 8(3):e57302. PubMed ID: 23505424
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The novel microtubule-destabilizing drug BAL27862 binds to the colchicine site of tubulin with distinct effects on microtubule organization.
    Prota AE; Danel F; Bachmann F; Bargsten K; Buey RM; Pohlmann J; Reinelt S; Lane H; Steinmetz MO
    J Mol Biol; 2014 Apr; 426(8):1848-60. PubMed ID: 24530796
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Combination Assays and Molecular Docking can Identify Binding sites of Anti-Microtubule Drugs on Plasmodium falciparum Tubulin.
    Chakrabarti R; Patankar S
    Infect Disord Drug Targets; 2016; 16(3):204-216. PubMed ID: 27401470
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Griseofulvin stabilizes microtubule dynamics, activates p53 and inhibits the proliferation of MCF-7 cells synergistically with vinblastine.
    Rathinasamy K; Jindal B; Asthana J; Singh P; Balaji PV; Panda D
    BMC Cancer; 2010 May; 10():213. PubMed ID: 20482847
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Dietary antioxidant curcumin inhibits microtubule assembly through tubulin binding.
    Gupta KK; Bharne SS; Rathinasamy K; Naik NR; Panda D
    FEBS J; 2006 Dec; 273(23):5320-32. PubMed ID: 17069615
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Novel quinolone chalcones targeting colchicine-binding pocket kill multidrug-resistant cancer cells by inhibiting tubulin activity and MRP1 function.
    Lindamulage IK; Vu HY; Karthikeyan C; Knockleby J; Lee YF; Trivedi P; Lee H
    Sci Rep; 2017 Aug; 7(1):10298. PubMed ID: 28860494
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Indirubin, a bis-indole alkaloid binds to tubulin and exhibits antimitotic activity against HeLa cells in synergism with vinblastine.
    Mohan L; Raghav D; Ashraf SM; Sebastian J; Rathinasamy K
    Biomed Pharmacother; 2018 Sep; 105():506-517. PubMed ID: 29883946
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Discovery of potent microtubule-destabilizing agents targeting for colchicine site by virtual screening, biological evaluation, and molecular dynamics simulation.
    Zhang H; Luo QQ; Hu ML; Wang N; Qi HZ; Zhang HR; Ding L
    Eur J Pharm Sci; 2023 Jan; 180():106340. PubMed ID: 36435355
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Recent advances in research of colchicine binding site inhibitors and their interaction modes with tubulin.
    Sun K; Sun Z; Zhao F; Shan G; Meng Q
    Future Med Chem; 2021 May; 13(9):839-858. PubMed ID: 33821673
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Purification of functional Plasmodium falciparum tubulin allows for the identification of parasite-specific microtubule inhibitors.
    Hirst WG; Fachet D; Kuropka B; Weise C; Saliba KJ; Reber S
    Curr Biol; 2022 Feb; 32(4):919-926.e6. PubMed ID: 35051355
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Perturbation of microtubule polymerization by quercetin through tubulin binding: a novel mechanism of its antiproliferative activity.
    Gupta K; Panda D
    Biochemistry; 2002 Oct; 41(43):13029-38. PubMed ID: 12390030
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Structural insights into the design of indole derivatives as tubulin polymerization inhibitors.
    Li Y; Yang J; Niu L; Hu D; Li H; Chen L; Yu Y; Chen Q
    FEBS Lett; 2020 Jan; 594(1):199-204. PubMed ID: 31369682
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Distinct pose of discodermolide in taxol binding pocket drives a complementary mode of microtubule stabilization.
    Khrapunovich-Baine M; Menon V; Verdier-Pinard P; Smith AB; Angeletti RH; Fiser A; Horwitz SB; Xiao H
    Biochemistry; 2009 Dec; 48(49):11664-77. PubMed ID: 19863156
    [TBL] [Abstract][Full Text] [Related]  

  • 14. An antitubulin agent BCFMT inhibits proliferation of cancer cells and induces cell death by inhibiting microtubule dynamics.
    Rai A; Surolia A; Panda D
    PLoS One; 2012; 7(8):e44311. PubMed ID: 22952952
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Dietary flavonoid fisetin binds to β-tubulin and disrupts microtubule dynamics in prostate cancer cells.
    Mukhtar E; Adhami VM; Sechi M; Mukhtar H
    Cancer Lett; 2015 Oct; 367(2):173-83. PubMed ID: 26235140
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Microtubules in Plasmodium falciparum merozoites and their importance for invasion of erythrocytes.
    Fowler RE; Fookes RE; Lavin F; Bannister LH; Mitchell GH
    Parasitology; 1998 Nov; 117 ( Pt 5)():425-33. PubMed ID: 9836307
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Cyclostreptin binds covalently to microtubule pores and lumenal taxoid binding sites.
    Buey RM; Calvo E; Barasoain I; Pineda O; Edler MC; Matesanz R; Cerezo G; Vanderwal CD; Day BW; Sorensen EJ; López JA; Andreu JM; Hamel E; Díaz JF
    Nat Chem Biol; 2007 Feb; 3(2):117-25. PubMed ID: 17206139
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Tivantinib (ARQ 197) exhibits antitumor activity by directly interacting with tubulin and overcomes ABC transporter-mediated drug resistance.
    Aoyama A; Katayama R; Oh-Hara T; Sato S; Okuno Y; Fujita N
    Mol Cancer Ther; 2014 Dec; 13(12):2978-90. PubMed ID: 25313010
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Targeting Tubulin-colchicine Site for Cancer Therapy: Inhibitors, Antibody- Drug Conjugates and Degradation Agents.
    Duan Y; Liu W; Tian L; Mao Y; Song C
    Curr Top Med Chem; 2019; 19(15):1289-1304. PubMed ID: 31210108
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The compound millepachine and its derivatives inhibit tubulin polymerization by irreversibly binding to the colchicine-binding site in β-tubulin.
    Yang J; Yan W; Yu Y; Wang Y; Yang T; Xue L; Yuan X; Long C; Liu Z; Chen X; Hu M; Zheng L; Qiu Q; Pei H; Li D; Wang F; Bai P; Wen J; Ye H; Chen L
    J Biol Chem; 2018 Jun; 293(24):9461-9472. PubMed ID: 29691282
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.