These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

233 related articles for article (PubMed ID: 23514105)

  • 1. Lack of association of rare functional variants in TSC1/TSC2 genes with autism spectrum disorder.
    Bahl S; Chiang C; Beauchamp RL; Neale BM; Daly MJ; Gusella JF; Talkowski ME; Ramesh V
    Mol Autism; 2013 Mar; 4(1):5. PubMed ID: 23514105
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The E3 ubiquitin ligase protein associated with Myc (Pam) regulates mammalian/mechanistic target of rapamycin complex 1 (mTORC1) signaling in vivo through N- and C-terminal domains.
    Han S; Kim S; Bahl S; Li L; Burande CF; Smith N; James M; Beauchamp RL; Bhide P; DiAntonio A; Ramesh V
    J Biol Chem; 2012 Aug; 287(36):30063-72. PubMed ID: 22798074
    [TBL] [Abstract][Full Text] [Related]  

  • 3. TSC patient-derived isogenic neural progenitor cells reveal altered early neurodevelopmental phenotypes and rapamycin-induced MNK-eIF4E signaling.
    Martin P; Wagh V; Reis SA; Erdin S; Beauchamp RL; Shaikh G; Talkowski M; Thiele E; Sheridan SD; Haggarty SJ; Ramesh V
    Mol Autism; 2020; 11(1):2. PubMed ID: 31921404
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Pam and its ortholog highwire interact with and may negatively regulate the TSC1.TSC2 complex.
    Murthy V; Han S; Beauchamp RL; Smith N; Haddad LA; Ito N; Ramesh V
    J Biol Chem; 2004 Jan; 279(2):1351-8. PubMed ID: 14559897
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Pam (Protein associated with Myc) functions as an E3 ubiquitin ligase and regulates TSC/mTOR signaling.
    Han S; Witt RM; Santos TM; Polizzano C; Sabatini BL; Ramesh V
    Cell Signal; 2008 Jun; 20(6):1084-91. PubMed ID: 18308511
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Analysis of 65 tuberous sclerosis complex (TSC) patients by TSC2 DGGE, TSC1/TSC2 MLPA, and TSC1 long-range PCR sequencing, and report of 28 novel mutations.
    Rendtorff ND; Bjerregaard B; Frödin M; Kjaergaard S; Hove H; Skovby F; Brøndum-Nielsen K; Schwartz M;
    Hum Mutat; 2005 Oct; 26(4):374-83. PubMed ID: 16114042
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Structure of the Tuberous Sclerosis Complex 2 (TSC2) N Terminus Provides Insight into Complex Assembly and Tuberous Sclerosis Pathogenesis.
    Zech R; Kiontke S; Mueller U; Oeckinghaus A; Kümmel D
    J Biol Chem; 2016 Sep; 291(38):20008-20. PubMed ID: 27493206
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Pharmacological intervention to restore connectivity deficits of neuronal networks derived from ASD patient iPSC with a TSC2 mutation.
    Alsaqati M; Heine VM; Harwood AJ
    Mol Autism; 2020 Oct; 11(1):80. PubMed ID: 33076974
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The Neurodevelopmental Pathogenesis of Tuberous Sclerosis Complex (TSC).
    Feliciano DM
    Front Neuroanat; 2020; 14():39. PubMed ID: 32765227
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Mutation screening of the entire coding regions of the TSC1 and the TSC2 gene with the protein truncation test (PTT) identifies frequent splicing defects.
    Mayer K; Ballhausen W; Rott HD
    Hum Mutat; 1999; 14(5):401-11. PubMed ID: 10533066
    [TBL] [Abstract][Full Text] [Related]  

  • 11. A circuitry and biochemical basis for tuberous sclerosis symptoms: from epilepsy to neurocognitive deficits.
    Feliciano DM; Lin TV; Hartman NW; Bartley CM; Kubera C; Hsieh L; Lafourcade C; O'Keefe RA; Bordey A
    Int J Dev Neurosci; 2013 Nov; 31(7):667-78. PubMed ID: 23485365
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Architecture of the Tuberous Sclerosis Protein Complex.
    Ramlaul K; Fu W; Li H; de Martin Garrido N; He L; Trivedi M; Cui W; Aylett CHS; Wu G
    J Mol Biol; 2021 Jan; 433(2):166743. PubMed ID: 33307091
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Translatome analysis of Tuberous Sclerosis Complex-1 patient-derived neural progenitor cells reveal rapamycin-dependent and independent alterations.
    Aksoylu IS; Martin P; Robert F; Szkop KJ; Redmond NE; Chen S; Beauchamp RL; Nobeli I; Pelletier J; Larsson O; Ramesh V
    Res Sq; 2023 Mar; ():. PubMed ID: 37034588
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Biallelic TSC gene inactivation in tuberous sclerosis complex.
    Crino PB; Aronica E; Baltuch G; Nathanson KL
    Neurology; 2010 May; 74(21):1716-23. PubMed ID: 20498439
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Pathogenic
    Lee WS; Macdonald-Laurs E; Stephenson S; D'Arcy C; Maixner W; Harvey AS; Lockhart PJ; Leventer RJ
    Neurology; 2023 Jul; 101(2):78-82. PubMed ID: 37015817
    [TBL] [Abstract][Full Text] [Related]  

  • 16.
    Riley VA; Holmberg JC; Sokolov AM; Feliciano DM
    Front Mol Neurosci; 2022; 15():970357. PubMed ID: 36277492
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Functional assessment of variants in the TSC1 and TSC2 genes identified in individuals with Tuberous Sclerosis Complex.
    Hoogeveen-Westerveld M; Wentink M; van den Heuvel D; Mozaffari M; Ekong R; Povey S; den Dunnen JT; Metcalfe K; Vallee S; Krueger S; Bergoffen J; Shashi V; Elmslie F; Kwiatkowski D; Sampson J; Vidales C; Dzarir J; Garcia-Planells J; Dies K; Maat-Kievit A; van den Ouweland A; Halley D; Nellist M
    Hum Mutat; 2011 Apr; 32(4):424-35. PubMed ID: 21309039
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Analysis of both TSC1 and TSC2 for germline mutations in 126 unrelated patients with tuberous sclerosis.
    Niida Y; Lawrence-Smith N; Banwell A; Hammer E; Lewis J; Beauchamp RL; Sims K; Ramesh V; Ozelius L
    Hum Mutat; 1999; 14(5):412-22. PubMed ID: 10533067
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The mTOR/S6K signalling pathway: the role of the TSC1/2 tumour suppressor complex and the proto-oncogene Rheb.
    Nobukini T; Thomas G
    Novartis Found Symp; 2004; 262():148-54; discussion 154-9, 265-8. PubMed ID: 15562827
    [TBL] [Abstract][Full Text] [Related]  

  • 20. TBC1D7 is a third subunit of the TSC1-TSC2 complex upstream of mTORC1.
    Dibble CC; Elis W; Menon S; Qin W; Klekota J; Asara JM; Finan PM; Kwiatkowski DJ; Murphy LO; Manning BD
    Mol Cell; 2012 Aug; 47(4):535-46. PubMed ID: 22795129
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.