BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

207 related articles for article (PubMed ID: 23515184)

  • 1. Comparable dimerization found in wildtype and familial Alzheimer's disease amyloid precursor protein mutants.
    So PP; Khodr CE; Chen CD; Abraham CR
    Am J Neurodegener Dis; 2013; 2(1):15-28. PubMed ID: 23515184
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Analysis by a highly sensitive split luciferase assay of the regions involved in APP dimerization and its impact on processing.
    Decock M; El Haylani L; Stanga S; Dewachter I; Octave JN; Smith SO; Constantinescu SN; Kienlen-Campard P
    FEBS Open Bio; 2015; 5():763-73. PubMed ID: 26500837
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Alanine substitutions in the GXXXG motif alter C99 cleavage by γ-secretase but not its dimerization.
    Higashide H; Ishihara S; Nobuhara M; Ihara Y; Funamoto S
    J Neurochem; 2017 Mar; 140(6):955-962. PubMed ID: 28032911
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Localization and Trafficking of Amyloid-β Protein Precursor and Secretases: Impact on Alzheimer's Disease.
    Agostinho P; Pliássova A; Oliveira CR; Cunha RA
    J Alzheimers Dis; 2015; 45(2):329-47. PubMed ID: 25589722
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Dimerization of the transmembrane domain of amyloid precursor proteins and familial Alzheimer's disease mutants.
    Gorman PM; Kim S; Guo M; Melnyk RA; McLaurin J; Fraser PE; Bowie JU; Chakrabartty A
    BMC Neurosci; 2008 Jan; 9():17. PubMed ID: 18234110
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Glycines from the APP GXXXG/GXXXA Transmembrane Motifs Promote Formation of Pathogenic Aβ Oligomers in Cells.
    Decock M; Stanga S; Octave JN; Dewachter I; Smith SO; Constantinescu SN; Kienlen-Campard P
    Front Aging Neurosci; 2016; 8():107. PubMed ID: 27242518
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Cholesterol-lowering drugs reduce APP processing to Aβ by inducing APP dimerization.
    Langness VF; van der Kant R; Das U; Wang L; Chaves RDS; Goldstein LSB
    Mol Biol Cell; 2021 Feb; 32(3):247-259. PubMed ID: 33296223
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Molecular determinants and thermodynamics of the amyloid precursor protein transmembrane domain implicated in Alzheimer's disease.
    Wang H; Barreyro L; Provasi D; Djemil I; Torres-Arancivia C; Filizola M; Ubarretxena-Belandia I
    J Mol Biol; 2011 May; 408(5):879-95. PubMed ID: 21440556
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Detection of amyloid-β protein precursor homo-interactions using beta-galactosidase enzyme fragment complementation.
    So PP; Chen CD; Abraham CR
    J Alzheimers Dis; 2011; 26(4):647-55. PubMed ID: 21694460
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Segregation of a missense mutation in the amyloid beta-protein precursor gene with familial Alzheimer's disease.
    Goate A
    J Alzheimers Dis; 2006; 9(3 Suppl):341-7. PubMed ID: 16914872
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Evidence For and Against a Pathogenic Role of Reduced γ-Secretase Activity in Familial Alzheimer's Disease.
    Jayne T; Newman M; Verdile G; Sutherland G; Münch G; Musgrave I; Moussavi Nik SH; Lardelli M
    J Alzheimers Dis; 2016 Apr; 52(3):781-99. PubMed ID: 27060961
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Mitochondria-targeted catalase reduces abnormal APP processing, amyloid β production and BACE1 in a mouse model of Alzheimer's disease: implications for neuroprotection and lifespan extension.
    Mao P; Manczak M; Calkins MJ; Truong Q; Reddy TP; Reddy AP; Shirendeb U; Lo HH; Rabinovitch PS; Reddy PH
    Hum Mol Genet; 2012 Jul; 21(13):2973-90. PubMed ID: 22492996
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Amyloid-β production via cleavage of amyloid-β protein precursor is modulated by cell density.
    Zhang C; Browne A; Divito JR; Stevenson JA; Romano D; Dong Y; Xie Z; Tanzi RE
    J Alzheimers Dis; 2010; 22(2):683-984. PubMed ID: 20847415
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Increased Foxo3a Nuclear Translocation and Activity is an Early Neuronal Response to βγ-Secretase-Mediated Processing of the Amyloid-β Protein Precursor: Utility of an AβPP-GAL4 Reporter Assay.
    Law BM; Guest AL; Pullen MWJ; Perkinton MS; Williams RJ
    J Alzheimers Dis; 2018; 61(2):673-688. PubMed ID: 29254083
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Familial Alzheimer's disease mutations in amyloid protein precursor alter proteolysis by γ-secretase to increase amyloid β-peptides of ≥45 residues.
    Devkota S; Williams TD; Wolfe MS
    J Biol Chem; 2021; 296():100281. PubMed ID: 33450230
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Lowering of amyloid beta peptide production with a small molecule inhibitor of amyloid-β precursor protein dimerization.
    So PP; Zeldich E; Seyb KI; Huang MM; Concannon JB; King GD; Chen CD; Cuny GD; Glicksman MA; Abraham CR
    Am J Neurodegener Dis; 2012; 1(1):75-87. PubMed ID: 22822474
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Small Molecule Amyloid-β Protein Precursor Processing Modulators Lower Amyloid-β Peptide Levels via cKit Signaling.
    Chen CD; Zeldich E; Khodr C; Camara K; Tung TY; Lauder EC; Mullen P; Polanco TJ; Liu YY; Zeldich D; Xia W; Van Nostrand WE; Brown LE; Porco JA; Abraham CR
    J Alzheimers Dis; 2019; 67(3):1089-1106. PubMed ID: 30776010
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Resveratrol Intervenes Cholesterol- and Isoprenoid-Mediated Amyloidogenic Processing of AβPP in Familial Alzheimer's Disease.
    Sathya M; Moorthi P; Premkumar P; Kandasamy M; Jayachandran KS; Anusuyadevi M
    J Alzheimers Dis; 2017; 60(s1):S3-S23. PubMed ID: 28059793
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Amyloid-beta protein precursor (AbetaPP) intracellular domain-associated protein-1 proteins bind to AbetaPP and modulate its processing in an isoform-specific manner.
    Ghersi E; Noviello C; D'Adamio L
    J Biol Chem; 2004 Nov; 279(47):49105-12. PubMed ID: 15347684
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Upregulation of Alzheimer's Disease Amyloid-β Protein Precursor in Astrocytes Both in vitro and in vivo.
    Liang Y; Raven F; Ward JF; Zhen S; Zhang S; Sun H; Miller SJ; Choi SH; Tanzi RE; Zhang C
    J Alzheimers Dis; 2020; 76(3):1071-1082. PubMed ID: 32597805
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.