BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

170 related articles for article (PubMed ID: 23515289)

  • 1. Investigating new therapeutic strategies targeting hyperinsulinemia's mitogenic effects in a female mouse breast cancer model.
    Rostoker R; Bitton-Worms K; Caspi A; Shen-Orr Z; LeRoith D
    Endocrinology; 2013 May; 154(5):1701-10. PubMed ID: 23515289
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Insulin receptor phosphorylation by endogenous insulin or the insulin analog AspB10 promotes mammary tumor growth independent of the IGF-I receptor.
    Gallagher EJ; Alikhani N; Tobin-Hess A; Blank J; Buffin NJ; Zelenko Z; Tennagels N; Werner U; LeRoith D
    Diabetes; 2013 Oct; 62(10):3553-60. PubMed ID: 23835331
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Highly specific role of the insulin receptor in breast cancer progression.
    Rostoker R; Abelson S; Bitton-Worms K; Genkin I; Ben-Shmuel S; Dakwar M; Orr ZS; Caspi A; Tzukerman M; LeRoith D
    Endocr Relat Cancer; 2015 Apr; 22(2):145-57. PubMed ID: 25694511
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Hyperinsulinemia enhances c-Myc-mediated mammary tumor development and advances metastatic progression to the lung in a mouse model of type 2 diabetes.
    Ferguson RD; Novosyadlyy R; Fierz Y; Alikhani N; Sun H; Yakar S; Leroith D
    Breast Cancer Res; 2012 Jan; 14(1):R8. PubMed ID: 22226054
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Targeting the insulin-like growth factor-1 receptor by picropodophyllin for lung cancer chemoprevention.
    Zhang Q; Pan J; Lubet RA; Wang Y; You M
    Mol Carcinog; 2015 Jun; 54 Suppl 1():E129-37. PubMed ID: 25163779
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Inhibition of in vivo breast cancer growth by antisense oligodeoxynucleotides to type I insulin-like growth factor receptor mRNA involves inactivation of ErbBs, PI-3K/Akt and p42/p44 MAPK signaling pathways but not modulation of progesterone receptor activity.
    Salatino M; Schillaci R; Proietti CJ; Carnevale R; Frahm I; Molinolo AA; Iribarren A; Charreau EH; Elizalde PV
    Oncogene; 2004 Jul; 23(30):5161-74. PubMed ID: 15122317
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Treatment of human breast cancer cells with antisense RNA to the type I insulin-like growth factor receptor inhibits cell growth, suppresses tumorigenesis, alters the metastatic potential, and prolongs survival in vivo.
    Chernicky CL; Yi L; Tan H; Gan SU; Ilan J
    Cancer Gene Ther; 2000 Mar; 7(3):384-95. PubMed ID: 10766344
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Insulin-mediated acceleration of breast cancer development and progression in a nonobese model of type 2 diabetes.
    Novosyadlyy R; Lann DE; Vijayakumar A; Rowzee A; Lazzarino DA; Fierz Y; Carboni JM; Gottardis MM; Pennisi PA; Molinolo AA; Kurshan N; Mejia W; Santopietro S; Yakar S; Wood TL; LeRoith D
    Cancer Res; 2010 Jan; 70(2):741-51. PubMed ID: 20068149
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Differential insulin-like growth factor I receptor signaling and function in estrogen receptor (ER)-positive MCF-7 and ER-negative MDA-MB-231 breast cancer cells.
    Bartucci M; Morelli C; Mauro L; Andò S; Surmacz E
    Cancer Res; 2001 Sep; 61(18):6747-54. PubMed ID: 11559546
    [TBL] [Abstract][Full Text] [Related]  

  • 10. A fully human monoclonal antibody to the insulin-like growth factor I receptor blocks ligand-dependent signaling and inhibits human tumor growth in vivo.
    Burtrum D; Zhu Z; Lu D; Anderson DM; Prewett M; Pereira DS; Bassi R; Abdullah R; Hooper AT; Koo H; Jimenez X; Johnson D; Apblett R; Kussie P; Bohlen P; Witte L; Hicklin DJ; Ludwig DL
    Cancer Res; 2003 Dec; 63(24):8912-21. PubMed ID: 14695208
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Reversibility and recurrence of IGF-IR-induced mammary tumors.
    Jones RA; Campbell CI; Wood GA; Petrik JJ; Moorehead RA
    Oncogene; 2009 May; 28(21):2152-62. PubMed ID: 19377512
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Growth-inhibitory effects of human anti-insulin-like growth factor-I receptor antibody (A12) in an orthotopic nude mouse model of anaplastic thyroid carcinoma.
    Wang Z; Chakravarty G; Kim S; Yazici YD; Younes MN; Jasser SA; Santillan AA; Bucana CD; El-Naggar AK; Myers JN
    Clin Cancer Res; 2006 Aug; 12(15):4755-65. PubMed ID: 16899627
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Picropodophyllin inhibits type I endometrial cancer cell proliferation via disruption of the PI3K/Akt pathway.
    Dong L; Du M; Lv Q
    Acta Biochim Biophys Sin (Shanghai); 2019 Jul; 51(7):753-760. PubMed ID: 31168597
    [TBL] [Abstract][Full Text] [Related]  

  • 14. IGF-1 receptor inhibition by picropodophyllin in medulloblastoma.
    Ohshima-Hosoyama S; Hosoyama T; Nelon LD; Keller C
    Biochem Biophys Res Commun; 2010 Sep; 399(4):727-32. PubMed ID: 20692232
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Insulin-like growth factor receptor as a therapeutic target in head and neck cancer.
    Barnes CJ; Ohshiro K; Rayala SK; El-Naggar AK; Kumar R
    Clin Cancer Res; 2007 Jul; 13(14):4291-9. PubMed ID: 17634559
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The insulin-like growth factor-I receptor inhibitor picropodophyllin causes tumor regression and attenuates mechanisms involved in invasion of uveal melanoma cells.
    Girnita A; All-Ericsson C; Economou MA; Aström K; Axelson M; Seregard S; Larsson O; Girnita L
    Clin Cancer Res; 2006 Feb; 12(4):1383-91. PubMed ID: 16489097
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Plasma and tissue insulin-like growth factor-I receptor (IGF-IR) as a prognostic marker for prostate cancer and anti-IGF-IR agents as novel therapeutic strategy for refractory cases: a review.
    Ozkan EE
    Mol Cell Endocrinol; 2011 Sep; 344(1-2):1-24. PubMed ID: 21782884
    [TBL] [Abstract][Full Text] [Related]  

  • 18. EMT reversal in human cancer cells after IR knockdown in hyperinsulinemic mice.
    Zelenko Z; Gallagher EJ; Antoniou IM; Sachdev D; Nayak A; Yee D; LeRoith D
    Endocr Relat Cancer; 2016 Sep; 23(9):747-58. PubMed ID: 27435064
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Role of estrogen receptor alpha in modulating IGF-I receptor signaling and function in breast cancer.
    Surmacz E; Bartucci M
    J Exp Clin Cancer Res; 2004 Sep; 23(3):385-94. PubMed ID: 15595626
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Control of apoptosis in human multiple myeloma by insulin-like growth factor I (IGF-I).
    Jernberg-Wiklund H; Nilsson K
    Adv Cancer Res; 2007; 97():139-65. PubMed ID: 17419944
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.