392 related articles for article (PubMed ID: 23515440)
1. A synthetic PPAR-γ agonist triterpenoid ameliorates experimental fibrosis: PPAR-γ-independent suppression of fibrotic responses.
Wei J; Zhu H; Komura K; Lord G; Tomcik M; Wang W; Doniparthi S; Tamaki Z; Hinchcliff M; Distler JH; Varga J
Ann Rheum Dis; 2014 Feb; 73(2):446-54. PubMed ID: 23515440
[TBL] [Abstract][Full Text] [Related]
2. The adipokine adiponectin has potent anti-fibrotic effects mediated via adenosine monophosphate-activated protein kinase: novel target for fibrosis therapy.
Fang F; Liu L; Yang Y; Tamaki Z; Wei J; Marangoni RG; Bhattacharyya S; Summer RS; Ye B; Varga J
Arthritis Res Ther; 2012 Oct; 14(5):R229. PubMed ID: 23092446
[TBL] [Abstract][Full Text] [Related]
3. Electrophilic peroxisome proliferator-activated receptor-gamma ligands have potent antifibrotic effects in human lung fibroblasts.
Ferguson HE; Kulkarni A; Lehmann GM; Garcia-Bates TM; Thatcher TH; Huxlin KR; Phipps RP; Sime PJ
Am J Respir Cell Mol Biol; 2009 Dec; 41(6):722-30. PubMed ID: 19286977
[TBL] [Abstract][Full Text] [Related]
4. Disruption of transforming growth factor beta signaling and profibrotic responses in normal skin fibroblasts by peroxisome proliferator-activated receptor gamma.
Ghosh AK; Bhattacharyya S; Lakos G; Chen SJ; Mori Y; Varga J
Arthritis Rheum; 2004 Apr; 50(4):1305-18. PubMed ID: 15077315
[TBL] [Abstract][Full Text] [Related]
5. PPARγ downregulation by TGFß in fibroblast and impaired expression and function in systemic sclerosis: a novel mechanism for progressive fibrogenesis.
Wei J; Ghosh AK; Sargent JL; Komura K; Wu M; Huang QQ; Jain M; Whitfield ML; Feghali-Bostwick C; Varga J
PLoS One; 2010 Nov; 5(11):e13778. PubMed ID: 21072170
[TBL] [Abstract][Full Text] [Related]
6. Rosiglitazone abrogates bleomycin-induced scleroderma and blocks profibrotic responses through peroxisome proliferator-activated receptor-gamma.
Wu M; Melichian DS; Chang E; Warner-Blankenship M; Ghosh AK; Varga J
Am J Pathol; 2009 Feb; 174(2):519-33. PubMed ID: 19147827
[TBL] [Abstract][Full Text] [Related]
7. Peroxisome proliferator-activated receptor-gamma-independent repression of collagenase gene expression by 2-cyano-3,12-dioxooleana-1,9-dien-28-oic acid and prostaglandin 15-deoxy-delta(12,14) J2: a role for Smad signaling.
Mix KS; Coon CI; Rosen ED; Suh N; Sporn MB; Brinckerhoff CE
Mol Pharmacol; 2004 Feb; 65(2):309-18. PubMed ID: 14742672
[TBL] [Abstract][Full Text] [Related]
8. Synthetic cannabinoid ajulemic acid exerts potent antifibrotic effects in experimental models of systemic sclerosis.
Gonzalez EG; Selvi E; Balistreri E; Akhmetshina A; Palumbo K; Lorenzini S; Lazzerini PE; Montilli C; Capecchi PL; Lucattelli M; Baldi C; Gianchecchi E; Galeazzi M; Pasini FL; Distler JH
Ann Rheum Dis; 2012 Sep; 71(9):1545-51. PubMed ID: 22492781
[TBL] [Abstract][Full Text] [Related]
9. Pan PPAR agonist IVA337 is effective in prevention and treatment of experimental skin fibrosis.
Ruzehaji N; Frantz C; Ponsoye M; Avouac J; Pezet S; Guilbert T; Luccarini JM; Broqua P; Junien JL; Allanore Y
Ann Rheum Dis; 2016 Dec; 75(12):2175-2183. PubMed ID: 26961294
[TBL] [Abstract][Full Text] [Related]
10. Scleroderma keratinocytes promote fibroblast activation independent of transforming growth factor beta.
McCoy SS; Reed TJ; Berthier CC; Tsou PS; Liu J; Gudjonsson JE; Khanna D; Kahlenberg JM
Rheumatology (Oxford); 2017 Nov; 56(11):1970-1981. PubMed ID: 28968684
[TBL] [Abstract][Full Text] [Related]
11. Vitamin D receptor regulates TGF-β signalling in systemic sclerosis.
Zerr P; Vollath S; Palumbo-Zerr K; Tomcik M; Huang J; Distler A; Beyer C; Dees C; Gela K; Distler O; Schett G; Distler JH
Ann Rheum Dis; 2015 Mar; 74(3):e20. PubMed ID: 24448349
[TBL] [Abstract][Full Text] [Related]
12. Heat shock protein 90 (Hsp90) inhibition targets canonical TGF-β signalling to prevent fibrosis.
Tomcik M; Zerr P; Pitkowski J; Palumbo-Zerr K; Avouac J; Distler O; Becvar R; Senolt L; Schett G; Distler JH
Ann Rheum Dis; 2014 Jun; 73(6):1215-22. PubMed ID: 23661493
[TBL] [Abstract][Full Text] [Related]
13. Toll-like receptor 4 signaling augments transforming growth factor-β responses: a novel mechanism for maintaining and amplifying fibrosis in scleroderma.
Bhattacharyya S; Kelley K; Melichian DS; Tamaki Z; Fang F; Su Y; Feng G; Pope RM; Budinger GR; Mutlu GM; Lafyatis R; Radstake T; Feghali-Bostwick C; Varga J
Am J Pathol; 2013 Jan; 182(1):192-205. PubMed ID: 23141927
[TBL] [Abstract][Full Text] [Related]
14. p300 is elevated in systemic sclerosis and its expression is positively regulated by TGF-β: epigenetic feed-forward amplification of fibrosis.
Ghosh AK; Bhattacharyya S; Lafyatis R; Farina G; Yu J; Thimmapaya B; Wei J; Varga J
J Invest Dermatol; 2013 May; 133(5):1302-10. PubMed ID: 23303459
[TBL] [Abstract][Full Text] [Related]
15. Loss of peroxisome proliferator-activated receptor gamma in mouse fibroblasts results in increased susceptibility to bleomycin-induced skin fibrosis.
Kapoor M; McCann M; Liu S; Huh K; Denton CP; Abraham DJ; Leask A
Arthritis Rheum; 2009 Sep; 60(9):2822-9. PubMed ID: 19714649
[TBL] [Abstract][Full Text] [Related]
16. The transcription factor GLI2 as a downstream mediator of transforming growth factor-β-induced fibroblast activation in SSc.
Liang R; Šumová B; Cordazzo C; Mallano T; Zhang Y; Wohlfahrt T; Dees C; Ramming A; Krasowska D; Michalska-Jakubus M; Distler O; Schett G; Šenolt L; Distler JH
Ann Rheum Dis; 2017 Apr; 76(4):756-764. PubMed ID: 27793816
[TBL] [Abstract][Full Text] [Related]
17. Sirt1 regulates canonical TGF-β signalling to control fibroblast activation and tissue fibrosis.
Zerr P; Palumbo-Zerr K; Huang J; Tomcik M; Sumova B; Distler O; Schett G; Distler JH
Ann Rheum Dis; 2016 Jan; 75(1):226-33. PubMed ID: 25180292
[TBL] [Abstract][Full Text] [Related]
18. Targeted disruption of TGF-beta/Smad3 signaling modulates skin fibrosis in a mouse model of scleroderma.
Lakos G; Takagawa S; Chen SJ; Ferreira AM; Han G; Masuda K; Wang XJ; DiPietro LA; Varga J
Am J Pathol; 2004 Jul; 165(1):203-17. PubMed ID: 15215176
[TBL] [Abstract][Full Text] [Related]
19. PPAR-γ ligands repress TGFβ-induced myofibroblast differentiation by targeting the PI3K/Akt pathway: implications for therapy of fibrosis.
Kulkarni AA; Thatcher TH; Olsen KC; Maggirwar SB; Phipps RP; Sime PJ
PLoS One; 2011 Jan; 6(1):e15909. PubMed ID: 21253589
[TBL] [Abstract][Full Text] [Related]
20. Proteasomal inhibition after injury prevents fibrosis by modulating TGF-β(1) signalling.
Mutlu GM; Budinger GR; Wu M; Lam AP; Zirk A; Rivera S; Urich D; Chiarella SE; Go LH; Ghosh AK; Selman M; Pardo A; Varga J; Kamp DW; Chandel NS; Sznajder JI; Jain M
Thorax; 2012 Feb; 67(2):139-46. PubMed ID: 21921091
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]