BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

196 related articles for article (PubMed ID: 23519665)

  • 1. Structural studies of Pseudomonas and Chromobacterium ω-aminotransferases provide insights into their differing substrate specificity.
    Sayer C; Isupov MN; Westlake A; Littlechild JA
    Acta Crystallogr D Biol Crystallogr; 2013 Apr; 69(Pt 4):564-76. PubMed ID: 23519665
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Crystal structures of the Chromobacterium violaceumω-transaminase reveal major structural rearrangements upon binding of coenzyme PLP.
    Humble MS; Cassimjee KE; Håkansson M; Kimbung YR; Walse B; Abedi V; Federsel HJ; Berglund P; Logan DT
    FEBS J; 2012 Mar; 279(5):779-92. PubMed ID: 22268978
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Crystal structure and substrate specificity of the thermophilic serine:pyruvate aminotransferase from Sulfolobus solfataricus.
    Sayer C; Bommer M; Isupov M; Ward J; Littlechild J
    Acta Crystallogr D Biol Crystallogr; 2012 Jul; 68(Pt 7):763-72. PubMed ID: 22751661
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Crystallization and preliminary X-ray diffraction analysis of omega-amino acid:pyruvate transaminase from Chromobacterium violaceum.
    Sayer C; Isupov MN; Littlechild JA
    Acta Crystallogr Sect F Struct Biol Cryst Commun; 2007 Feb; 63(Pt 2):117-9. PubMed ID: 17277454
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Biochemical properties of a Pseudomonas aminotransferase involved in caprolactam metabolism.
    Palacio CM; Rozeboom HJ; Lanfranchi E; Meng Q; Otzen M; Janssen DB
    FEBS J; 2019 Oct; 286(20):4086-4102. PubMed ID: 31162815
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The substrate specificity, enantioselectivity and structure of the (R)-selective amine : pyruvate transaminase from Nectria haematococca.
    Sayer C; Martinez-Torres RJ; Richter N; Isupov MN; Hailes HC; Littlechild JA; Ward JM
    FEBS J; 2014 May; 281(9):2240-53. PubMed ID: 24618038
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Structural and biochemical characterization of the dual substrate recognition of the (R)-selective amine transaminase from Aspergillus fumigatus.
    Skalden L; Thomsen M; Höhne M; Bornscheuer UT; Hinrichs W
    FEBS J; 2015 Jan; 282(2):407-15. PubMed ID: 25400251
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Structural Basis of the Substrate Range and Enantioselectivity of Two (S)-Selective ω-Transaminases.
    van Oosterwijk N; Willies S; Hekelaar J; Terwisscha van Scheltinga AC; Turner NJ; Dijkstra BW
    Biochemistry; 2016 Aug; 55(31):4422-31. PubMed ID: 27428867
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Human ornithine aminotransferase complexed with L-canaline and gabaculine: structural basis for substrate recognition.
    Shah SA; Shen BW; Brünger AT
    Structure; 1997 Aug; 5(8):1067-75. PubMed ID: 9309222
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Insight into the dimer dissociation process of the Chromobacterium violaceum (S)-selective amine transaminase.
    Ruggieri F; Campillo-Brocal JC; Chen S; Humble MS; Walse B; Logan DT; Berglund P
    Sci Rep; 2019 Nov; 9(1):16946. PubMed ID: 31740704
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Structural characterization of a 2-aminoethylphosphonate:pyruvate aminotransferase from Pseudomonas aeruginosa PAO1.
    Jia H; Chen Y; Chen Y; Liu R; Zhang Q; Bartlam M
    Biochem Biophys Res Commun; 2021 May; 552():114-119. PubMed ID: 33743347
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Single active-site mutants are sufficient to enhance serine:pyruvate α-transaminase activity in an ω-transaminase.
    Deszcz D; Affaticati P; Ladkau N; Gegel A; Ward JM; Hailes HC; Dalby PA
    FEBS J; 2015 Jul; 282(13):2512-26. PubMed ID: 25846556
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The structure of LL-diaminopimelate aminotransferase from Chlamydia trachomatis: implications for its broad substrate specificity.
    Watanabe N; Clay MD; van Belkum MJ; Fan C; Vederas JC; James MN
    J Mol Biol; 2011 Aug; 411(3):649-60. PubMed ID: 21722650
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Chromobacterium violaceum ω-transaminase variant Trp60Cys shows increased specificity for (S)-1-phenylethylamine and 4'-substituted acetophenones, and follows Swain-Lupton parameterisation.
    Cassimjee KE; Humble MS; Land H; Abedi V; Berglund P
    Org Biomol Chem; 2012 Jul; 10(28):5466-70. PubMed ID: 22688085
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Biochemical and structural characterization of a highly active branched-chain amino acid aminotransferase from Pseudomonas sp. for efficient biosynthesis of chiral amino acids.
    Zheng X; Cui Y; Li T; Li R; Guo L; Li D; Wu B
    Appl Microbiol Biotechnol; 2019 Oct; 103(19):8051-8062. PubMed ID: 31485690
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Structural Determinants of the Stereoinverting Activity of Pseudomonas stutzeri d-Phenylglycine Aminotransferase.
    Walton CJW; Thiebaut F; Brunzelle JS; Couture JF; Chica RA
    Biochemistry; 2018 Sep; 57(37):5437-5446. PubMed ID: 30153007
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The crystal structure of the tetrameric DABA-aminotransferase EctB, a rate-limiting enzyme in the ectoine biosynthesis pathway.
    Hillier HT; Altermark B; Leiros I
    FEBS J; 2020 Nov; 287(21):4641-4658. PubMed ID: 32112674
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Structural insights into the enzyme specificity of a novel ω-transaminase from the thermophilic bacterium Sphaerobacter thermophilus.
    Kwon S; Lee JH; Kim CM; Ha HJ; Lee SH; Lee CS; Jeon JH; So I; Park HH
    J Struct Biol; 2019 Dec; 208(3):107395. PubMed ID: 31560999
    [TBL] [Abstract][Full Text] [Related]  

  • 19. 1.2 Å resolution crystal structure of the periplasmic aminotransferase PvdN from Pseudomonas aeruginosa.
    Drake EJ; Gulick AM
    Acta Crystallogr F Struct Biol Commun; 2016 May; 72(Pt 5):403-8. PubMed ID: 27139833
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Microscale methods to rapidly evaluate bioprocess options for increasing bioconversion yields: application to the ω-transaminase synthesis of chiral amines.
    Halim M; Rios-Solis L; Micheletti M; Ward JM; Lye GJ
    Bioprocess Biosyst Eng; 2014 May; 37(5):931-41. PubMed ID: 24078149
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.