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10. Combining mutations that modulate inter-subunit interactions and proteolytic inactivation enhance the stability of factor VIIIa. Wakabayashi H; Wintermute JM; Fay PJ Thromb Haemost; 2014 Jul; 112(1):43-52. PubMed ID: 24599523 [TBL] [Abstract][Full Text] [Related]
11. Hemophilia A mutations associated with 1-stage/2-stage activity discrepancy disrupt protein-protein interactions within the triplicated A domains of thrombin-activated factor VIIIa. Pipe SW; Saenko EL; Eickhorst AN; Kemball-Cook G; Kaufman RJ Blood; 2001 Feb; 97(3):685-91. PubMed ID: 11157485 [TBL] [Abstract][Full Text] [Related]
12. Contribution of factor VIII light-chain residues 2007-2016 to an activated protein C-interactive site. Takeyama M; Wakabayashi H; Fay PJ Thromb Haemost; 2013 Feb; 109(2):187-98. PubMed ID: 23224054 [TBL] [Abstract][Full Text] [Related]
13. Hemophilia A mutations within the factor VIII A2-A3 subunit interface destabilize factor VIIIa and cause one-stage/two-stage activity discrepancy. Hakeos WH; Miao H; Sirachainan N; Kemball-Cook G; Saenko EL; Kaufman RJ; Pipe SW Thromb Haemost; 2002 Nov; 88(5):781-7. PubMed ID: 12428094 [TBL] [Abstract][Full Text] [Related]
14. Computational analysis of Asp519 and Glu665 mutations of coagulation factor FVIIIa: Implications for enhanced binding affinity of A2-domain. Shearin S; Venkateswarlu D J Mol Graph Model; 2017 Sep; 76():441-447. PubMed ID: 28780303 [TBL] [Abstract][Full Text] [Related]
15. A3 domain region 1803-1818 contributes to the stability of activated factor VIII and includes a binding site for activated factor IX. Bloem E; Meems H; van den Biggelaar M; Mertens K; Meijer AB J Biol Chem; 2013 Sep; 288(36):26105-26111. PubMed ID: 23884417 [TBL] [Abstract][Full Text] [Related]
16. The factor VIIIa C2 domain (residues 2228-2240) interacts with the factor IXa Gla domain in the factor Xase complex. Soeda T; Nogami K; Nishiya K; Takeyama M; Ogiwara K; Sakata Y; Yoshioka A; Shima M J Biol Chem; 2009 Feb; 284(6):3379-88. PubMed ID: 19047063 [TBL] [Abstract][Full Text] [Related]
17. Contribution of A1 subunit residue Q316 in thrombin-activated factor VIII to A2 subunit dissociation. Parker ET; Lollar P Biochemistry; 2007 Aug; 46(34):9737-42. PubMed ID: 17676877 [TBL] [Abstract][Full Text] [Related]
19. Mutations associated with hemophilia A in the 558-565 loop of the factor VIIIa A2 subunit alter the catalytic activity of the factor Xase complex. Jenkins PV; Freas J; Schmidt KM; Zhou Q; Fay PJ Blood; 2002 Jul; 100(2):501-8. PubMed ID: 12091341 [TBL] [Abstract][Full Text] [Related]
20. Modification of interdomain interfaces within the A3C1C2 subunit of factor VIII affects its stability and activity. Wakabayashi H; Fay PJ Biochemistry; 2013 Jun; 52(22):3921-9. PubMed ID: 23659383 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]