BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

405 related articles for article (PubMed ID: 23523371)

  • 1. Nkx2-1 represses a latent gastric differentiation program in lung adenocarcinoma.
    Snyder EL; Watanabe H; Magendantz M; Hoersch S; Chen TA; Wang DG; Crowley D; Whittaker CA; Meyerson M; Kimura S; Jacks T
    Mol Cell; 2013 Apr; 50(2):185-99. PubMed ID: 23523371
    [TBL] [Abstract][Full Text] [Related]  

  • 2. FoxA1 and FoxA2 drive gastric differentiation and suppress squamous identity in NKX2-1-negative lung cancer.
    Camolotto SA; Pattabiraman S; Mosbruger TL; Jones A; Belova VK; Orstad G; Streiff M; Salmond L; Stubben C; Kaestner KH; Snyder EL
    Elife; 2018 Nov; 7():. PubMed ID: 30475207
    [TBL] [Abstract][Full Text] [Related]  

  • 3. KRAS and NKX2-1 Mutations in Invasive Mucinous Adenocarcinoma of the Lung.
    Hwang DH; Sholl LM; Rojas-Rudilla V; Hall DL; Shivdasani P; Garcia EP; MacConaill LE; Vivero M; Hornick JL; Kuo FC; Lindeman NI; Dong F
    J Thorac Oncol; 2016 Apr; 11(4):496-503. PubMed ID: 26829311
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Kras(G12D) and Nkx2-1 haploinsufficiency induce mucinous adenocarcinoma of the lung.
    Maeda Y; Tsuchiya T; Hao H; Tompkins DH; Xu Y; Mucenski ML; Du L; Keiser AR; Fukazawa T; Naomoto Y; Nagayasu T; Whitsett JA
    J Clin Invest; 2012 Dec; 122(12):4388-400. PubMed ID: 23143308
    [TBL] [Abstract][Full Text] [Related]  

  • 5. FoxA1 and FoxA2 control growth and cellular identity in NKX2-1-positive lung adenocarcinoma.
    Orstad G; Fort G; Parnell TJ; Jones A; Stubben C; Lohman B; Gillis KL; Orellana W; Tariq R; Klingbeil O; Kaestner K; Vakoc CR; Spike BT; Snyder EL
    Dev Cell; 2022 Aug; 57(15):1866-1882.e10. PubMed ID: 35835117
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Foxa2 and Cdx2 cooperate with Nkx2-1 to inhibit lung adenocarcinoma metastasis.
    Li CM; Gocheva V; Oudin MJ; Bhutkar A; Wang SY; Date SR; Ng SR; Whittaker CA; Bronson RT; Snyder EL; Gertler FB; Jacks T
    Genes Dev; 2015 Sep; 29(17):1850-62. PubMed ID: 26341558
    [TBL] [Abstract][Full Text] [Related]  

  • 7. An NKX2-1/ERK/WNT feedback loop modulates gastric identity and response to targeted therapy in lung adenocarcinoma.
    Zewdu R; Mehrabad EM; Ingram K; Fang P; Gillis KL; Camolotto SA; Orstad G; Jones A; Mendoza MC; Spike BT; Snyder EL
    Elife; 2021 Apr; 10():. PubMed ID: 33821796
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The complexity of thyroid transcription factor 1 with both pro- and anti-oncogenic activities.
    Mu D
    J Biol Chem; 2013 Aug; 288(35):24992-25000. PubMed ID: 23818522
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Thyroid transcription factor-1-regulated microRNA-532-5p targets KRAS and MKL2 oncogenes and induces apoptosis in lung adenocarcinoma cells.
    Griesing S; Kajino T; Tai MC; Liu Z; Nakatochi M; Shimada Y; Suzuki M; Takahashi T
    Cancer Sci; 2017 Jul; 108(7):1394-1404. PubMed ID: 28474808
    [TBL] [Abstract][Full Text] [Related]  

  • 10. LKB1 loss by alteration of the NKX2-1/p53 pathway promotes tumor malignancy and predicts poor survival and relapse in lung adenocarcinomas.
    Tsai LH; Chen PM; Cheng YW; Chen CY; Sheu GT; Wu TC; Lee H
    Oncogene; 2014 Jul; 33(29):3851-60. PubMed ID: 23995788
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The predominant expression of hepatocyte nuclear factor 4α (HNF4α) in thyroid transcription factor-1 (TTF-1)-negative pulmonary adenocarcinoma.
    Kunii R; Jiang S; Hasegawa G; Yamamoto T; Umezu H; Watanabe T; Tsuchida M; Hashimoto T; Hamakubo T; Kodama T; Sasai K; Naito M
    Histopathology; 2011 Feb; 58(3):467-76. PubMed ID: 21348892
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Airway epithelial transcription factor NK2 homeobox 1 inhibits mucous cell metaplasia and Th2 inflammation.
    Maeda Y; Chen G; Xu Y; Haitchi HM; Du L; Keiser AR; Howarth PH; Davies DE; Holgate ST; Whitsett JA
    Am J Respir Crit Care Med; 2011 Aug; 184(4):421-9. PubMed ID: 21562130
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Suppression of lung adenocarcinoma progression by Nkx2-1.
    Winslow MM; Dayton TL; Verhaak RG; Kim-Kiselak C; Snyder EL; Feldser DM; Hubbard DD; DuPage MJ; Whittaker CA; Hoersch S; Yoon S; Crowley D; Bronson RT; Chiang DY; Meyerson M; Jacks T
    Nature; 2011 May; 473(7345):101-4. PubMed ID: 21471965
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Integrated cistromic and expression analysis of amplified NKX2-1 in lung adenocarcinoma identifies LMO3 as a functional transcriptional target.
    Watanabe H; Francis JM; Woo MS; Etemad B; Lin W; Fries DF; Peng S; Snyder EL; Tata PR; Izzo F; Schinzel AC; Cho J; Hammerman PS; Verhaak RG; Hahn WC; Rajagopal J; Jacks T; Meyerson M
    Genes Dev; 2013 Jan; 27(2):197-210. PubMed ID: 23322301
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Physical and functional interactions between homeodomain NKX2.1 and winged helix/forkhead FOXA1 in lung epithelial cells.
    Minoo P; Hu L; Xing Y; Zhu NL; Chen H; Li M; Borok Z; Li C
    Mol Cell Biol; 2007 Mar; 27(6):2155-65. PubMed ID: 17220277
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Inactivating mutations and hypermethylation of the NKX2-1/TTF-1 gene in non-terminal respiratory unit-type lung adenocarcinomas.
    Matsubara D; Soda M; Yoshimoto T; Amano Y; Sakuma Y; Yamato A; Ueno T; Kojima S; Shibano T; Hosono Y; Kawazu M; Yamashita Y; Endo S; Hagiwara K; Fukayama M; Takahashi T; Mano H; Niki T
    Cancer Sci; 2017 Sep; 108(9):1888-1896. PubMed ID: 28677170
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Nkx2-1: a novel tumor biomarker of lung cancer.
    Yang L; Lin M; Ruan WJ; Dong LL; Chen EG; Wu XH; Ying KJ
    J Zhejiang Univ Sci B; 2012 Nov; 13(11):855-66. PubMed ID: 23125078
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Neuroendocrine differentiation in the 12T-10 transgenic prostate mouse model mimics endocrine differentiation of pancreatic beta cells.
    Gupta A; Wang Y; Browne C; Kim S; Case T; Paul M; Wills ML; Matusik RJ
    Prostate; 2008 Jan; 68(1):50-60. PubMed ID: 18004726
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Genome-wide analyses of Nkx2-1 binding to transcriptional target genes uncover novel regulatory patterns conserved in lung development and tumors.
    Tagne JB; Gupta S; Gower AC; Shen SS; Varma S; Lakshminarayanan M; Cao Y; Spira A; Volkert TL; Ramirez MI
    PLoS One; 2012; 7(1):e29907. PubMed ID: 22242187
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Compensatory roles of Foxa1 and Foxa2 during lung morphogenesis.
    Wan H; Dingle S; Xu Y; Besnard V; Kaestner KH; Ang SL; Wert S; Stahlman MT; Whitsett JA
    J Biol Chem; 2005 Apr; 280(14):13809-16. PubMed ID: 15668254
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 21.