73 related articles for article (PubMed ID: 23528297)
1. A thiocarbamate inhibitor of endothelial lipase raises HDL cholesterol levels in mice.
Greco MN; Connelly MA; Leo GC; Olson MW; Powell E; Huang Z; Hawkins M; Smith C; Schalk-Hihi C; Darrow AL; Xin H; Lang W; Damiano BP; Hlasta DJ
Bioorg Med Chem Lett; 2013 May; 23(9):2595-7. PubMed ID: 23528297
[TBL] [Abstract][Full Text] [Related]
2. Discovery of XEN445: a potent and selective endothelial lipase inhibitor raises plasma HDL-cholesterol concentration in mice.
Sun S; Dean R; Jia Q; Zenova A; Zhong J; Grayson C; Xie C; Lindgren A; Samra P; Sojo L; van Heek M; Lin L; Percival D; Fu JM; Winther MD; Zhang Z
Bioorg Med Chem; 2013 Dec; 21(24):7724-34. PubMed ID: 24211162
[TBL] [Abstract][Full Text] [Related]
3. A novel endothelial-derived lipase that modulates HDL metabolism.
Jaye M; Lynch KJ; Krawiec J; Marchadier D; Maugeais C; Doan K; South V; Amin D; Perrone M; Rader DJ
Nat Genet; 1999 Apr; 21(4):424-8. PubMed ID: 10192396
[TBL] [Abstract][Full Text] [Related]
4. Update on the role of endothelial lipase in high-density lipoprotein metabolism, reverse cholesterol transport, and atherosclerosis.
Yasuda T; Ishida T; Rader DJ
Circ J; 2010 Nov; 74(11):2263-70. PubMed ID: 20962428
[TBL] [Abstract][Full Text] [Related]
5. Differential additive effects of endothelial lipase and scavenger receptor-class B type I on high-density lipoprotein metabolism in knockout mouse models.
Ma K; Forte T; Otvos JD; Chan L
Arterioscler Thromb Vasc Biol; 2005 Jan; 25(1):149-54. PubMed ID: 15539616
[TBL] [Abstract][Full Text] [Related]
6. Structure-reactivity relationships for the inhibition mechanism at the second alkyl-chain-binding site of cholesterol esterase and lipase.
Lin G; Shieh CT; Ho HC; Chouhwang JY; Lin WY; Lu CP
Biochemistry; 1999 Aug; 38(31):9971-81. PubMed ID: 10433704
[TBL] [Abstract][Full Text] [Related]
7. Identification of Reversible Small Molecule Inhibitors of Endothelial Lipase (EL) That Demonstrate HDL-C Increase In Vivo.
Tora G; Kim SH; Pi Z; Johnson JA; Jiang J; Phillips M; Lloyd J; Abell LM; Lu H; Locke G; Adam LP; Taylor DS; Yin X; Behnia K; Zhao L; Yang R; Basso M; Caporuscio C; Chen AY; Liu E; Kirshgessner T; Onorato JM; Ryan C; Traeger SC; Gordon D; Wexler RR; Finlay HJ
J Med Chem; 2020 Feb; 63(4):1660-1670. PubMed ID: 31990537
[TBL] [Abstract][Full Text] [Related]
8. Discovery and synthesis of tetrahydropyrimidinedione-4-carboxamides as endothelial lipase inhibitors.
Hu CH; Wang TC; Qiao JX; Haque L; Chen AYA; Taylor DS; Ying X; Onorato JM; Galella M; Shen H; Huang CS; Toussaint N; Li YX; Abell L; Adam LP; Gordon D; Wexler RR; Finlay HJ
Bioorg Med Chem Lett; 2018 Dec; 28(23-24):3721-3725. PubMed ID: 30348490
[TBL] [Abstract][Full Text] [Related]
9. Inhibition of endothelial lipase causes increased HDL cholesterol levels in vivo.
Jin W; Millar JS; Broedl U; Glick JM; Rader DJ
J Clin Invest; 2003 Feb; 111(3):357-62. PubMed ID: 12569161
[TBL] [Abstract][Full Text] [Related]
10. Angiopoietin-like protein3 regulates plasma HDL cholesterol through suppression of endothelial lipase.
Shimamura M; Matsuda M; Yasumo H; Okazaki M; Fujimoto K; Kono K; Shimizugawa T; Ando Y; Koishi R; Kohama T; Sakai N; Kotani K; Komuro R; Ishida T; Hirata K; Yamashita S; Furukawa H; Shimomura I
Arterioscler Thromb Vasc Biol; 2007 Feb; 27(2):366-72. PubMed ID: 17110602
[TBL] [Abstract][Full Text] [Related]
11. Endothelial lipase is a major determinant of HDL level.
Ishida T; Choi S; Kundu RK; Hirata K; Rubin EM; Cooper AD; Quertermous T
J Clin Invest; 2003 Feb; 111(3):347-55. PubMed ID: 12569160
[TBL] [Abstract][Full Text] [Related]
12. Benzothiazole-based compounds as potent endothelial lipase inhibitors.
Meng W; Adam LP; Behnia K; Zhao L; Yang R; Kopcho LM; Locke GA; Taylor DS; Yin X; Wexler RR; Finlay H
Bioorg Med Chem Lett; 2019 Oct; 29(20):126673. PubMed ID: 31519373
[TBL] [Abstract][Full Text] [Related]
13. A high-throughput screen for endothelial lipase using HDL as substrate.
Keller PM; Rust T; Murphy DJ; Matico R; Trill JJ; Krawiec JA; Jurewicz A; Jaye M; Harpel M; Thrall S; Schwartz B
J Biomol Screen; 2008 Jul; 13(6):468-75. PubMed ID: 18566479
[TBL] [Abstract][Full Text] [Related]
14. Targeted deletion of endothelial lipase increases HDL particles with anti-inflammatory properties both in vitro and in vivo.
Hara T; Ishida T; Kojima Y; Tanaka H; Yasuda T; Shinohara M; Toh R; Hirata K
J Lipid Res; 2011 Jan; 52(1):57-67. PubMed ID: 20926433
[TBL] [Abstract][Full Text] [Related]
15. Hepatic proprotein convertases modulate HDL metabolism.
Jin W; Wang X; Millar JS; Quertermous T; Rothblat GH; Glick JM; Rader DJ
Cell Metab; 2007 Aug; 6(2):129-36. PubMed ID: 17681148
[TBL] [Abstract][Full Text] [Related]
16. [The role of endothelial lipase in atherogenesis].
Pierart Z C; Serrano L V
Rev Med Chil; 2012 Mar; 140(3):373-8. PubMed ID: 22689120
[TBL] [Abstract][Full Text] [Related]
17. Discovery of potent, selective sulfonylfuran urea endothelial lipase inhibitors.
Goodman KB; Bury MJ; Cheung M; Cichy-Knight MA; Dowdell SE; Dunn AK; Lee D; Lieby JA; Moore ML; Scherzer DA; Sha D; Suarez DP; Murphy DJ; Harpel MR; Manas ES; McNulty DE; Annan RS; Matico RE; Schwartz BK; Trill JJ; Sweitzer TD; Wang DY; Keller PM; Krawiec JA; Jaye MC
Bioorg Med Chem Lett; 2009 Jan; 19(1):27-30. PubMed ID: 19058966
[TBL] [Abstract][Full Text] [Related]
18. Hepatic lipase gene therapy in hepatic lipase-deficient mice. Adenovirus-mediated replacement of a lipolytic enzyme to the vascular endothelium.
Applebaum-Bowden D; Kobayashi J; Kashyap VS; Brown DR; Berard A; Meyn S; Parrott C; Maeda N; Shamburek R; Brewer HB; Santamarina-Fojo S
J Clin Invest; 1996 Feb; 97(3):799-805. PubMed ID: 8609237
[TBL] [Abstract][Full Text] [Related]
19. Nascent HDL formation by hepatocytes is reduced by the concerted action of serum amyloid A and endothelial lipase.
Wroblewski JM; Jahangiri A; Ji A; de Beer FC; van der Westhuyzen DR; Webb NR
J Lipid Res; 2011 Dec; 52(12):2255-2261. PubMed ID: 21957202
[TBL] [Abstract][Full Text] [Related]
20. Design and synthesis of boronic acid inhibitors of endothelial lipase.
O'Connell DP; LeBlanc DF; Cromley D; Billheimer J; Rader DJ; Bachovchin WW
Bioorg Med Chem Lett; 2012 Feb; 22(3):1397-401. PubMed ID: 22225633
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
