BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

127 related articles for article (PubMed ID: 23535327)

  • 1. Synthesis and structure-activity relationship of pyripyropene A derivatives as potent and selective acyl-CoA:cholesterol acyltransferase 2 (ACAT2) inhibitors: part 2.
    Ohtawa M; Yamazaki H; Matsuda D; Ohshiro T; Rudel LL; Ōmura S; Tomoda H; Nagamitsu T
    Bioorg Med Chem Lett; 2013 May; 23(9):2659-62. PubMed ID: 23535327
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Synthesis and structure-activity relationship of pyripyropene A derivatives as potent and selective acyl-CoA:cholesterol acyltransferase 2 (ACAT2) inhibitors: part 3.
    Ohtawa M; Yamazaki H; Ohte S; Matsuda D; Ohshiro T; Rudel LL; Ōmura S; Tomoda H; Nagamitsu T
    Bioorg Med Chem Lett; 2013 Jul; 23(13):3798-801. PubMed ID: 23711919
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Synthesis and structure-activity relationship of pyripyropene A derivatives as potent and selective acyl-CoA:cholesterol acyltransferase 2 (ACAT2) inhibitors: part 1.
    Ohtawa M; Yamazaki H; Ohte S; Matsuda D; Ohshiro T; Rudel LL; Omura S; Tomoda H; Nagamitsu T
    Bioorg Med Chem Lett; 2013 Mar; 23(5):1285-7. PubMed ID: 23369538
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Design and synthesis of simple, yet potent and selective non-ring-A pyripyropene A-based inhibitors of acyl-coenzyme A: cholesterol acyltransferase 2 (ACAT2).
    Zhan Y; Zhang XW; Xiong Y; Li BL; Nan FJ
    Org Biomol Chem; 2016 Jan; 14(2):747-751. PubMed ID: 26584338
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Penicillium griseofulvum F1959, high-production strain of pyripyropene a, specific inhibitor of acyl-CoA: cholesterol acyltransferase 2.
    Choi JH; Rho MC; Lee SW; Choi JN; Lee HJ; Bae KS; Kim K; Kim YK
    J Microbiol Biotechnol; 2008 Oct; 18(10):1663-5. PubMed ID: 18955816
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Selectivity of pyripyropene derivatives in inhibition toward acyl-CoA:cholesterol acyltransferase 2 isozyme.
    Ohshiro T; Ohte S; Matsuda D; Ohtawa M; Nagamitsu T; Sunazuka T; Harigaya Y; Rudel LL; Omura S; Tomoda H
    J Antibiot (Tokyo); 2008 Aug; 61(8):503-8. PubMed ID: 18997389
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Chemical modification and structure-activity relationships of pyripyropenes. 3. Synthetic conversion of pyridine-pyrone moiety.
    Obata R; Sunazuka T; Tian Z; Tomoda H; Harigaya Y; Omura S
    J Antibiot (Tokyo); 1997 Mar; 50(3):229-36. PubMed ID: 9127194
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Design and Synthesis of A-Ring Simplified Pyripyropene A Analogues as Potent and Selective Synthetic SOAT2 Inhibitors.
    Ohtawa M; Arima S; Ichida N; Terayama T; Ohno H; Yamazaki T; Ohshiro T; Sato N; Omura S; Tomoda H; Nagamitsu T
    ChemMedChem; 2018 Mar; 13(5):411-421. PubMed ID: 29323466
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Chemical modification and structure-activity relationships of pyripyropenes. 2. 1,11-Cyclic analogs.
    Obata R; Sunazuka T; Kato Y; Tomoda H; Harigaya Y; Omura S
    J Antibiot (Tokyo); 1996 Nov; 49(11):1149-56. PubMed ID: 8982344
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Total synthesis of alpha-pyrone meroterpenoids, novel bioactive microbial metabolites.
    Sunazuka T; Omura S
    Chem Rev; 2005 Dec; 105(12):4559-80. PubMed ID: 16351054
    [No Abstract]   [Full Text] [Related]  

  • 11. New pyripyropene A derivatives, highly SOAT2-selective inhibitors, improve hypercholesterolemia and atherosclerosis in atherogenic mouse models.
    Ohshiro T; Ohtawa M; Nagamitsu T; Matsuda D; Yagyu H; Davis MA; Rudel LL; Ishibashi S; Tomoda H
    J Pharmacol Exp Ther; 2015 Nov; 355(2):299-307. PubMed ID: 26338984
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Pyripyropenes, novel ACAT inhibitors produced by Aspergillus fumigatus. IV. Structure elucidation of pyripyropenes M to R.
    Tomoda H; Tabata N; Yang DJ; Namatame I; Tanaka H; Omura S; Kaneko T
    J Antibiot (Tokyo); 1996 Mar; 49(3):292-8. PubMed ID: 8626247
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Synthesis and structure-activity relationship studies on a novel series of naphthylidinoylureas as inhibitors of acyl-CoA:cholesterol O-acyltransferase (ACAT).
    Ohnuma S; Muraoka M; Ioriya K; Ohashi N
    Bioorg Med Chem Lett; 2004 Mar; 14(5):1309-11. PubMed ID: 14980688
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Pyripyropene A, an acyl-coenzyme A:cholesterol acyltransferase 2-selective inhibitor, attenuates hypercholesterolemia and atherosclerosis in murine models of hyperlipidemia.
    Ohshiro T; Matsuda D; Sakai K; Degirolamo C; Yagyu H; Rudel LL; Omura S; Ishibashi S; Tomoda H
    Arterioscler Thromb Vasc Biol; 2011 May; 31(5):1108-15. PubMed ID: 21393580
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Selectivity of microbial acyl-CoA: cholesterol acyltransferase inhibitors toward isozymes.
    Ohshiro T; Rudel LL; Omura S; Tomoda H
    J Antibiot (Tokyo); 2007 Jan; 60(1):43-51. PubMed ID: 17390588
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Discovery and combinatorial synthesis of fungal metabolites beauveriolides, novel antiatherosclerotic agents.
    Tomoda H; Doi T
    Acc Chem Res; 2008 Jan; 41(1):32-9. PubMed ID: 17803269
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Structure-activity relationships of pyripyropenes fungal acyl-CoA: cholesterol acyltransferase inhibitors.
    Obata R; Sunazuka T; Li Z; Tomoda H; Omura S
    J Antibiot (Tokyo); 1995 Jul; 48(7):749-50. PubMed ID: 7649883
    [No Abstract]   [Full Text] [Related]  

  • 18. Novel 3,5-diaryl pyrazolines as human acyl-CoA:cholesterol acyltransferase inhibitors.
    Jeong TS; Kim KS; An S; Cho KH; Lee S; Lee WS
    Bioorg Med Chem Lett; 2004 Jun; 14(11):2715-7. PubMed ID: 15125920
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Pyripyropenes, novel inhibitors of acyl-CoA:cholesterol acyltransferase produced by Aspergillus fumigatus. II. Structure elucidation of pyripyropenes A, B, C and D.
    Kim YK; Tomoda H; Nishida H; Sunazuka T; Obata R; Omura S
    J Antibiot (Tokyo); 1994 Feb; 47(2):154-62. PubMed ID: 8150710
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Chemical modification and structure-activity relationships of pyripyropenes. 1. Modification at the four hydroxyl groups.
    Obata R; Sunazuka T; Li Z; Tian Z; Harigaya Y; Tabata N; Tomoda H; Omura S
    J Antibiot (Tokyo); 1996 Nov; 49(11):1133-48. PubMed ID: 8982343
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.