BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

209 related articles for article (PubMed ID: 23536552)

  • 1. High-throughput tyrosine kinase activity profiling identifies FAK as a candidate therapeutic target in Ewing sarcoma.
    Crompton BD; Carlton AL; Thorner AR; Christie AL; Du J; Calicchio ML; Rivera MN; Fleming MD; Kohl NE; Kung AL; Stegmaier K
    Cancer Res; 2013 May; 73(9):2873-83. PubMed ID: 23536552
    [TBL] [Abstract][Full Text] [Related]  

  • 2. High-throughput Chemical Screening Identifies Focal Adhesion Kinase and Aurora Kinase B Inhibition as a Synergistic Treatment Combination in Ewing Sarcoma.
    Wang S; Hwang EE; Guha R; O'Neill AF; Melong N; Veinotte CJ; Conway Saur A; Wuerthele K; Shen M; McKnight C; Alexe G; Lemieux ME; Wang A; Hughes E; Xu X; Boxer MB; Hall MD; Kung A; Berman JN; Davis MI; Stegmaier K; Crompton BD
    Clin Cancer Res; 2019 Jul; 25(14):4552-4566. PubMed ID: 30979745
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Focal adhesion kinase confers pro-migratory and antiapoptotic properties and is a potential therapeutic target in Ewing sarcoma.
    Steinestel K; Trautmann M; Jansen EP; Dirksen U; Rehkämper J; Mikesch JH; Gerke JS; Orth MF; Sannino G; Arteaga MF; Rossig C; Wardelmann E; Grünewald TGP; Hartmann W
    Mol Oncol; 2020 Feb; 14(2):248-260. PubMed ID: 31811703
    [TBL] [Abstract][Full Text] [Related]  

  • 4. TAE226, a dual inhibitor of focal adhesion kinase and insulin-like growth factor-I receptor, is effective for Ewing sarcoma.
    Moritake H; Saito Y; Sawa D; Sameshima N; Yamada A; Kinoshita M; Kamimura S; Konomoto T; Nunoi H
    Cancer Med; 2019 Dec; 8(18):7809-7821. PubMed ID: 31692287
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Antitumor activity and pharmacology of a selective focal adhesion kinase inhibitor, PF-562,271.
    Roberts WG; Ung E; Whalen P; Cooper B; Hulford C; Autry C; Richter D; Emerson E; Lin J; Kath J; Coleman K; Yao L; Martinez-Alsina L; Lorenzen M; Berliner M; Luzzio M; Patel N; Schmitt E; LaGreca S; Jani J; Wessel M; Marr E; Griffor M; Vajdos F
    Cancer Res; 2008 Mar; 68(6):1935-44. PubMed ID: 18339875
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Focal adhesion kinase is redistributed to focal complexes and mediates cell spreading in macrophages in response to M-CSF.
    Rovida E; Lugli B; Barbetti V; Giuntoli S; Olivotto M; Dello Sbarba P
    Biol Chem; 2005 Sep; 386(9):919-29. PubMed ID: 16164417
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Staurosporine induces endothelial cell apoptosis via focal adhesion kinase dephosphorylation and focal adhesion disassembly independent of focal adhesion kinase proteolysis.
    Kabir J; Lobo M; Zachary I
    Biochem J; 2002 Oct; 367(Pt 1):145-55. PubMed ID: 12084011
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Dasatinib inhibits migration and invasion in diverse human sarcoma cell lines and induces apoptosis in bone sarcoma cells dependent on SRC kinase for survival.
    Shor AC; Keschman EA; Lee FY; Muro-Cacho C; Letson GD; Trent JC; Pledger WJ; Jove R
    Cancer Res; 2007 Mar; 67(6):2800-8. PubMed ID: 17363602
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Targeting the EWSR1-FLI1 oncogene-induced protein kinase PKC-β abolishes ewing sarcoma growth.
    Surdez D; Benetkiewicz M; Perrin V; Han ZY; Pierron G; Ballet S; Lamoureux F; Rédini F; Decouvelaere AV; Daudigeos-Dubus E; Geoerger B; de Pinieux G; Delattre O; Tirode F
    Cancer Res; 2012 Sep; 72(17):4494-503. PubMed ID: 22930730
    [TBL] [Abstract][Full Text] [Related]  

  • 10. [RNA interference targeting focal adhesion kinase inhibited the growth of human hepatocellular carcinoma sk-hep-1].
    Xu WJ; Zhang S; Zhang N; Yang Y; Wei YQ; Deng HX
    Sichuan Da Xue Xue Bao Yi Xue Ban; 2011 Jul; 42(4):455-60. PubMed ID: 21866625
    [TBL] [Abstract][Full Text] [Related]  

  • 11. TAE226-induced apoptosis in breast cancer cells with overexpressed Src or EGFR.
    Golubovskaya VM; Virnig C; Cance WG
    Mol Carcinog; 2008 Mar; 47(3):222-34. PubMed ID: 17849451
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Functional analysis of focal adhesion kinase (FAK) reduction by small inhibitory RNAs.
    Han EK; Mcgonigal T; Wang J; Giranda VL; Luo Y
    Anticancer Res; 2004; 24(6):3899-905. PubMed ID: 15736429
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Simultaneous inhibition of focal adhesion kinase and SRC enhances detachment and apoptosis in colon cancer cell lines.
    Golubovskaya VM; Gross S; Kaur AS; Wilson RI; Xu LH; Yang XH; Cance WG
    Mol Cancer Res; 2003 Aug; 1(10):755-64. PubMed ID: 12939401
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Intrinsic FAK activity and Y925 phosphorylation facilitate an angiogenic switch in tumors.
    Mitra SK; Mikolon D; Molina JE; Hsia DA; Hanson DA; Chi A; Lim ST; Bernard-Trifilo JA; Ilic D; Stupack DG; Cheresh DA; Schlaepfer DD
    Oncogene; 2006 Sep; 25(44):5969-84. PubMed ID: 16682956
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Tyrosine phosphorylation and activation of focal adhesion kinase (p125FAK) by BCR-ABL oncoprotein.
    Gotoh A; Miyazawa K; Ohyashiki K; Tauchi T; Boswell HS; Broxmeyer HE; Toyama K
    Exp Hematol; 1995 Oct; 23(11):1153-9. PubMed ID: 7556524
    [TBL] [Abstract][Full Text] [Related]  

  • 16. A novel low-molecular weight inhibitor of focal adhesion kinase, TAE226, inhibits glioma growth.
    Shi Q; Hjelmeland AB; Keir ST; Song L; Wickman S; Jackson D; Ohmori O; Bigner DD; Friedman HS; Rich JN
    Mol Carcinog; 2007 Jun; 46(6):488-96. PubMed ID: 17219439
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Tyrosine phosphorylation profiling reveals the signaling network characteristics of Basal breast cancer cells.
    Hochgräfe F; Zhang L; O'Toole SA; Browne BC; Pinese M; Porta Cubas A; Lehrbach GM; Croucher DR; Rickwood D; Boulghourjian A; Shearer R; Nair R; Swarbrick A; Faratian D; Mullen P; Harrison DJ; Biankin AV; Sutherland RL; Raftery MJ; Daly RJ
    Cancer Res; 2010 Nov; 70(22):9391-401. PubMed ID: 20861192
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Expression of therapeutic targets in Ewing sarcoma family tumors.
    Ahmed AA; Sherman AK; Pawel BR
    Hum Pathol; 2012 Jul; 43(7):1077-83. PubMed ID: 22196127
    [TBL] [Abstract][Full Text] [Related]  

  • 19. PKC-regulated myogenesis is associated with increased tyrosine phosphorylation of FAK, Cas, and paxillin, formation of Cas-CRK complex, and JNK activation.
    Goel HL; Dey CS
    Differentiation; 2002 Aug; 70(6):257-71. PubMed ID: 12190987
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Focal adhesion kinase-related proline-rich tyrosine kinase 2 and focal adhesion kinase are co-overexpressed in early-stage and invasive ErbB-2-positive breast cancer and cooperate for breast cancer cell tumorigenesis and invasiveness.
    Behmoaram E; Bijian K; Jie S; Xu Y; Darnel A; Bismar TA; Alaoui-Jamali MA
    Am J Pathol; 2008 Nov; 173(5):1540-50. PubMed ID: 18832579
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.