BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

273 related articles for article (PubMed ID: 23553560)

  • 1. Axitinib in metastatic renal cell carcinoma: results of a pharmacokinetic and pharmacodynamic analysis.
    Rini BI; Garrett M; Poland B; Dutcher JP; Rixe O; Wilding G; Stadler WM; Pithavala YK; Kim S; Tarazi J; Motzer RJ
    J Clin Pharmacol; 2013 May; 53(5):491-504. PubMed ID: 23553560
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Population pharmacokinetic analysis of axitinib in healthy volunteers.
    Garrett M; Poland B; Brennan M; Hee B; Pithavala YK; Amantea MA
    Br J Clin Pharmacol; 2014 Mar; 77(3):480-92. PubMed ID: 23834452
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Population pharmacokinetic-pharmacodynamic modelling of 24-h diastolic ambulatory blood pressure changes mediated by axitinib in patients with metastatic renal cell carcinoma.
    Chen Y; Rini BI; Bair AH; Mugundu GM; Pithavala YK
    Clin Pharmacokinet; 2015 Apr; 54(4):397-407. PubMed ID: 25343945
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Pharmacokinetics of single-agent axitinib across multiple solid tumor types.
    Tortorici MA; Cohen EE; Pithavala YK; Garrett M; Ruiz-Garcia A; Kim S; Fruehauf JP
    Cancer Chemother Pharmacol; 2014 Dec; 74(6):1279-89. PubMed ID: 25336084
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Effect of Renal Impairment on the Pharmacokinetics and Safety of Axitinib.
    Chen Y; Rini BI; Motzer RJ; Dutcher JP; Rixe O; Wilding G; Stadler WM; Tarazi J; Garrett M; Pithavala YK
    Target Oncol; 2016 Apr; 11(2):229-34. PubMed ID: 26400730
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Axitinib dose titration: analyses of exposure, blood pressure and clinical response from a randomized phase II study in metastatic renal cell carcinoma.
    Rini BI; Melichar B; Fishman MN; Oya M; Pithavala YK; Chen Y; Bair AH; Grünwald V
    Ann Oncol; 2015 Jul; 26(7):1372-7. PubMed ID: 25701454
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Lack of effect of smoking status on axitinib pharmacokinetics in patients with non-small-cell lung cancer.
    Garrett M; Taylor T; Mould DR; Amantea MA; Chen Y; Ingrosso A; Pithavala YK
    Cancer Chemother Pharmacol; 2016 Dec; 78(6):1131-1141. PubMed ID: 27783139
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Hemodialysis does not impact axitinib exposure: clinical case of a patient with metastatic renal cell carcinoma.
    Thiery-Vuillemin A; Orillard E; Mouillet G; Calcagno F; Devillard N; Bouchet S; Royer B
    Cancer Chemother Pharmacol; 2017 Jun; 79(6):1273-1276. PubMed ID: 28451830
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Clinical pharmacology of axitinib.
    Chen Y; Tortorici MA; Garrett M; Hee B; Klamerus KJ; Pithavala YK
    Clin Pharmacokinet; 2013 Sep; 52(9):713-25. PubMed ID: 23677771
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Contribution of UGT1A1 genetic polymorphisms related to axitinib pharmacokinetics to safety and efficacy in patients with renal cell carcinoma.
    Igarashi R; Inoue T; Fujiyama N; Tsuchiya N; Numakura K; Kagaya H; Saito M; Narita S; Satoh S; Niioka T; Miura M; Habuchi T
    Med Oncol; 2018 Mar; 35(4):51. PubMed ID: 29524031
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Axitinib in the treatment of renal cell carcinoma: design, development, and place in therapy.
    Bellesoeur A; Carton E; Alexandre J; Goldwasser F; Huillard O
    Drug Des Devel Ther; 2017; 11():2801-2811. PubMed ID: 29033542
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Comparative effectiveness of axitinib versus sorafenib in advanced renal cell carcinoma (AXIS): a randomised phase 3 trial.
    Rini BI; Escudier B; Tomczak P; Kaprin A; Szczylik C; Hutson TE; Michaelson MD; Gorbunova VA; Gore ME; Rusakov IG; Negrier S; Ou YC; Castellano D; Lim HY; Uemura H; Tarazi J; Cella D; Chen C; Rosbrook B; Kim S; Motzer RJ
    Lancet; 2011 Dec; 378(9807):1931-9. PubMed ID: 22056247
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Key predictive factors of axitinib (AG-013736)-induced proteinuria and efficacy: a phase II study in Japanese patients with cytokine-refractory metastatic renal cell Carcinoma.
    Tomita Y; Uemura H; Fujimoto H; Kanayama HO; Shinohara N; Nakazawa H; Imai K; Umeyama Y; Ozono S; Naito S; Akaza H;
    Eur J Cancer; 2011 Nov; 47(17):2592-602. PubMed ID: 21889330
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Axitinib, a new therapeutic option in renal cell carcinoma.
    Kessler ER; Bowles DW; Flaig TW; Lam ET; Jimeno A
    Drugs Today (Barc); 2012 Oct; 48(10):633-44. PubMed ID: 23110259
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Axitinib for the management of metastatic renal cell carcinoma.
    Escudier B; Gore M
    Drugs R D; 2011; 11(2):113-26. PubMed ID: 21679004
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Overall survival of first-line axitinib in metastatic renal cell carcinoma: Japanese subgroup analysis from phase II study.
    Oya M; Tomita Y; Fukasawa S; Shinohara N; Habuchi T; Rini BI; Fujii Y; Kamei Y; Umeyama Y; Bair AH; Uemura H
    Cancer Sci; 2017 Jun; 108(6):1231-1239. PubMed ID: 28267243
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Axitinib pharmacologic therapeutic monitoring reveals severe under-exposure despite titration in patients with metastatic renal cell carcinoma.
    Beinse G; Hulin A; Rousseau B
    Invest New Drugs; 2019 Dec; 37(6):1289-1291. PubMed ID: 30806848
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Axitinib versus sorafenib as second-line treatment for advanced renal cell carcinoma: overall survival analysis and updated results from a randomised phase 3 trial.
    Motzer RJ; Escudier B; Tomczak P; Hutson TE; Michaelson MD; Negrier S; Oudard S; Gore ME; Tarazi J; Hariharan S; Chen C; Rosbrook B; Kim S; Rini BI
    Lancet Oncol; 2013 May; 14(6):552-62. PubMed ID: 23598172
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Real-World Axitinib Use in the United States: A Retrospective Study Using Linked Datasets.
    MacLean E; Cisar L; Mehle K; Eremina D; Quigley JM
    J Manag Care Spec Pharm; 2016 Jun; 22(6):723-732u. PubMed ID: 27231799
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Pharmacokinetics, metabolism, and excretion of [14C]axitinib, a vascular endothelial growth factor receptor tyrosine kinase inhibitor, in humans.
    Smith BJ; Pithavala Y; Bu HZ; Kang P; Hee B; Deese AJ; Pool WF; Klamerus KJ; Wu EY; Dalvie DK
    Drug Metab Dispos; 2014 May; 42(5):918-31. PubMed ID: 24608633
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 14.