BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

184 related articles for article (PubMed ID: 23565147)

  • 1. Identification, design and bio-evaluation of novel Hsp90 inhibitors by ligand-based virtual screening.
    Jia J; Xu X; Liu F; Guo X; Zhang M; Lu M; Xu L; Wei J; Zhu J; Zhang S; Zhang S; Sun H; You Q
    PLoS One; 2013; 8(4):e59315. PubMed ID: 23565147
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Structure based design of heat shock protein 90 inhibitors acting as anticancer agents.
    Doddareddy MR; Thorat DA; Seo SH; Hong TJ; Cho YS; Hahn JS; Pae AN
    Bioorg Med Chem; 2011 Mar; 19(5):1714-20. PubMed ID: 21306907
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Pharmacophore-based virtual screening and docking studies on Hsp90 inhibitors.
    Saxena S; Chaudhaery SS; Varshney K; Saxena AK
    SAR QSAR Environ Res; 2010 Jul; 21(5-6):445-62. PubMed ID: 20818581
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Identification of New Hsp90 Inhibitors: Structure Based Virtual Screening, Molecular Dynamic Simulation, Synthesis and Biological Evaluation.
    Abbasi M; Amanlou M; Aghaei M; Hassanzadeh F; Sadeghi-Aliabadi H
    Anticancer Agents Med Chem; 2021; 21(18):2583-2591. PubMed ID: 33563187
    [TBL] [Abstract][Full Text] [Related]  

  • 5. 3D QSAR pharmacophore based virtual screening and molecular docking for identification of potential HSP90 inhibitors.
    Sakkiah S; Thangapandian S; John S; Kwon YJ; Lee KW
    Eur J Med Chem; 2010 Jun; 45(6):2132-40. PubMed ID: 20206418
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Discovery of Novel Hsp90 C-Terminal Inhibitors Using 3D-Pharmacophores Derived from Molecular Dynamics Simulations.
    Tomašič T; Durcik M; Keegan BM; Skledar DG; Zajec Ž; Blagg BSJ; Bryant SD
    Int J Mol Sci; 2020 Sep; 21(18):. PubMed ID: 32962253
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Structure-based virtual screening and optimization of modulators targeting Hsp90-Cdc37 interaction.
    Wang L; Li L; Zhou ZH; Jiang ZY; You QD; Xu XL
    Eur J Med Chem; 2017 Aug; 136():63-73. PubMed ID: 28482218
    [TBL] [Abstract][Full Text] [Related]  

  • 8. New heat shock protein (Hsp90) inhibitors, designed by pharmacophore modeling and virtual screening: synthesis, biological evaluation and molecular dynamics studies.
    Abbasi M; Amanlou M; Aghaei M; Bakherad M; Doosti R; Sadeghi-Aliabadi H
    J Biomol Struct Dyn; 2020 Aug; 38(12):3462-3473. PubMed ID: 31452440
    [TBL] [Abstract][Full Text] [Related]  

  • 9. A novel class of Hsp90 inhibitors isolated by structure-based virtual screening.
    Park H; Kim YJ; Hahn JS
    Bioorg Med Chem Lett; 2007 Nov; 17(22):6345-9. PubMed ID: 17869098
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Quinazoline Based HSP90 Inhibitors: Synthesis, Modeling Study and ADME Calculations Towards Breast Cancer Targeting.
    El-Shafey HW; Gomaa RM; El-Messery SM; Goda FE
    Bioorg Med Chem Lett; 2020 Aug; 30(15):127281. PubMed ID: 32527460
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Identification and optimization of novel Hsp90 inhibitors with tetrahydropyrido[4,3-d]pyrimidines core through shape-based screening.
    Sun HP; Jia JM; Jiang F; Xu XL; Liu F; Guo XK; Cherfaoui B; Huang HZ; Pan Y; You QD
    Eur J Med Chem; 2014 May; 79():399-412. PubMed ID: 24763261
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Hsp90 inhibitors, part 2: combining ligand-based and structure-based approaches for virtual screening application.
    Caroli A; Ballante F; Wickersham RB; Corelli F; Ragno R
    J Chem Inf Model; 2014 Mar; 54(3):970-7. PubMed ID: 24555544
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Could the FDA-approved anti-HIV PR inhibitors be promising anticancer agents? An answer from enhanced docking approach and molecular dynamics analyses.
    Arodola OA; Soliman ME
    Drug Des Devel Ther; 2015; 9():6055-65. PubMed ID: 26622167
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Lead generation of heat shock protein 90 inhibitors by a combination of fragment-based approach, virtual screening, and structure-based drug design.
    Miura T; Fukami TA; Hasegawa K; Ono N; Suda A; Shindo H; Yoon DO; Kim SJ; Na YJ; Aoki Y; Shimma N; Tsukuda T; Shiratori Y
    Bioorg Med Chem Lett; 2011 Oct; 21(19):5778-83. PubMed ID: 21875802
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Prediction of new Hsp90 inhibitors based on 3,4-isoxazolediamide scaffold using QSAR study, molecular docking and molecular dynamic simulation.
    Abbasi M; Sadeghi-Aliabadi H; Amanlou M
    Daru; 2017 Jun; 25(1):17. PubMed ID: 28666484
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Identification of new Hsp90 inhibitors by structure-based virtual screening.
    Hong TJ; Park H; Kim YJ; Jeong JH; Hahn JS
    Bioorg Med Chem Lett; 2009 Aug; 19(16):4839-42. PubMed ID: 19560353
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Discovery of potent heat shock protein 90 (Hsp90) inhibitors: structure-based virtual screening, molecular dynamics simulation, and biological evaluation.
    Xu Y; Zou Y; Zhou S; Niu MM; Zhang Y; Li J; Xu Z; Yang L
    J Enzyme Inhib Med Chem; 2023 Dec; 38(1):2220558. PubMed ID: 37357755
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Combined pharmacophore and structure-guided studies to identify diverse HSP90 inhibitors.
    Sanam R; Tajne S; Gundla R; Vadivelan S; Machiraju PK; Dayam R; Narasu L; Jagarlapudi S; Neamati N
    J Mol Graph Model; 2010 Feb; 28(6):472-7. PubMed ID: 20005756
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Fragment-based hit discovery and structure-based optimization of aminotriazoloquinazolines as novel Hsp90 inhibitors.
    Casale E; Amboldi N; Brasca MG; Caronni D; Colombo N; Dalvit C; Felder ER; Fogliatto G; Galvani A; Isacchi A; Polucci P; Riceputi L; Sola F; Visco C; Zuccotto F; Casuscelli F
    Bioorg Med Chem; 2014 Aug; 22(15):4135-50. PubMed ID: 24980703
    [TBL] [Abstract][Full Text] [Related]  

  • 20. QSAR Studies to Predict Activity of HSP90 Inhibitors.
    Patil VM; Masand N; Gupta SP; Blagg BSJ
    Curr Top Med Chem; 2021; 21(25):2272-2291. PubMed ID: 34635040
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.