BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

129 related articles for article (PubMed ID: 23566269)

  • 21. SAR studies of pyridazinone derivatives as novel glucan synthase inhibitors.
    Zhou G; Ting PC; Aslanian R; Cao J; Kim DW; Kuang R; Lee JF; Schwerdt J; Wu H; Herr RJ; Zych AJ; Yang J; Lam S; Wainhaus S; Black TA; McNicholas PM; Xu Y; Walker SS
    Bioorg Med Chem Lett; 2011 May; 21(10):2890-3. PubMed ID: 21489787
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Structural, kinetic, and pharmacodynamic mechanisms of D-amino acid oxidase inhibition by small molecules.
    Hopkins SC; Heffernan ML; Saraswat LD; Bowen CA; Melnick L; Hardy LW; Orsini MA; Allen MS; Koch P; Spear KL; Foglesong RJ; Soukri M; Chytil M; Fang QK; Jones SW; Varney MA; Panatier A; Oliet SH; Pollegioni L; Piubelli L; Molla G; Nardini M; Large TH
    J Med Chem; 2013 May; 56(9):3710-24. PubMed ID: 23631755
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Assessment of the Target Engagement and D-Serine Biomarker Profiles of the D-Amino Acid Oxidase Inhibitors Sodium Benzoate and PGM030756.
    Howley E; Bestwick M; Fradley R; Harrison H; Leveridge M; Okada K; Fieldhouse C; Farnaby W; Canning H; Sykes AP; Merchant K; Hazel K; Kerr C; Kinsella N; Walsh L; Livermore DG; Hoffman I; Ellery J; Mitchell P; Patel T; Carlton M; Barnes M; Miller DJ
    Neurochem Res; 2017 Nov; 42(11):3279-3288. PubMed ID: 28780732
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Co-administration of a D-amino acid oxidase inhibitor potentiates the efficacy of D-serine in attenuating prepulse inhibition deficits after administration of dizocilpine.
    Hashimoto K; Fujita Y; Horio M; Kunitachi S; Iyo M; Ferraris D; Tsukamoto T
    Biol Psychiatry; 2009 Jun; 65(12):1103-6. PubMed ID: 19217074
    [TBL] [Abstract][Full Text] [Related]  

  • 25. The discovery of fused pyrrole carboxylic acids as novel, potent D-amino acid oxidase (DAO) inhibitors.
    Sparey T; Abeywickrema P; Almond S; Brandon N; Byrne N; Campbell A; Hutson PH; Jacobson M; Jones B; Munshi S; Pascarella D; Pike A; Prasad GS; Sachs N; Sakatis M; Sardana V; Venkatraman S; Young MB
    Bioorg Med Chem Lett; 2008 Jun; 18(11):3386-91. PubMed ID: 18455394
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Potential role for astroglial D-amino acid oxidase in extracellular D-serine metabolism and cytotoxicity.
    Park HK; Shishido Y; Ichise-Shishido S; Kawazoe T; Ono K; Iwana S; Tomita Y; Yorita K; Sakai T; Fukui K
    J Biochem; 2006 Feb; 139(2):295-304. PubMed ID: 16452318
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Discovery of d-amino acid oxidase inhibitors based on virtual screening against the lid-open enzyme conformation.
    Szilágyi B; Skok Ž; Rácz A; Frlan R; Ferenczy GG; Ilaš J; Keserű GM
    Bioorg Med Chem Lett; 2018 Jun; 28(10):1693-1698. PubMed ID: 29699925
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Identification of novel D-amino acid oxidase inhibitors by in silico screening and their functional characterization in vitro.
    Katane M; Osaka N; Matsuda S; Maeda K; Kawata T; Saitoh Y; Sekine M; Furuchi T; Doi I; Hirono S; Homma H
    J Med Chem; 2013 Mar; 56(5):1894-907. PubMed ID: 23391306
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Phenyl substituted 4-hydroxypyridazin-3(2H)-ones and 5-hydroxypyrimidin-4(3H)-ones: inhibitors of influenza A endonuclease.
    Sagong HY; Bauman JD; Patel D; Das K; Arnold E; LaVoie EJ
    J Med Chem; 2014 Oct; 57(19):8086-98. PubMed ID: 25225968
    [TBL] [Abstract][Full Text] [Related]  

  • 30. A novel chiral ligand exchange capillary electrophoresis system with amino acid ionic liquid as ligand and its application in screening D-amino-acid oxidase inhibitors.
    Mu X; Qi L; Shen Y; Zhang H; Qiao J; Ma H
    Analyst; 2012 Sep; 137(18):4235-40. PubMed ID: 22858807
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Construction of a D-amino acid oxidase reactor based on magnetic nanoparticles modified by a reactive polymer and its application in screening enzyme inhibitors.
    Mu X; Qiao J; Qi L; Liu Y; Ma H
    ACS Appl Mater Interfaces; 2014 Aug; 6(15):12979-87. PubMed ID: 24980686
    [TBL] [Abstract][Full Text] [Related]  

  • 32. A cell-based ultra-high-throughput screening assay for identifying inhibitors of D-amino acid oxidase.
    Brandish PE; Chiu CS; Schneeweis J; Brandon NJ; Leech CL; Kornienko O; Scolnick EM; Strulovici B; Zheng W
    J Biomol Screen; 2006 Aug; 11(5):481-7. PubMed ID: 16760370
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Novel 3-arylamino- and 3-cycloalkylamino-5, 6-diphenyl-pyridazines active as ACAT inhibitors.
    Toma L; Giovannoni MP; Vergelli C; Dal Piaz V; Kwon BM; Kim YK; Gelain A; Barlocco D
    Arch Pharm (Weinheim); 2002; 335(11-12):563-6. PubMed ID: 12596221
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Structural basis for potent inhibition of d-amino acid oxidase by thiophene carboxylic acids.
    Kato Y; Hin N; Maita N; Thomas AG; Kurosawa S; Rojas C; Yorita K; Slusher BS; Fukui K; Tsukamoto T
    Eur J Med Chem; 2018 Nov; 159():23-34. PubMed ID: 30265959
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Discovery and analgesic evaluation of 8-chloro-1,4-dihydropyrido[2,3-b]pyrazine-2,3-dione as a novel potent d-amino acid oxidase inhibitor.
    Xie D; Lu J; Xie J; Cui J; Li TF; Wang YC; Chen Y; Gong N; Li XY; Fu L; Wang YX
    Eur J Med Chem; 2016 Jul; 117():19-32. PubMed ID: 27089209
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Design and synthesis of potent pyridazine inhibitors of p38 MAP kinase.
    Tamayo N; Liao L; Goldberg M; Powers D; Tudor YY; Yu V; Wong LM; Henkle B; Middleton S; Syed R; Harvey T; Jang G; Hungate R; Dominguez C
    Bioorg Med Chem Lett; 2005 May; 15(9):2409-13. PubMed ID: 15837335
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Biophysical and physicochemical methods differentiate highly ligand-efficient human D-amino acid oxidase inhibitors.
    Lange JH; Venhorst J; van Dongen MJ; Frankena J; Bassissi F; de Bruin NM; den Besten C; de Beer SB; Oostenbrink C; Markova N; Kruse CG
    Eur J Med Chem; 2011 Oct; 46(10):4808-19. PubMed ID: 21880399
    [TBL] [Abstract][Full Text] [Related]  

  • 38. A series of D-amino acid oxidase inhibitors specifically prevents and reverses formalin-induced tonic pain in rats.
    Gong N; Gao ZY; Wang YC; Li XY; Huang JL; Hashimoto K; Wang YX
    J Pharmacol Exp Ther; 2011 Jan; 336(1):282-93. PubMed ID: 20952482
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Discovery of imidazo[1,2-b]pyridazines as IKKβ inhibitors. Part 2: improvement of potency in vitro and in vivo.
    Shimizu H; Yasumatsu I; Hamada T; Yoneda Y; Yamasaki T; Tanaka S; Toki T; Yokoyama M; Morishita K; Iimura S
    Bioorg Med Chem Lett; 2011 Feb; 21(3):904-8. PubMed ID: 21232950
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Imidazo[1,2-b]pyridazines: a potent and selective class of cyclin-dependent kinase inhibitors.
    Byth KF; Cooper N; Culshaw JD; Heaton DW; Oakes SE; Minshull CA; Norman RA; Pauptit RA; Tucker JA; Breed J; Pannifer A; Rowsell S; Stanway JJ; Valentine AL; Thomas AP
    Bioorg Med Chem Lett; 2004 May; 14(9):2249-52. PubMed ID: 15081018
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 7.