BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

170 related articles for article (PubMed ID: 23566299)

  • 1. Determination of the α-conotoxin Vc1.1 binding site on the α9α10 nicotinic acetylcholine receptor.
    Yu R; Kompella SN; Adams DJ; Craik DJ; Kaas Q
    J Med Chem; 2013 May; 56(9):3557-67. PubMed ID: 23566299
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Interaction of rat α9α10 nicotinic acetylcholine receptor with α-conotoxin RgIA and Vc1.1: Insights from docking, molecular dynamics and binding free energy contributions.
    Li R; Li X; Jiang J; Tian Y; Liu D; Zhangsun D; Fu Y; Wu Y; Luo S
    J Mol Graph Model; 2019 Nov; 92():55-64. PubMed ID: 31330438
    [TBL] [Abstract][Full Text] [Related]  

  • 3. α-Conotoxin Vc1.1 Structure-Activity Relationship at the Human α9α10 Nicotinic Acetylcholine Receptor Investigated by Minimal Side Chain Replacement.
    Chu X; Tae HS; Xu Q; Jiang T; Adams DJ; Yu R
    ACS Chem Neurosci; 2019 Oct; 10(10):4328-4336. PubMed ID: 31411453
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Presence of multiple binding sites on α9α10 nAChR receptors alludes to stoichiometric-dependent action of the α-conotoxin, Vc1.1.
    Indurthi DC; Pera E; Kim HL; Chu C; McLeod MD; McIntosh JM; Absalom NL; Chebib M
    Biochem Pharmacol; 2014 May; 89(1):131-40. PubMed ID: 24548457
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Are alpha9alpha10 nicotinic acetylcholine receptors a pain target for alpha-conotoxins?
    Nevin ST; Clark RJ; Klimis H; Christie MJ; Craik DJ; Adams DJ
    Mol Pharmacol; 2007 Dec; 72(6):1406-10. PubMed ID: 17804600
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Conotoxin Interactions with α9α10-nAChRs: Is the α9α10-Nicotinic Acetylcholine Receptor an Important Therapeutic Target for Pain Management?
    Mohammadi SA; Christie MJ
    Toxins (Basel); 2015 Sep; 7(10):3916-32. PubMed ID: 26426047
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Scanning mutagenesis of alpha-conotoxin Vc1.1 reveals residues crucial for activity at the alpha9alpha10 nicotinic acetylcholine receptor.
    Halai R; Clark RJ; Nevin ST; Jensen JE; Adams DJ; Craik DJ
    J Biol Chem; 2009 Jul; 284(30):20275-84. PubMed ID: 19447885
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Molecular Determinants Conferring the Stoichiometric-Dependent Activity of α-Conotoxins at the Human α9α10 Nicotinic Acetylcholine Receptor Subtype.
    Yu R; Tae HS; Tabassum N; Shi J; Jiang T; Adams DJ
    J Med Chem; 2018 May; 61(10):4628-4634. PubMed ID: 29733583
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Alpha-RgIA, a novel conotoxin that blocks the alpha9alpha10 nAChR: structure and identification of key receptor-binding residues.
    Ellison M; Feng ZP; Park AJ; Zhang X; Olivera BM; McIntosh JM; Norton RS
    J Mol Biol; 2008 Apr; 377(4):1216-27. PubMed ID: 18295795
    [TBL] [Abstract][Full Text] [Related]  

  • 10. αO-Conotoxin GeXIVA disulfide bond isomers exhibit differential sensitivity for various nicotinic acetylcholine receptors but retain potency and selectivity for the human α9α10 subtype.
    Zhangsun D; Zhu X; Kaas Q; Wu Y; Craik DJ; McIntosh JM; Luo S
    Neuropharmacology; 2017 Dec; 127():243-252. PubMed ID: 28416445
    [TBL] [Abstract][Full Text] [Related]  

  • 11. αS-conotoxin GVIIIB potently and selectively blocks α9α10 nicotinic acetylcholine receptors.
    Christensen SB; Bandyopadhyay PK; Olivera BM; McIntosh JM
    Biochem Pharmacol; 2015 Aug; 96(4):349-56. PubMed ID: 26074268
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Structure and activity of alpha-conotoxin PeIA at nicotinic acetylcholine receptor subtypes and GABA(B) receptor-coupled N-type calcium channels.
    Daly NL; Callaghan B; Clark RJ; Nevin ST; Adams DJ; Craik DJ
    J Biol Chem; 2011 Mar; 286(12):10233-7. PubMed ID: 21252227
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Molecular interaction of α-conotoxin RgIA with the rat α9α10 nicotinic acetylcholine receptor.
    Azam L; Papakyriakou A; Zouridakis M; Giastas P; Tzartos SJ; McIntosh JM
    Mol Pharmacol; 2015 May; 87(5):855-64. PubMed ID: 25740413
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Dicarba α-conotoxin Vc1.1 analogues with differential selectivity for nicotinic acetylcholine and GABAB receptors.
    van Lierop BJ; Robinson SD; Kompella SN; Belgi A; McArthur JR; Hung A; MacRaild CA; Adams DJ; Norton RS; Robinson AJ
    ACS Chem Biol; 2013 Aug; 8(8):1815-21. PubMed ID: 23768016
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Dimerization of α-Conotoxins as a Strategy to Enhance the Inhibition of the Human α7 and α9α10 Nicotinic Acetylcholine Receptors.
    Liang J; Tae HS; Xu X; Jiang T; Adams DJ; Yu R
    J Med Chem; 2020 Mar; 63(6):2974-2985. PubMed ID: 32101438
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Cloning, synthesis, and characterization of αO-conotoxin GeXIVA, a potent α9α10 nicotinic acetylcholine receptor antagonist.
    Luo S; Zhangsun D; Harvey PJ; Kaas Q; Wu Y; Zhu X; Hu Y; Li X; Tsetlin VI; Christensen S; Romero HK; McIntyre M; Dowell C; Baxter JC; Elmslie KS; Craik DJ; McIntosh JM
    Proc Natl Acad Sci U S A; 2015 Jul; 112(30):E4026-35. PubMed ID: 26170295
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Medicinal chemistry, pharmacology, and therapeutic potential of α-conotoxins antagonizing the α9α10 nicotinic acetylcholine receptor.
    Li X; Tae HS; Chu Y; Jiang T; Adams DJ; Yu R
    Pharmacol Ther; 2021 Jun; 222():107792. PubMed ID: 33309557
    [TBL] [Abstract][Full Text] [Related]  

  • 18. A novel mechanism of inhibition of high-voltage activated calcium channels by α-conotoxins contributes to relief of nerve injury-induced neuropathic pain.
    Klimis H; Adams DJ; Callaghan B; Nevin S; Alewood PF; Vaughan CW; Mozar CA; Christie MJ
    Pain; 2011 Feb; 152(2):259-266. PubMed ID: 20889259
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Identification of a Novel O-Conotoxin Reveals an Unusual and Potent Inhibitor of the Human α9α10 Nicotinic Acetylcholine Receptor.
    Jiang S; Tae HS; Xu S; Shao X; Adams DJ; Wang C
    Mar Drugs; 2017 Jun; 15(6):. PubMed ID: 28598389
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Structure-Activity Studies Reveal the Molecular Basis for GABA
    Sadeghi M; Carstens BB; Callaghan BP; Daniel JT; Tae HS; O'Donnell T; Castro J; Brierley SM; Adams DJ; Craik DJ; Clark RJ
    ACS Chem Biol; 2018 Jun; 13(6):1577-1587. PubMed ID: 29746088
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.