BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

243 related articles for article (PubMed ID: 23570232)

  • 1. Adenine-DNA adducts derived from the highly tumorigenic Dibenzo[a,l]pyrene are resistant to nucleotide excision repair while guanine adducts are not.
    Kropachev K; Kolbanovskiy M; Liu Z; Cai Y; Zhang L; Schwaid AG; Kolbanovskiy A; Ding S; Amin S; Broyde S; Geacintov NE
    Chem Res Toxicol; 2013 May; 26(5):783-93. PubMed ID: 23570232
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Nuclear magnetic resonance studies of an N2-guanine adduct derived from the tumorigen dibenzo[a,l]pyrene in DNA: impact of adduct stereochemistry, size, and local DNA sequence on solution conformations.
    Rodríguez FA; Liu Z; Lin CH; Ding S; Cai Y; Kolbanovskiy A; Kolbanovskiy M; Amin S; Broyde S; Geacintov NE
    Biochemistry; 2014 Mar; 53(11):1827-41. PubMed ID: 24617538
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Synthesis and characterization of site-specific and stereoisomeric fjord dibenzo[a,l]pyrene diol epoxide-N(6)-adenine adducts: unusual thermal stabilization of modified DNA duplexes.
    Ruan Q; Kolbanovskiy A; Zhuang P; Chen J; Krzeminski J; Amin S; Geacintov NE
    Chem Res Toxicol; 2002 Feb; 15(2):249-61. PubMed ID: 11849052
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Nuclear magnetic resonance solution structure of an N(2)-guanine DNA adduct derived from the potent tumorigen dibenzo[a,l]pyrene: intercalation from the minor groove with ruptured Watson-Crick base pairing.
    Tang Y; Liu Z; Ding S; Lin CH; Cai Y; Rodriguez FA; Sayer JM; Jerina DM; Amin S; Broyde S; Geacintov NE
    Biochemistry; 2012 Dec; 51(48):9751-62. PubMed ID: 23121427
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Adenine-DNA adduct derived from the nitroreduction of 6-nitrochrysene is more resistant to nucleotide excision repair than guanine-DNA adducts.
    Krzeminski J; Kropachev K; Reeves D; Kolbanovskiy A; Kolbanovskiy M; Chen KM; Sharma AK; Geacintov N; Amin S; El-Bayoumy K
    Chem Res Toxicol; 2013 Nov; 26(11):1746-54. PubMed ID: 24112095
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Intercalative conformations of the 14R (+)- and 14S (-)-trans-anti-DB[a,l]P-N⁶-dA adducts: molecular modeling and MD simulations.
    Cai Y; Ding S; Geacintov NE; Broyde S
    Chem Res Toxicol; 2011 Apr; 24(4):522-31. PubMed ID: 21361377
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Differential removal of DNA adducts derived from anti-diol epoxides of dibenzo[a,l]pyrene and benzo[a]pyrene in human cells.
    Dreij K; Seidel A; Jernström B
    Chem Res Toxicol; 2005 Apr; 18(4):655-64. PubMed ID: 15833025
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Thermodynamic and structural factors in the removal of bulky DNA adducts by the nucleotide excision repair machinery.
    Geacintov NE; Broyde S; Buterin T; Naegeli H; Wu M; Yan S; Patel DJ
    Biopolymers; 2002 Nov; 65(3):202-10. PubMed ID: 12228925
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Resistance to Nucleotide Excision Repair of Bulky Guanine Adducts Opposite Abasic Sites in DNA Duplexes and Relationships between Structure and Function.
    Liu Z; Ding S; Kropachev K; Jia L; Amin S; Broyde S; Geacintov NE
    PLoS One; 2015; 10(9):e0137124. PubMed ID: 26340000
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Solution structure of the (+)-cis-anti-benzo[a]pyrene-dA ([BP]dA) adduct opposite dT in a DNA duplex.
    Mao B; Gu Z; Gorin A; Chen J; Hingerty BE; Amin S; Broyde S; Geacintov NE; Patel DJ
    Biochemistry; 1999 Aug; 38(33):10831-42. PubMed ID: 10451380
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Nucleotide excision repair efficiencies of bulky carcinogen-DNA adducts are governed by a balance between stabilizing and destabilizing interactions.
    Cai Y; Geacintov NE; Broyde S
    Biochemistry; 2012 Feb; 51(7):1486-99. PubMed ID: 22242833
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Free energy profiles of base flipping in intercalative polycyclic aromatic hydrocarbon-damaged DNA duplexes: energetic and structural relationships to nucleotide excision repair susceptibility.
    Cai Y; Zheng H; Ding S; Kropachev K; Schwaid AG; Tang Y; Mu H; Wang S; Geacintov NE; Zhang Y; Broyde S
    Chem Res Toxicol; 2013 Jul; 26(7):1115-25. PubMed ID: 23758590
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Unrepaired fjord region polycyclic aromatic hydrocarbon-DNA adducts in ras codon 61 mutational hot spots.
    Buterin T; Hess MT; Luneva N; Geacintov NE; Amin S; Kroth H; Seidel A; Naegeli H
    Cancer Res; 2000 Apr; 60(7):1849-56. PubMed ID: 10766171
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Resistance of bulky DNA lesions to nucleotide excision repair can result from extensive aromatic lesion-base stacking interactions.
    Reeves DA; Mu H; Kropachev K; Cai Y; Ding S; Kolbanovskiy A; Kolbanovskiy M; Chen Y; Krzeminski J; Amin S; Patel DJ; Broyde S; Geacintov NE
    Nucleic Acids Res; 2011 Nov; 39(20):8752-64. PubMed ID: 21764772
    [TBL] [Abstract][Full Text] [Related]  

  • 15. DNA adducts from a tumorigenic metabolite of benzo[a]pyrene block human RNA polymerase II elongation in a sequence- and stereochemistry-dependent manner.
    Perlow RA; Kolbanovskii A; Hingerty BE; Geacintov NE; Broyde S; Scicchitano DA
    J Mol Biol; 2002 Aug; 321(1):29-47. PubMed ID: 12139931
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Relating repair susceptibility of carcinogen-damaged DNA with structural distortion and thermodynamic stability.
    Wu M; Yan S; Patel DJ; Geacintov NE; Broyde S
    Nucleic Acids Res; 2002 Aug; 30(15):3422-32. PubMed ID: 12140327
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Molecular topology of polycyclic aromatic carcinogens determines DNA adduct conformation: a link to tumorigenic activity.
    Lin CH; Huang X; Kolbanovskii A; Hingerty BE; Amin S; Broyde S; Geacintov NE; Patel DJ
    J Mol Biol; 2001 Mar; 306(5):1059-80. PubMed ID: 11237618
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Metabolic activation of racemic and enantiomeric trans-8, 9-dihydroxy-8,9-dihydrodibenzo[a,l]pyrene (dibenzo[def,p]chrysene) to dibenzo[a,l]pyrene-bis-dihydrodiols by induced rat liver microsomes and a recombinant human P450 1A1 system: the role of the K-region-derived metabolic intermediates in the formation of dibenzo[a,l]pyrene-DNA adducts.
    Nesnow S; Davis C; Padgett W; George M; Lambert G; Meyers F; Allison J; Adams L; King LC
    Chem Res Toxicol; 1998 Dec; 11(12):1596-607. PubMed ID: 9860506
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Nucleotide Excision Repair and Impact of Site-Specific 5',8-Cyclopurine and Bulky DNA Lesions on the Physical Properties of Nucleosomes.
    Shafirovich V; Kolbanovskiy M; Kropachev K; Liu Z; Cai Y; Terzidis MA; Masi A; Chatgilialoglu C; Amin S; Dadali A; Broyde S; Geacintov NE
    Biochemistry; 2019 Feb; 58(6):561-574. PubMed ID: 30570250
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Formation and differential repair of covalent DNA adducts generated by treatment of human cells with (+/-)-anti-dibenzo[a,l]pyrene-11,12-diol-13,14-epoxide.
    Spencer WA; Singh J; Orren DK
    Chem Res Toxicol; 2009 Jan; 22(1):81-9. PubMed ID: 19053321
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.