These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

269 related articles for article (PubMed ID: 23573918)

  • 1. Targeting ApoE4/ApoE receptor LRP1 in Alzheimer's disease.
    Martiskainen H; Haapasalo A; Kurkinen KM; Pihlajamäki J; Soininen H; Hiltunen M
    Expert Opin Ther Targets; 2013 Jul; 17(7):781-94. PubMed ID: 23573918
    [TBL] [Abstract][Full Text] [Related]  

  • 2. APOE4-mediated amyloid-β pathology depends on its neuronal receptor LRP1.
    Tachibana M; Holm ML; Liu CC; Shinohara M; Aikawa T; Oue H; Yamazaki Y; Martens YA; Murray ME; Sullivan PM; Weyer K; Glerup S; Dickson DW; Bu G; Kanekiyo T
    J Clin Invest; 2019 Mar; 129(3):1272-1277. PubMed ID: 30741718
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Apolipoprotein E increases cell association of amyloid-β 40 through heparan sulfate and LRP1 dependent pathways.
    O'Callaghan P; Noborn F; Sehlin D; Li JP; Lannfelt L; Lindahl U; Zhang X
    Amyloid; 2014 Jun; 21(2):76-87. PubMed ID: 24491019
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Apolipoprotein E/Amyloid-β Complex Accumulates in Alzheimer Disease Cortical Synapses via Apolipoprotein E Receptors and Is Enhanced by APOE4.
    Bilousova T; Melnik M; Miyoshi E; Gonzalez BL; Poon WW; Vinters HV; Miller CA; Corrada MM; Kawas C; Hatami A; Albay R; Glabe C; Gylys KH
    Am J Pathol; 2019 Aug; 189(8):1621-1636. PubMed ID: 31108099
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Inhibition of ADAM10 promotes the clearance of Aβ across the BBB by reducing LRP1 ectodomain shedding.
    Shackleton B; Crawford F; Bachmeier C
    Fluids Barriers CNS; 2016 Aug; 13(1):14. PubMed ID: 27503326
    [TBL] [Abstract][Full Text] [Related]  

  • 6. apoE isoform-specific disruption of amyloid beta peptide clearance from mouse brain.
    Deane R; Sagare A; Hamm K; Parisi M; Lane S; Finn MB; Holtzman DM; Zlokovic BV
    J Clin Invest; 2008 Dec; 118(12):4002-13. PubMed ID: 19033669
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Blood-brain barrier-associated pericytes internalize and clear aggregated amyloid-β42 by LRP1-dependent apolipoprotein E isoform-specific mechanism.
    Ma Q; Zhao Z; Sagare AP; Wu Y; Wang M; Owens NC; Verghese PB; Herz J; Holtzman DM; Zlokovic BV
    Mol Neurodegener; 2018 Oct; 13(1):57. PubMed ID: 30340601
    [TBL] [Abstract][Full Text] [Related]  

  • 8. A multifaceted role for apoE in the clearance of beta-amyloid across the blood-brain barrier.
    Bachmeier C; Paris D; Beaulieu-Abdelahad D; Mouzon B; Mullan M; Crawford F
    Neurodegener Dis; 2013; 11(1):13-21. PubMed ID: 22572854
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Apolipoprotein E, amyloid-beta, and blood-brain barrier permeability in Alzheimer disease.
    Donahue JE; Johanson CE
    J Neuropathol Exp Neurol; 2008 Apr; 67(4):261-70. PubMed ID: 18379441
    [TBL] [Abstract][Full Text] [Related]  

  • 10. High ability of apolipoprotein E4 to stabilize amyloid-β peptide oligomers, the pathological entities responsible for Alzheimer's disease.
    Cerf E; Gustot A; Goormaghtigh E; Ruysschaert JM; Raussens V
    FASEB J; 2011 May; 25(5):1585-95. PubMed ID: 21266538
    [TBL] [Abstract][Full Text] [Related]  

  • 11. LRP1 mediates bidirectional transcytosis of amyloid-β across the blood-brain barrier.
    Pflanzner T; Janko MC; André-Dohmen B; Reuss S; Weggen S; Roebroek AJ; Kuhlmann CR; Pietrzik CU
    Neurobiol Aging; 2011 Dec; 32(12):2323.e1-11. PubMed ID: 20630619
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Endothelial LRP1 - A Potential Target for the Treatment of Alzheimer's Disease : Theme: Drug Discovery, Development and Delivery in Alzheimer's Disease Guest Editor: Davide Brambilla.
    Storck SE; Pietrzik CU
    Pharm Res; 2017 Dec; 34(12):2637-2651. PubMed ID: 28948494
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The pathological cross talk between apolipoprotein E and amyloid-beta peptide in Alzheimer's disease: emerging gene-based therapeutic approaches.
    Iurescia S; Fioretti D; Mangialasche F; Rinaldi M
    J Alzheimers Dis; 2010; 21(1):35-48. PubMed ID: 20182014
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Dr. Jekyll and Mr. Hyde: ApoE explains opposing effects of neuronal LRP1.
    Strickland MR; Holtzman DM
    J Clin Invest; 2019 Mar; 129(3):969-971. PubMed ID: 30741722
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Roles of apolipoprotein E4 (ApoE4) in the pathogenesis of Alzheimer's disease: lessons from ApoE mouse models.
    Huang Y
    Biochem Soc Trans; 2011 Aug; 39(4):924-32. PubMed ID: 21787325
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Intraneuronal amyloid-beta plays a role in mediating the synergistic pathological effects of apoE4 and environmental stimulation.
    Levi O; Dolev I; Belinson H; Michaelson DM
    J Neurochem; 2007 Nov; 103(3):1031-40. PubMed ID: 17666042
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Abeta-independent roles of apolipoprotein E4 in the pathogenesis of Alzheimer's disease.
    Huang Y
    Trends Mol Med; 2010 Jun; 16(6):287-94. PubMed ID: 20537952
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Role of the cannabinoid system in the transit of beta-amyloid across the blood-brain barrier.
    Bachmeier C; Beaulieu-Abdelahad D; Mullan M; Paris D
    Mol Cell Neurosci; 2013 Sep; 56():255-62. PubMed ID: 23831388
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Apolipoprotein E receptor pathways in Alzheimer disease.
    Schmidt V; Carlo AS; Willnow TE
    Wiley Interdiscip Rev Syst Biol Med; 2014; 6(3):255-70. PubMed ID: 24604742
    [TBL] [Abstract][Full Text] [Related]  

  • 20. LRP1 expression in cerebral cortex, choroid plexus and meningeal blood vessels: relationship to cerebral amyloid angiopathy and APOE status.
    Ruzali WA; Kehoe PG; Love S
    Neurosci Lett; 2012 Sep; 525(2):123-8. PubMed ID: 22967844
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 14.