124 related articles for article (PubMed ID: 23580570)
1. Single copies of mutant KRAS and mutant PIK3CA cooperate in immortalized human epithelial cells to induce tumor formation.
Wang GM; Wong HY; Konishi H; Blair BG; Abukhdeir AM; Gustin JP; Rosen DM; Denmeade SR; Rasheed Z; Matsui W; Garay JP; Mohseni M; Higgins MJ; Cidado J; Jelovac D; Croessmann S; Cochran RL; Karnan S; Konishi Y; Ota A; Hosokawa Y; Argani P; Lauring J; Park BH
Cancer Res; 2013 Jun; 73(11):3248-61. PubMed ID: 23580570
[TBL] [Abstract][Full Text] [Related]
2. AKT-independent signaling downstream of oncogenic PIK3CA mutations in human cancer.
Vasudevan KM; Barbie DA; Davies MA; Rabinovsky R; McNear CJ; Kim JJ; Hennessy BT; Tseng H; Pochanard P; Kim SY; Dunn IF; Schinzel AC; Sandy P; Hoersch S; Sheng Q; Gupta PB; Boehm JS; Reiling JH; Silver S; Lu Y; Stemke-Hale K; Dutta B; Joy C; Sahin AA; Gonzalez-Angulo AM; Lluch A; Rameh LE; Jacks T; Root DE; Lander ES; Mills GB; Hahn WC; Sellers WR; Garraway LA
Cancer Cell; 2009 Jul; 16(1):21-32. PubMed ID: 19573809
[TBL] [Abstract][Full Text] [Related]
3. PI3K regulation of RAC1 is required for KRAS-induced pancreatic tumorigenesis in mice.
Wu CY; Carpenter ES; Takeuchi KK; Halbrook CJ; Peverley LV; Bien H; Hall JC; DelGiorno KE; Pal D; Song Y; Shi C; Lin RZ; Crawford HC
Gastroenterology; 2014 Dec; 147(6):1405-16.e7. PubMed ID: 25311989
[TBL] [Abstract][Full Text] [Related]
4. Breast Cancer Heterogeneity Examined by High-Sensitivity Quantification of PIK3CA, KRAS, HRAS, and BRAF Mutations in Normal Breast and Ductal Carcinomas.
Myers MB; Banda M; McKim KL; Wang Y; Powell MJ; Parsons BL
Neoplasia; 2016 Apr; 18(4):253-63. PubMed ID: 27108388
[TBL] [Abstract][Full Text] [Related]
5. Disruption of epithelial architecture caused by loss of PTEN or by oncogenic mutant p110α/PIK3CA but not by HER2 or mutant AKT1.
Berglund FM; Weerasinghe NR; Davidson L; Lim JC; Eickholt BJ; Leslie NR
Oncogene; 2013 Sep; 32(37):4417-26. PubMed ID: 23085752
[TBL] [Abstract][Full Text] [Related]
6. Phosphatidylinositol 3-kinase mutations identified in human cancer are oncogenic.
Kang S; Bader AG; Vogt PK
Proc Natl Acad Sci U S A; 2005 Jan; 102(3):802-7. PubMed ID: 15647370
[TBL] [Abstract][Full Text] [Related]
7. Knock in of the AKT1 E17K mutation in human breast epithelial cells does not recapitulate oncogenic PIK3CA mutations.
Lauring J; Cosgrove DP; Fontana S; Gustin JP; Konishi H; Abukhdeir AM; Garay JP; Mohseni M; Wang GM; Higgins MJ; Gorkin D; Reis M; Vogelstein B; Polyak K; Cowherd M; Buckhaults PJ; Park BH
Oncogene; 2010 Apr; 29(16):2337-45. PubMed ID: 20101210
[TBL] [Abstract][Full Text] [Related]
8. HER3 and downstream pathways are involved in colonization of brain metastases from breast cancer.
Da Silva L; Simpson PT; Smart CE; Cocciardi S; Waddell N; Lane A; Morrison BJ; Vargas AC; Healey S; Beesley J; Pakkiri P; Parry S; Kurniawan N; Reid L; Keith P; Faria P; Pereira E; Skalova A; Bilous M; Balleine RL; Do H; Dobrovic A; Fox S; Franco M; Reynolds B; Khanna KK; Cummings M; Chenevix-Trench G; Lakhani SR
Breast Cancer Res; 2010; 12(4):R46. PubMed ID: 20604919
[TBL] [Abstract][Full Text] [Related]
9. RSK is a principal effector of the RAS-ERK pathway for eliciting a coordinate promotile/invasive gene program and phenotype in epithelial cells.
Doehn U; Hauge C; Frank SR; Jensen CJ; Duda K; Nielsen JV; Cohen MS; Johansen JV; Winther BR; Lund LR; Winther O; Taunton J; Hansen SH; Frödin M
Mol Cell; 2009 Aug; 35(4):511-22. PubMed ID: 19716794
[TBL] [Abstract][Full Text] [Related]
10. GeLC-MRM quantitation of mutant KRAS oncoprotein in complex biological samples.
Halvey PJ; Ferrone CR; Liebler DC
J Proteome Res; 2012 Jul; 11(7):3908-13. PubMed ID: 22671702
[TBL] [Abstract][Full Text] [Related]
11. Mutant KRAS Conversion of Conventional T Cells into Regulatory T Cells.
Zdanov S; Mandapathil M; Abu Eid R; Adamson-Fadeyi S; Wilson W; Qian J; Carnie A; Tarasova N; Mkrtichyan M; Berzofsky JA; Whiteside TL; Khleif SN
Cancer Immunol Res; 2016 Apr; 4(4):354-65. PubMed ID: 26880715
[TBL] [Abstract][Full Text] [Related]
12. Oncogenic PIK3CA induces centrosome amplification and tolerance to genome doubling.
Berenjeno IM; Piñeiro R; Castillo SD; Pearce W; McGranahan N; Dewhurst SM; Meniel V; Birkbak NJ; Lau E; Sansregret L; Morelli D; Kanu N; Srinivas S; Graupera M; Parker VER; Montgomery KG; Moniz LS; Scudamore CL; Phillips WA; Semple RK; Clarke A; Swanton C; Vanhaesebroeck B
Nat Commun; 2017 Nov; 8(1):1773. PubMed ID: 29170395
[TBL] [Abstract][Full Text] [Related]
13. R-Ras promotes metastasis of cervical cancer epithelial cells.
Mora N; Rosales R; Rosales C
Cancer Immunol Immunother; 2007 Apr; 56(4):535-44. PubMed ID: 16862428
[TBL] [Abstract][Full Text] [Related]
14. Mechanoactivation of NOX2-generated ROS elicits persistent TRPM8 Ca
Pratt SJP; Lee RM; Chang KT; Hernández-Ochoa EO; Annis DA; Ory EC; Thompson KN; Bailey PC; Mathias TJ; Ju JA; Vitolo MI; Schneider MF; Stains JP; Ward CW; Martin SS
Proc Natl Acad Sci U S A; 2020 Oct; 117(42):26008-26019. PubMed ID: 33020304
[TBL] [Abstract][Full Text] [Related]
15. Arachidonic acid released by PIK3CA mutant tumor cells triggers malignant transformation of colonic epithelium by inducing chromatin remodeling.
He B; Bie Q; Zhao R; Yan Y; Dong G; Zhang B; Wang S; Xu W; Tian D; Hao Y; Zhang Y; Zhao M; Xiong H; Zhang B
Cell Rep Med; 2024 May; 5(5):101510. PubMed ID: 38614093
[TBL] [Abstract][Full Text] [Related]
16. Activating the expression of human K-rasG12D stimulates oncogenic transformation in transgenic goat fetal fibroblast cells.
Gong J; Wang Z; Polejaeva I; Salgia R; Kao CM; Chen CT; Chen G; Chen L
PLoS One; 2014; 9(3):e90059. PubMed ID: 24594684
[TBL] [Abstract][Full Text] [Related]
17. Activation of phosphatidylinositol 3-kinase (PI3K) and mitogen-activated protein kinase (MAPK) signaling and the consequent induction of transformation by overexpressed 14-3-3γ protein require specific amino acids within 14-3-3γ N-terminal variable region II.
Radhakrishnan VM; Putnam CW; Martinez JD
J Biol Chem; 2012 Dec; 287(52):43300-11. PubMed ID: 23115241
[TBL] [Abstract][Full Text] [Related]
18. Transcriptional regulation of PIK3CA oncogene by NF-kappaB in ovarian cancer microenvironment.
Yang N; Huang J; Greshock J; Liang S; Barchetti A; Hasegawa K; Kim S; Giannakakis A; Li C; O'Brien-Jenkins A; Katsaros D; Bützow R; Coukos G; Zhang L
PLoS One; 2008 Mar; 3(3):e1758. PubMed ID: 18335034
[TBL] [Abstract][Full Text] [Related]
19. The paradox of cancer genes in non-malignant conditions: implications for precision medicine.
Adashek JJ; Kato S; Lippman SM; Kurzrock R
Genome Med; 2020 Feb; 12(1):16. PubMed ID: 32066498
[TBL] [Abstract][Full Text] [Related]
20. The Atypical Kinase RIOK1 Promotes Tumor Growth and Invasive Behavior.
Weinberg F; Reischmann N; Fauth L; Taromi S; Mastroianni J; Köhler M; Halbach S; Becker AC; Deng N; Schmitz T; Uhl FM; Herbener N; Riedel B; Beier F; Swarbrick A; Lassmann S; Dengjel J; Zeiser R; Brummer T
EBioMedicine; 2017 Jun; 20():79-97. PubMed ID: 28499923
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
