BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

250 related articles for article (PubMed ID: 23580664)

  • 1. The large ectodomains of CD45 and CD148 regulate their segregation from and inhibition of ligated T-cell receptor.
    Cordoba SP; Choudhuri K; Zhang H; Bridge M; Basat AB; Dustin ML; van der Merwe PA
    Blood; 2013 May; 121(21):4295-302. PubMed ID: 23580664
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Regulation of Src family kinases involved in T cell receptor signaling by protein-tyrosine phosphatase CD148.
    Stepanek O; Kalina T; Draber P; Skopcova T; Svojgr K; Angelisova P; Horejsi V; Weiss A; Brdicka T
    J Biol Chem; 2011 Jun; 286(25):22101-12. PubMed ID: 21543337
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Costimulation of IL-2 Production through CD28 Is Dependent on the Size of Its Ligand.
    Lim HS; Cordoba SP; Dushek O; Goyette J; Taylor A; Rudd CE; van der Merwe PA
    J Immunol; 2015 Dec; 195(11):5432-9. PubMed ID: 26500347
    [TBL] [Abstract][Full Text] [Related]  

  • 4. CD45 ectodomain controls interaction with GEMs and Lck activity for optimal TCR signaling.
    Irles C; Symons A; Michel F; Bakker TR; van der Merwe PA; Acuto O
    Nat Immunol; 2003 Feb; 4(2):189-97. PubMed ID: 12496963
    [TBL] [Abstract][Full Text] [Related]  

  • 5. T-cell receptor triggering is critically dependent on the dimensions of its peptide-MHC ligand.
    Choudhuri K; Wiseman D; Brown MH; Gould K; van der Merwe PA
    Nature; 2005 Jul; 436(7050):578-82. PubMed ID: 16049493
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Structurally distinct phosphatases CD45 and CD148 both regulate B cell and macrophage immunoreceptor signaling.
    Zhu JW; Brdicka T; Katsumoto TR; Lin J; Weiss A
    Immunity; 2008 Feb; 28(2):183-96. PubMed ID: 18249142
    [TBL] [Abstract][Full Text] [Related]  

  • 7. High-Affinity Ligands Can Trigger T Cell Receptor Signaling Without CD45 Segregation.
    Al-Aghbar MA; Chu YS; Chen BM; Roffler SR
    Front Immunol; 2018; 9():713. PubMed ID: 29686683
    [TBL] [Abstract][Full Text] [Related]  

  • 8. In vitro reconstitution of T cell receptor-mediated segregation of the CD45 phosphatase.
    Carbone CB; Kern N; Fernandes RA; Hui E; Su X; Garcia KC; Vale RD
    Proc Natl Acad Sci U S A; 2017 Oct; 114(44):E9338-E9345. PubMed ID: 29042512
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Biochemical association of CD45 with the T cell receptor complex: regulation by CD45 isoform and during T cell activation.
    Leitenberg D; Boutin Y; Lu DD; Bottomly K
    Immunity; 1999 Jun; 10(6):701-11. PubMed ID: 10403645
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Initiation of T cell signaling by CD45 segregation at 'close contacts'.
    Chang VT; Fernandes RA; Ganzinger KA; Lee SF; Siebold C; McColl J; Jönsson P; Palayret M; Harlos K; Coles CH; Jones EY; Lui Y; Huang E; Gilbert RJC; Klenerman D; Aricescu AR; Davis SJ
    Nat Immunol; 2016 May; 17(5):574-582. PubMed ID: 26998761
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The extracellular domain of CD45 controls association with the CD4-T cell receptor complex and the response to antigen-specific stimulation.
    Leitenberg D; Novak TJ; Farber D; Smith BR; Bottomly K
    J Exp Med; 1996 Jan; 183(1):249-59. PubMed ID: 8551228
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Negative regulation of human T cell activation by the receptor-type protein tyrosine phosphatase CD148.
    Tangye SG; Wu J; Aversa G; de Vries JE; Lanier LL; Phillips JH
    J Immunol; 1998 Oct; 161(8):3803-7. PubMed ID: 9780142
    [TBL] [Abstract][Full Text] [Related]  

  • 13. CD45-mediated control of TCR tuning in naïve and memory CD8
    Cho JH; Kim HO; Ju YJ; Kye YC; Lee GW; Lee SW; Yun CH; Bottini N; Webster K; Goodnow CC; Surh CD; King C; Sprent J
    Nat Commun; 2016 Nov; 7():13373. PubMed ID: 27841348
    [TBL] [Abstract][Full Text] [Related]  

  • 14. CD45 pre-exclusion from the tips of T cell microvilli prior to antigen recognition.
    Jung Y; Wen L; Altman A; Ley K
    Nat Commun; 2021 Jun; 12(1):3872. PubMed ID: 34162836
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Expression of CD45 lacking the catalytic protein tyrosine phosphatase domain modulates Lck phosphorylation and T cell activation.
    Wang Y; Johnson P
    J Biol Chem; 2005 Apr; 280(14):14318-24. PubMed ID: 15687496
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Ligand-induced segregation from large cell-surface phosphatases is a critical step in γδ TCR triggering.
    Li F; Roy S; Niculcea J; Gould K; Adams EJ; van der Merwe PA; Choudhuri K
    bioRxiv; 2023 Aug; ():. PubMed ID: 37662246
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The catalytic activity of the CD45 membrane-proximal phosphatase domain is required for TCR signaling and regulation.
    Desai DM; Sap J; Silvennoinen O; Schlessinger J; Weiss A
    EMBO J; 1994 Sep; 13(17):4002-10. PubMed ID: 8076596
    [TBL] [Abstract][Full Text] [Related]  

  • 18. A sharp T-cell antigen receptor signaling threshold for T-cell proliferation.
    Au-Yeung BB; Zikherman J; Mueller JL; Ashouri JF; Matloubian M; Cheng DA; Chen Y; Shokat KM; Weiss A
    Proc Natl Acad Sci U S A; 2014 Sep; 111(35):E3679-88. PubMed ID: 25136127
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The CD45 tyrosine phosphatase regulates specific pools of antigen receptor-associated p59fyn and CD4-associated p56lck tyrosine in human T-cells.
    Biffen M; McMichael-Phillips D; Larson T; Venkitaraman A; Alexander D
    EMBO J; 1994 Apr; 13(8):1920-9. PubMed ID: 8168490
    [TBL] [Abstract][Full Text] [Related]  

  • 20. CD45-Csk phosphatase-kinase titration uncouples basal and inducible T cell receptor signaling during thymic development.
    Zikherman J; Jenne C; Watson S; Doan K; Raschke W; Goodnow CC; Weiss A
    Immunity; 2010 Mar; 32(3):342-54. PubMed ID: 20346773
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.