267 related articles for article (PubMed ID: 23580742)
1. Inhibition of late sodium current by mexiletine: a novel pharmotherapeutical approach in timothy syndrome.
Gao Y; Xue X; Hu D; Liu W; Yuan Y; Sun H; Li L; Timothy KW; Zhang L; Li C; Yan GX
Circ Arrhythm Electrophysiol; 2013 Jun; 6(3):614-22. PubMed ID: 23580742
[TBL] [Abstract][Full Text] [Related]
2. Timothy syndrome 1 genotype without syndactyly and major extracardiac manifestations.
Sepp R; Hategan L; Bácsi A; Cseklye J; Környei L; Borbás J; Széll M; Forster T; Nagy I; Hegedűs Z
Am J Med Genet A; 2017 Mar; 173(3):784-789. PubMed ID: 28211989
[TBL] [Abstract][Full Text] [Related]
3. Expanding the phenotype of Timothy syndrome type 2: an adolescent with ventricular fibrillation but normal development.
Hiippala A; Tallila J; Myllykangas S; Koskenvuo JW; Alastalo TP
Am J Med Genet A; 2015 Mar; 167A(3):629-34. PubMed ID: 25691416
[TBL] [Abstract][Full Text] [Related]
4. Novel long QT syndrome-associated missense mutation, L762F, in CACNA1C-encoded L-type calcium channel imparts a slower inactivation tau and increased sustained and window current.
Landstrom AP; Boczek NJ; Ye D; Miyake CY; De la Uz CM; Allen HD; Ackerman MJ; Kim JJ
Int J Cardiol; 2016 Oct; 220():290-8. PubMed ID: 27390944
[TBL] [Abstract][Full Text] [Related]
5. A case report: Is mexiletine usage effective in the shortening of QTC interval and improving the T-wave alternans in Timothy syndrome?
Tunca Sahin G; Ergul Y
Ann Noninvasive Electrocardiol; 2018 May; 23(3):e12522. PubMed ID: 29194862
[TBL] [Abstract][Full Text] [Related]
6. Long-term follow-up of a patient with type 2 Timothy syndrome and the partial efficacy of mexiletine.
Hermida A; Jedraszak G; Kubala M; Mathiron A; Berna P; Bennis Y; Hermida JS
Gene; 2021 Apr; 777():145465. PubMed ID: 33524520
[TBL] [Abstract][Full Text] [Related]
7. The role of mexiletine in the management of long QT syndrome.
Li G; Zhang L
J Electrocardiol; 2018; 51(6):1061-1065. PubMed ID: 30497731
[TBL] [Abstract][Full Text] [Related]
8. Gain-of-function mutations in the calcium channel CACNA1C (Cav1.2) cause non-syndromic long-QT but not Timothy syndrome.
Wemhöner K; Friedrich C; Stallmeyer B; Coffey AJ; Grace A; Zumhagen S; Seebohm G; Ortiz-Bonnin B; Rinné S; Sachse FB; Schulze-Bahr E; Decher N
J Mol Cell Cardiol; 2015 Mar; 80():186-95. PubMed ID: 25633834
[TBL] [Abstract][Full Text] [Related]
9. Long QT syndrome type 8: novel CACNA1C mutations causing QT prolongation and variant phenotypes.
Fukuyama M; Wang Q; Kato K; Ohno S; Ding WG; Toyoda F; Itoh H; Kimura H; Makiyama T; Ito M; Matsuura H; Horie M
Europace; 2014 Dec; 16(12):1828-37. PubMed ID: 24728418
[TBL] [Abstract][Full Text] [Related]
10. Normalization of ventricular repolarization with flecainide in long QT syndrome patients with SCN5A:DeltaKPQ mutation.
Windle JR; Geletka RC; Moss AJ; Zareba W; Atkins DL
Ann Noninvasive Electrocardiol; 2001 Apr; 6(2):153-8. PubMed ID: 11333173
[TBL] [Abstract][Full Text] [Related]
11. Maternal mosaicism confounds the neonatal diagnosis of type 1 Timothy syndrome.
Dufendach KA; Giudicessi JR; Boczek NJ; Ackerman MJ
Pediatrics; 2013 Jun; 131(6):e1991-5. PubMed ID: 23690510
[TBL] [Abstract][Full Text] [Related]
12. Effect of mexiletine on long QT syndrome model.
Wang HW; Zheng YQ; Yang ZF; Li CZ; Liu YM
Acta Pharmacol Sin; 2003 Apr; 24(4):316-20. PubMed ID: 12676070
[TBL] [Abstract][Full Text] [Related]
13. Unusual retrospective prenatal findings in a male newborn with Timothy syndrome type 1.
Corona-Rivera JR; Barrios-Prieto E; Nieto-García R; Bloise R; Priori S; Napolitano C; Bobadilla-Morales L; Corona-Rivera A; Zapata-Aldana E; Peña-Padilla C; Rivera-Vargas J; Chavana-Naranjo E
Eur J Med Genet; 2015; 58(6-7):332-5. PubMed ID: 25882468
[TBL] [Abstract][Full Text] [Related]
14. Geno- and phenotypic characteristics and clinical outcomes of
Borbás J; Vámos M; Hategan L; Hanák L; Farkas N; Szakács Z; Csupor D; Tél B; Kupó P; Csányi B; Nagy V; Komócsi A; Habon T; Hegyi P; Sepp R
Front Cardiovasc Med; 2022; 9():1021009. PubMed ID: 36523353
[TBL] [Abstract][Full Text] [Related]
15. Impaired chromaffin cell excitability and exocytosis in autistic Timothy syndrome TS2-neo mouse rescued by L-type calcium channel blockers.
Calorio C; Gavello D; Guarina L; Salio C; Sassoè-Pognetto M; Riganti C; Bianchi FT; Hofer NT; Tuluc P; Obermair GJ; Defilippi P; Balzac F; Turco E; Bett GC; Rasmusson RL; Carbone E
J Physiol; 2019 Mar; 597(6):1705-1733. PubMed ID: 30629744
[TBL] [Abstract][Full Text] [Related]
16. Complex interactions in a novel SCN5A compound mutation associated with long QT and Brugada syndrome: Implications for Na+ channel blocking pharmacotherapy for de novo conduction disease.
Liu J; Bayer JD; Aschar-Sobbi R; Wauchop M; Spears D; Gollob M; Vigmond EJ; Tsushima R; Backx PH; Chauhan VS
PLoS One; 2018; 13(5):e0197273. PubMed ID: 29791480
[TBL] [Abstract][Full Text] [Related]
17. Mexiletine Shortens the QT Interval in Patients With Potassium Channel-Mediated Type 2 Long QT Syndrome.
Bos JM; Crotti L; Rohatgi RK; Castelletti S; Dagradi F; Schwartz PJ; Ackerman MJ
Circ Arrhythm Electrophysiol; 2019 May; 12(5):e007280. PubMed ID: 31006312
[TBL] [Abstract][Full Text] [Related]
18. Incomplete Timothy syndrome secondary to a mosaic mutation of the CACNA1C gene diagnosed using next-generation sequencing.
Baurand A; Falcon-Eicher S; Laurent G; Villain E; Bonnet C; Thauvin-Robinet C; Jacquot C; Eicher JC; Gourraud JB; Schmitt S; Bézieau S; Giraud M; Dumont S; Kuentz P; Probst V; Burguet A; Kyndt F; Faivre L
Am J Med Genet A; 2017 Feb; 173(2):531-536. PubMed ID: 27868338
[TBL] [Abstract][Full Text] [Related]
19. Trafficking defects and gating abnormalities of a novel SCN5A mutation question gene-specific therapy in long QT syndrome type 3.
Ruan Y; Denegri M; Liu N; Bachetti T; Seregni M; Morotti S; Severi S; Napolitano C; Priori SG
Circ Res; 2010 Apr; 106(8):1374-83. PubMed ID: 20339117
[TBL] [Abstract][Full Text] [Related]
20. Dynamic analysis of the QT interval in long QT1 syndrome patients with a normal phenotype.
Lande G; Kyndt F; Baró I; Chabannes D; Boisseau P; Pony JC; Escande D; Le Marec H
Eur Heart J; 2001 Mar; 22(5):410-22. PubMed ID: 11207083
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]