BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

279 related articles for article (PubMed ID: 23583337)

  • 1. Functional deficit associated with a missense Werner syndrome mutation.
    Tadokoro T; Rybanska-Spaeder I; Kulikowicz T; Dawut L; Oshima J; Croteau DL; Bohr VA
    DNA Repair (Amst); 2013 Jun; 12(6):414-21. PubMed ID: 23583337
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Intrinsic ssDNA annealing activity in the C-terminal region of WRN.
    Muftuoglu M; Kulikowicz T; Beck G; Lee JW; Piotrowski J; Bohr VA
    Biochemistry; 2008 Sep; 47(39):10247-54. PubMed ID: 18771289
    [TBL] [Abstract][Full Text] [Related]  

  • 3. DNA binding residues in the RQC domain of Werner protein are critical for its catalytic activities.
    Tadokoro T; Kulikowicz T; Dawut L; Croteau DL; Bohr VA
    Aging (Albany NY); 2012 Jun; 4(6):417-29. PubMed ID: 22713343
    [TBL] [Abstract][Full Text] [Related]  

  • 4. WRN helicase defective in the premature aging disorder Werner syndrome genetically interacts with topoisomerase 3 and restores the top3 slow growth phenotype of sgs1 top3.
    Aggarwal M; Brosh RM
    Aging (Albany NY); 2009 Feb; 1(2):219-33. PubMed ID: 20157511
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The Drosophila orthologue of progeroid human WRN exonuclease, DmWRNexo, cleaves replication substrates but is inhibited by uracil or abasic sites : analysis of DmWRNexo activity in vitro.
    Mason PA; Boubriak I; Robbins T; Lasala R; Saunders R; Cox LS
    Age (Dordr); 2013 Jun; 35(3):793-806. PubMed ID: 22562358
    [TBL] [Abstract][Full Text] [Related]  

  • 6. WRN, the protein deficient in Werner syndrome, plays a critical structural role in optimizing DNA repair.
    Chen L; Huang S; Lee L; Davalos A; Schiestl RH; Campisi J; Oshima J
    Aging Cell; 2003 Aug; 2(4):191-9. PubMed ID: 12934712
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The clinical characteristics of Werner syndrome: molecular and biochemical diagnosis.
    Muftuoglu M; Oshima J; von Kobbe C; Cheng WH; Leistritz DF; Bohr VA
    Hum Genet; 2008 Nov; 124(4):369-77. PubMed ID: 18810497
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The Werner syndrome protein binds replication fork and holliday junction DNAs as an oligomer.
    Compton SA; Tolun G; Kamath-Loeb AS; Loeb LA; Griffith JD
    J Biol Chem; 2008 Sep; 283(36):24478-83. PubMed ID: 18596042
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Role of Werner syndrome gene product helicase in carcinogenesis and in resistance to genotoxins by cancer cells.
    Futami K; Ishikawa Y; Goto M; Furuichi Y; Sugimoto M
    Cancer Sci; 2008 May; 99(5):843-8. PubMed ID: 18312465
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Werner protein cooperates with the XRCC4-DNA ligase IV complex in end-processing.
    Kusumoto R; Dawut L; Marchetti C; Wan Lee J; Vindigni A; Ramsden D; Bohr VA
    Biochemistry; 2008 Jul; 47(28):7548-56. PubMed ID: 18558713
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Replication protein A stimulates the Werner syndrome protein branch migration activity.
    Sowd G; Wang H; Pretto D; Chazin WJ; Opresko PL
    J Biol Chem; 2009 Dec; 284(50):34682-91. PubMed ID: 19812417
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Werner syndrome (WRN) gene variants and their association with altered function and age-associated diseases.
    Lebel M; Monnat RJ
    Ageing Res Rev; 2018 Jan; 41():82-97. PubMed ID: 29146545
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Cooperation of DNA-PKcs and WRN helicase in the maintenance of telomeric D-loops.
    Kusumoto-Matsuo R; Opresko PL; Ramsden D; Tahara H; Bohr VA
    Aging (Albany NY); 2010 May; 2(5):274-84. PubMed ID: 20519774
    [TBL] [Abstract][Full Text] [Related]  

  • 14. DNA secondary structure of the released strand stimulates WRN helicase action on forked duplexes without coordinate action of WRN exonuclease.
    Ahn B; Bohr VA
    Biochem Biophys Res Commun; 2011 Aug; 411(4):684-9. PubMed ID: 21763283
    [TBL] [Abstract][Full Text] [Related]  

  • 15. A novel mutation of the WRN gene in a Chinese patient with Werner syndrome.
    Zhao N; Hao F; Qu T; Zuo YG; Wang BX
    Clin Exp Dermatol; 2008 May; 33(3):278-81. PubMed ID: 18205852
    [TBL] [Abstract][Full Text] [Related]  

  • 16. WRN mutations in Werner syndrome patients: genomic rearrangements, unusual intronic mutations and ethnic-specific alterations.
    Friedrich K; Lee L; Leistritz DF; Nürnberg G; Saha B; Hisama FM; Eyman DK; Lessel D; Nürnberg P; Li C; Garcia-F-Villalta MJ; Kets CM; Schmidtke J; Cruz VT; Van den Akker PC; Boak J; Peter D; Compoginis G; Cefle K; Ozturk S; López N; Wessel T; Poot M; Ippel PF; Groff-Kellermann B; Hoehn H; Martin GM; Kubisch C; Oshima J
    Hum Genet; 2010 Jul; 128(1):103-11. PubMed ID: 20443122
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Competition between the DNA unwinding and strand pairing activities of the Werner and Bloom syndrome proteins.
    Machwe A; Lozada EM; Xiao L; Orren DK
    BMC Mol Biol; 2006 Jan; 7():1. PubMed ID: 16412221
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Werner syndrome protein. I. DNA helicase and dna exonuclease reside on the same polypeptide.
    Shen JC; Gray MD; Oshima J; Kamath-Loeb AS; Fry M; Loeb LA
    J Biol Chem; 1998 Dec; 273(51):34139-44. PubMed ID: 9852073
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The Werner syndrome protein affects the expression of genes involved in adipogenesis and inflammation in addition to cell cycle and DNA damage responses.
    Turaga RV; Paquet ER; Sild M; Vignard J; Garand C; Johnson FB; Masson JY; Lebel M
    Cell Cycle; 2009 Jul; 8(13):2080-92. PubMed ID: 19502800
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Werner helicase wings DNA binding.
    Hoadley KA; Keck JL
    Structure; 2010 Feb; 18(2):149-51. PubMed ID: 20159459
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 14.