These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

155 related articles for article (PubMed ID: 23585833)

  • 1. Re-directing an alkylating agent to mitochondria alters drug target and cell death mechanism.
    Mourtada R; Fonseca SB; Wisnovsky SP; Pereira MP; Wang X; Hurren R; Parfitt J; Larsen L; Smith RA; Murphy MP; Schimmer AD; Kelley SO
    PLoS One; 2013; 8(4):e60253. PubMed ID: 23585833
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Structural modifications of mitochondria-targeted chlorambucil alter cell death mechanism but preserve MDR evasion.
    Jean SR; Pereira MP; Kelley SO
    Mol Pharm; 2014 Aug; 11(8):2675-82. PubMed ID: 24922525
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Bifunctional peptide hybrids targeting the matrix of mitochondria.
    Klimpel A; Neundorf I
    J Control Release; 2018 Dec; 291():147-156. PubMed ID: 30367921
    [TBL] [Abstract][Full Text] [Related]  

  • 4. A selective mitochondrial-targeted chlorambucil with remarkable cytotoxicity in breast and pancreatic cancers.
    Millard M; Gallagher JD; Olenyuk BZ; Neamati N
    J Med Chem; 2013 Nov; 56(22):9170-9. PubMed ID: 24147900
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Rerouting chlorambucil to mitochondria combats drug deactivation and resistance in cancer cells.
    Fonseca SB; Pereira MP; Mourtada R; Gronda M; Horton KL; Hurren R; Minden MD; Schimmer AD; Kelley SO
    Chem Biol; 2011 Apr; 18(4):445-53. PubMed ID: 21513881
    [TBL] [Abstract][Full Text] [Related]  

  • 6. A Prodrug of Two Approved Drugs, Cisplatin and Chlorambucil, for Chemo War Against Cancer.
    Pathak RK; Wen R; Kolishetti N; Dhar S
    Mol Cancer Ther; 2017 Apr; 16(4):625-636. PubMed ID: 28148716
    [TBL] [Abstract][Full Text] [Related]  

  • 7. A mitochondria-targeting heptamethine cyanine-chlorambucil formulated polymeric nanoparticle to potentiate native tumor chemotherapeutic efficacy.
    Liu J; Zhang J; Zhang Y; Wei W; Zhan M; Zhang Z; Liu B; Hu X; He W
    Biomater Sci; 2024 May; 12(10):2614-2625. PubMed ID: 38591255
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Novel molecular anti-colorectalcancer conjugate:chlorambucil-adipic acid dihydrizide-glutamine.
    Tabasi MA; Amanlou M; Siadat SD; Nourmohammadi Z; Omoomi FD; Ebrahimi SE; Aghasadeghi MR; Rahimi P; Pourhosseini S; Mehravi B; Ardestani MS
    Anticancer Agents Med Chem; 2013 Nov; 13(9):1449-59. PubMed ID: 23343080
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Reduced DNA double strand breaks in chlorambucil resistant cells are related to high DNA-PKcs activity and low oxidative stress.
    Boldogh I; Roy G; Lee MS; Bacsi A; Hazra TK; Bhakat KK; Das GC; Mitra S
    Toxicology; 2003 Nov; 193(1-2):137-52. PubMed ID: 14599773
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Scutellarein selectively targets multiple myeloma cells by increasing mitochondrial superoxide production and activating intrinsic apoptosis pathway.
    Shi L; Wu Y; Lv DL; Feng L
    Biomed Pharmacother; 2019 Jan; 109():2109-2118. PubMed ID: 30551468
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Characterization of a chlorambucil-resistant human ovarian carcinoma cell line overexpressing glutathione S-transferase mu.
    Horton JK; Roy G; Piper JT; Van Houten B; Awasthi YC; Mitra S; Alaoui-Jamali MA; Boldogh I; Singhal SS
    Biochem Pharmacol; 1999 Aug; 58(4):693-702. PubMed ID: 10413308
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Acquired alkylating drug resistance of a human ovarian carcinoma cell line is unaffected by altered levels of pro- and anti-apoptotic proteins.
    Roy G; Horton JK; Roy R; Denning T; Mitra S; Boldogh I
    Oncogene; 2000 Jan; 19(1):141-50. PubMed ID: 10644989
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Synthesis of a new conjugated polymer for DNA alkylation and gene regulation.
    Nie C; Zhu C; Feng L; Lv F; Liu L; Wang S
    ACS Appl Mater Interfaces; 2013 Jun; 5(11):4549-54. PubMed ID: 23548104
    [TBL] [Abstract][Full Text] [Related]  

  • 14. A Multi-Mitochondrial Anticancer Agent that Selectively Kills Cancer Cells and Overcomes Drug Resistance.
    Peng YB; Zhao ZL; Liu T; Xie GJ; Jin C; Deng TG; Sun Y; Li X; Hu XX; Zhang XB; Ye M; Tan WH
    ChemMedChem; 2017 Feb; 12(3):250-256. PubMed ID: 28098432
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Differentiation inducing factor 3 mediates its anti-leukemic effect through ROS-dependent DRP1-mediated mitochondrial fission and induction of caspase-independent cell death.
    Dubois A; Ginet C; Furstoss N; Belaid A; Hamouda MA; El Manaa W; Cluzeau T; Marchetti S; Ricci JE; Jacquel A; Luciano F; Driowya M; Benhida R; Auberger P; Robert G
    Oncotarget; 2016 May; 7(18):26120-36. PubMed ID: 27027430
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Targeted combinational therapy inducing mitochondrial dysfunction.
    Shin WS; Park SK; Verwilst P; Koo S; Lee JH; Chi SG; Kim JS
    Chem Commun (Camb); 2017 Jan; 53(7):1281-1284. PubMed ID: 28067351
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Chlorambucil in chronic lymphocytic leukemia: mechanism of action.
    Begleiter A; Mowat M; Israels LG; Johnston JB
    Leuk Lymphoma; 1996 Oct; 23(3-4):187-201. PubMed ID: 9031099
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Low dose triptolide reverses chemoresistance in adult acute lymphoblastic leukemia cells via reactive oxygen species generation and DNA damage response disruption.
    Zhao H; Shi P; Deng M; Jiang Z; Li Y; Kannappan V; Wang W; Li P; Xu B
    Oncotarget; 2016 Dec; 7(51):85515-85528. PubMed ID: 27888802
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Synthesis and in vitro efficacy of transferrin conjugates of the anticancer drug chlorambucil.
    Beyer U; Roth T; Schumacher P; Maier G; Unold A; Frahm AW; Fiebig HH; Unger C; Kratz F
    J Med Chem; 1998 Jul; 41(15):2701-8. PubMed ID: 9667961
    [TBL] [Abstract][Full Text] [Related]  

  • 20. 15d-PGJ2 induces apoptosis by reactive oxygen species-mediated inactivation of Akt in leukemia and colorectal cancer cells and shows in vivo antitumor activity.
    Shin SW; Seo CY; Han H; Han JY; Jeong JS; Kwak JY; Park JI
    Clin Cancer Res; 2009 Sep; 15(17):5414-25. PubMed ID: 19690198
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.