BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

234 related articles for article (PubMed ID: 23586323)

  • 21. [3H]dofetilide binding in SHSY5Y and HEK293 cells expressing a HERG-like K+ channel?
    Finlayson K; Pennington AJ; Kelly JS
    Eur J Pharmacol; 2001 Feb; 412(3):203-12. PubMed ID: 11166283
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Molecular determinants of inactivation and dofetilide block in ether a-go-go (EAG) channels and EAG-related K(+) channels.
    Ficker E; Jarolimek W; Brown AM
    Mol Pharmacol; 2001 Dec; 60(6):1343-8. PubMed ID: 11723241
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Mechanism of block and identification of the verapamil binding domain to HERG potassium channels.
    Zhang S; Zhou Z; Gong Q; Makielski JC; January CT
    Circ Res; 1999 May; 84(9):989-98. PubMed ID: 10325236
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Effect of terfenadine and pentamidine on the HERG channel and its intracellular trafficking: combined analysis with automated voltage clamp and confocal microscopy.
    Tanaka H; Takahashi Y; Hamaguchi S; Iida-Tanaka N; Oka T; Nishio M; Ohtsuki A; Namekata I
    Biol Pharm Bull; 2014; 37(11):1826-30. PubMed ID: 25366487
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Drug binding interactions in the inner cavity of HERG channels: molecular insights from structure-activity relationships of clofilium and ibutilide analogs.
    Perry M; Stansfeld PJ; Leaney J; Wood C; de Groot MJ; Leishman D; Sutcliffe MJ; Mitcheson JS
    Mol Pharmacol; 2006 Feb; 69(2):509-19. PubMed ID: 16291873
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Correlation between human ether-a-go-go-related gene channel inhibition and action potential prolongation.
    Saxena P; Hortigon-Vinagre MP; Beyl S; Baburin I; Andranovits S; Iqbal SM; Costa A; IJzerman AP; Kügler P; Timin E; Smith GL; Hering S
    Br J Pharmacol; 2017 Sep; 174(18):3081-3093. PubMed ID: 28681507
    [TBL] [Abstract][Full Text] [Related]  

  • 27. The Susceptibilities of Human Ether-à-Go-Go-Related Gene Channel with the G487R Mutation to Arrhythmogenic Factors.
    Hisajima N; Hata Y; Kinoshita K; Fukushima T; Nishida N; Kano M; Tabata T
    Biol Pharm Bull; 2015; 38(5):781-4. PubMed ID: 25947924
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Molecular determinants of HERG channel block.
    Kamiya K; Niwa R; Mitcheson JS; Sanguinetti MC
    Mol Pharmacol; 2006 May; 69(5):1709-16. PubMed ID: 16474003
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Functional Impact of BeKm-1, a High-Affinity hERG Blocker, on Cardiomyocytes Derived from Human-Induced Pluripotent Stem Cells.
    De Waard S; Montnach J; Ribeiro B; Nicolas S; Forest V; Charpentier F; Mangoni ME; Gaborit N; Ronjat M; Loussouarn G; Lemarchand P; De Waard M
    Int J Mol Sci; 2020 Sep; 21(19):. PubMed ID: 32998413
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Facilitation of
    Furutani K; Tsumoto K; Chen IS; Handa K; Yamakawa Y; Sack JT; Kurachi Y
    J Gen Physiol; 2019 Feb; 151(2):214-230. PubMed ID: 30674563
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Investigating dynamic protocol-dependence of hERG potassium channel inhibition at 37 degrees C: Cisapride versus dofetilide.
    Milnes JT; Witchel HJ; Leaney JL; Leishman DJ; Hancox JC
    J Pharmacol Toxicol Methods; 2010; 61(2):178-91. PubMed ID: 20172036
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Progesterone impairs human ether-a-go-go-related gene (HERG) trafficking by disruption of intracellular cholesterol homeostasis.
    Wu ZY; Yu DJ; Soong TW; Dawe GS; Bian JS
    J Biol Chem; 2011 Jun; 286(25):22186-94. PubMed ID: 21525004
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Dofetilide block involves interactions with open and inactivated states of HERG channels.
    Weerapura M; Hébert TE; Nattel S
    Pflugers Arch; 2002 Feb; 443(4):520-31. PubMed ID: 11907818
    [TBL] [Abstract][Full Text] [Related]  

  • 34. In silico prediction of the chemical block of human ether-a-go-go-related gene (hERG) K+ current.
    Inanobe A; Kamiya N; Murakami S; Fukunishi Y; Nakamura H; Kurachi Y
    J Physiol Sci; 2008 Dec; 58(7):459-70. PubMed ID: 19032804
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Comparison of the effects of DC031050, a class III antiarrhythmic agent, on hERG channel and three neuronal potassium channels.
    Li P; Sun HF; Zhou PZ; Ma CY; Hu GY; Jiang HL; Li M; Liu H; Gao ZB
    Acta Pharmacol Sin; 2012 Jun; 33(6):728-36. PubMed ID: 22609836
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Altering extracellular potassium concentration does not modulate drug block of human ether-a-go-go-related gene (hERG) channels.
    Limberis JT; Su Z; Cox BF; Gintant GA; Martin RL
    Clin Exp Pharmacol Physiol; 2006 Nov; 33(11):1059-65. PubMed ID: 17042915
    [TBL] [Abstract][Full Text] [Related]  

  • 37. The cardiac hERG/IKr potassium channel as pharmacological target: structure, function, regulation, and clinical applications.
    Thomas D; Karle CA; Kiehn J
    Curr Pharm Des; 2006; 12(18):2271-83. PubMed ID: 16787254
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Inactivation gating determines drug potency: a common mechanism for drug blockade of HERG channels.
    Yang BF; Xu DH; Xu CQ; Li Z; Du ZM; Wang HZ; Dong DL
    Acta Pharmacol Sin; 2004 May; 25(5):554-60. PubMed ID: 15132818
    [TBL] [Abstract][Full Text] [Related]  

  • 39. [HERG K+ channel, the target of anti-arrhythmias drugs].
    Guan FY; Yang SJ
    Yao Xue Xue Bao; 2007 Jul; 42(7):687-91. PubMed ID: 17882949
    [TBL] [Abstract][Full Text] [Related]  

  • 40. A mechanism for the proarrhythmic effects of cisapride (Propulsid): high affinity blockade of the human cardiac potassium channel HERG.
    Rampe D; Roy ML; Dennis A; Brown AM
    FEBS Lett; 1997 Nov; 417(1):28-32. PubMed ID: 9395068
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 12.