These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

184 related articles for article (PubMed ID: 23588318)

  • 1. Transporter studies in drug development: experience to date and follow-up on decision trees from the International Transporter Consortium.
    Tweedie D; Polli JW; Berglund EG; Huang SM; Zhang L; Poirier A; Chu X; Feng B;
    Clin Pharmacol Ther; 2013 Jul; 94(1):113-25. PubMed ID: 23588318
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Highlights from the International Transporter Consortium second workshop.
    Zamek-Gliszczynski MJ; Hoffmaster KA; Tweedie DJ; Giacomini KM; Hillgren KM
    Clin Pharmacol Ther; 2012 Nov; 92(5):553-6. PubMed ID: 23085880
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Emerging transporters of clinical importance: an update from the International Transporter Consortium.
    Hillgren KM; Keppler D; Zur AA; Giacomini KM; Stieger B; Cass CE; Zhang L;
    Clin Pharmacol Ther; 2013 Jul; 94(1):52-63. PubMed ID: 23588305
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Beyond the ITC White Paper: emerging sciences in drug transporters and opportunities for drug development.
    Lai Y; Hsiao P
    Curr Pharm Des; 2014; 20(10):1577-94. PubMed ID: 23789952
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Evaluation of a New Molecular Entity as a Victim of Metabolic Drug-Drug Interactions-an Industry Perspective.
    Bohnert T; Patel A; Templeton I; Chen Y; Lu C; Lai G; Leung L; Tse S; Einolf HJ; Wang YH; Sinz M; Stearns R; Walsky R; Geng W; Sudsakorn S; Moore D; He L; Wahlstrom J; Keirns J; Narayanan R; Lang D; Yang X;
    Drug Metab Dispos; 2016 Aug; 44(8):1399-423. PubMed ID: 27052879
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Transporters in Drug Development: 2018 ITC Recommendations for Transporters of Emerging Clinical Importance.
    Zamek-Gliszczynski MJ; Taub ME; Chothe PP; Chu X; Giacomini KM; Kim RB; Ray AS; Stocker SL; Unadkat JD; Wittwer MB; Xia C; Yee SW; Zhang L; Zhang Y;
    Clin Pharmacol Ther; 2018 Nov; 104(5):890-899. PubMed ID: 30091177
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Influence of Transporter Polymorphisms on Drug Disposition and Response: A Perspective From the International Transporter Consortium.
    Yee SW; Brackman DJ; Ennis EA; Sugiyama Y; Kamdem LK; Blanchard R; Galetin A; Zhang L; Giacomini KM
    Clin Pharmacol Ther; 2018 Nov; 104(5):803-817. PubMed ID: 29679469
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Transporter pharmacogenetics: do we need function? Do we need motion?
    Pastor-Anglada M
    Pharmacogenomics; 2013 Oct; 14(13):1537-40. PubMed ID: 24088123
    [No Abstract]   [Full Text] [Related]  

  • 9. Impact of hepatic uptake transporters on pharmacokinetics and drug-drug interactions: use of assays and models for decision making in the pharmaceutical industry.
    Soars MG; Webborn PJ; Riley RJ
    Mol Pharm; 2009; 6(6):1662-77. PubMed ID: 19402709
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Membrane transporters in drug development.
    Keogh JP
    Adv Pharmacol; 2012; 63():1-42. PubMed ID: 22776638
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Biomarkers for In Vivo Assessment of Transporter Function.
    Müller F; Sharma A; König J; Fromm MF
    Pharmacol Rev; 2018 Apr; 70(2):246-277. PubMed ID: 29487084
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Transporter biology in drug approval: regulatory aspects.
    Maeda K; Sugiyama Y
    Mol Aspects Med; 2013; 34(2-3):711-8. PubMed ID: 23506904
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Membrane transporters in drug development.
    ; Giacomini KM; Huang SM; Tweedie DJ; Benet LZ; Brouwer KL; Chu X; Dahlin A; Evers R; Fischer V; Hillgren KM; Hoffmaster KA; Ishikawa T; Keppler D; Kim RB; Lee CA; Niemi M; Polli JW; Sugiyama Y; Swaan PW; Ware JA; Wright SH; Yee SW; Zamek-Gliszczynski MJ; Zhang L
    Nat Rev Drug Discov; 2010 Mar; 9(3):215-36. PubMed ID: 20190787
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Transporter assays as useful in vitro tools in drug discovery and development.
    Volpe DA
    Expert Opin Drug Discov; 2016; 11(1):91-103. PubMed ID: 26512742
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Evaluation of drug transporter interactions in drug discovery and development.
    Lai Y; Sampson KE; Stevens JC
    Comb Chem High Throughput Screen; 2010 Feb; 13(2):112-34. PubMed ID: 20053160
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Application of PBPK modelling in drug discovery and development at Pfizer.
    Jones HM; Dickins M; Youdim K; Gosset JR; Attkins NJ; Hay TL; Gurrell IK; Logan YR; Bungay PJ; Jones BC; Gardner IB
    Xenobiotica; 2012 Jan; 42(1):94-106. PubMed ID: 22035569
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Predicting human hepatic clearance from in vitro drug metabolism and transport data: a scientific and pharmaceutical perspective for assessing drug-drug interactions.
    Camenisch G; Umehara K
    Biopharm Drug Dispos; 2012 May; 33(4):179-94. PubMed ID: 22407504
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Absolute abundance and function of intestinal drug transporters: a prerequisite for fully mechanistic in vitro-in vivo extrapolation of oral drug absorption.
    Harwood MD; Neuhoff S; Carlson GL; Warhurst G; Rostami-Hodjegan A
    Biopharm Drug Dispos; 2013 Jan; 34(1):2-28. PubMed ID: 22927116
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Drug trafficking: recent advances in therapeutics and disease.
    Sprowl JA; Sparreboom A
    Clin Pharmacol Ther; 2012 Nov; 92(5):531-4. PubMed ID: 23085872
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Implications of endogenous roles of transporters for drug discovery: hitchhiking and metabolite-likeness.
    Kell DB
    Nat Rev Drug Discov; 2016 Feb; 15(2):143. PubMed ID: 26837595
    [No Abstract]   [Full Text] [Related]  

    [Next]    [New Search]
    of 10.