394 related articles for article (PubMed ID: 23588320)
1. Intracellular drug concentrations and transporters: measurement, modeling, and implications for the liver.
Chu X; Korzekwa K; Elsby R; Fenner K; Galetin A; Lai Y; Matsson P; Moss A; Nagar S; Rosania GR; Bai JP; Polli JW; Sugiyama Y; Brouwer KL;
Clin Pharmacol Ther; 2013 Jul; 94(1):126-41. PubMed ID: 23588320
[TBL] [Abstract][Full Text] [Related]
2. Liver transporters in hepatic drug disposition: an update.
Li P; Wang GJ; Robertson TA; Roberts MS
Curr Drug Metab; 2009 Jun; 10(5):482-98. PubMed ID: 19689245
[TBL] [Abstract][Full Text] [Related]
3. Importance of Hepatic Transporters in Clinical Disposition of Drugs and Their Metabolites.
Patel M; Taskar KS; Zamek-Gliszczynski MJ
J Clin Pharmacol; 2016 Jul; 56 Suppl 7():S23-39. PubMed ID: 27385177
[TBL] [Abstract][Full Text] [Related]
4. A perspective on efflux transport proteins in the liver.
Köck K; Brouwer KL
Clin Pharmacol Ther; 2012 Nov; 92(5):599-612. PubMed ID: 22948894
[TBL] [Abstract][Full Text] [Related]
5. Sandwich-Cultured Hepatocytes for Mechanistic Understanding of Hepatic Disposition of Parent Drugs and Metabolites by Transporter-Enzyme Interplay.
Matsunaga N; Fukuchi Y; Imawaka H; Tamai I
Drug Metab Dispos; 2018 May; 46(5):680-691. PubMed ID: 29352067
[TBL] [Abstract][Full Text] [Related]
6. Understanding the Interplay Between Uptake and Efflux Transporters Within In Vitro Systems in Defining Hepatocellular Drug Concentrations.
Cantrill C; Houston JB
J Pharm Sci; 2017 Sep; 106(9):2815-2825. PubMed ID: 28478131
[TBL] [Abstract][Full Text] [Related]
7. Prediction of Hepatic Efflux Transporter-Mediated Drug Interactions: When Is it Optimal to Measure Intracellular Unbound Fraction of Inhibitors?
Guo C; Yang K; Liao M; Xia CQ; Brouwer KR; Brouwer KLR
J Pharm Sci; 2017 Sep; 106(9):2401-2406. PubMed ID: 28465154
[TBL] [Abstract][Full Text] [Related]
8. Drug transport proteins in the liver.
Faber KN; Müller M; Jansen PL
Adv Drug Deliv Rev; 2003 Jan; 55(1):107-24. PubMed ID: 12535576
[TBL] [Abstract][Full Text] [Related]
9. Primary hepatocyte cultures as prominent in vitro tools to study hepatic drug transporters.
Ramboer E; Vanhaecke T; Rogiers V; Vinken M
Drug Metab Rev; 2013 May; 45(2):196-217. PubMed ID: 23368091
[TBL] [Abstract][Full Text] [Related]
10. ITC recommendations for transporter kinetic parameter estimation and translational modeling of transport-mediated PK and DDIs in humans.
Zamek-Gliszczynski MJ; Lee CA; Poirier A; Bentz J; Chu X; Ellens H; Ishikawa T; Jamei M; Kalvass JC; Nagar S; Pang KS; Korzekwa K; Swaan PW; Taub ME; Zhao P; Galetin A;
Clin Pharmacol Ther; 2013 Jul; 94(1):64-79. PubMed ID: 23588311
[TBL] [Abstract][Full Text] [Related]
11. In Vitro Interactions of Epacadostat and its Major Metabolites with Human Efflux and Uptake Transporters: Implications for Pharmacokinetics and Drug Interactions.
Zhang Q; Zhang Y; Boer J; Shi JG; Hu P; Diamond S; Yeleswaram S
Drug Metab Dispos; 2017 Jun; 45(6):612-623. PubMed ID: 28283500
[TBL] [Abstract][Full Text] [Related]
12. Prediction of pharmacokinetics and drug-drug interactions when hepatic transporters are involved.
Li R; Barton HA; Varma MV
Clin Pharmacokinet; 2014 Aug; 53(8):659-78. PubMed ID: 25056496
[TBL] [Abstract][Full Text] [Related]
13. Membrane transport as a determinant of the hepatic elimination of drugs and metabolites.
Evans AM
Clin Exp Pharmacol Physiol; 1996; 23(10-11):970-4. PubMed ID: 8911743
[TBL] [Abstract][Full Text] [Related]
14. Protein-protein interactions of drug uptake transporters that are important for liver and kidney.
Zhang Y; Hagenbuch B
Biochem Pharmacol; 2019 Oct; 168():384-391. PubMed ID: 31381872
[TBL] [Abstract][Full Text] [Related]
15. Transport vs. Metabolism: What Determines the Pharmacokinetics and Pharmacodynamics of Drugs? Insights From the Extended Clearance Model.
Patilea-Vrana G; Unadkat JD
Clin Pharmacol Ther; 2016 Nov; 100(5):413-418. PubMed ID: 27448198
[TBL] [Abstract][Full Text] [Related]
16. Pharmacokinetic modeling of the hepatobiliary transport mediated by cooperation of uptake and efflux transporters.
Kusuhara H; Sugiyama Y
Drug Metab Rev; 2010 Aug; 42(3):539-50. PubMed ID: 20175646
[TBL] [Abstract][Full Text] [Related]
17. Analysis of Sinusoidal Drug Uptake Transporter Activities in Primary Human Hepatocytes.
Le Vée M; Jouan E; Denizot C; Parmentier Y; Fardel O
Methods Mol Biol; 2015; 1250():287-302. PubMed ID: 26272151
[TBL] [Abstract][Full Text] [Related]
18. Impact of hepatic uptake transporters on pharmacokinetics and drug-drug interactions: use of assays and models for decision making in the pharmaceutical industry.
Soars MG; Webborn PJ; Riley RJ
Mol Pharm; 2009; 6(6):1662-77. PubMed ID: 19402709
[TBL] [Abstract][Full Text] [Related]
19. Drug transporters in pharmacokinetics.
Petzinger E; Geyer J
Naunyn Schmiedebergs Arch Pharmacol; 2006 Mar; 372(6):465-75. PubMed ID: 16532306
[TBL] [Abstract][Full Text] [Related]
20. In vitro and in vivo approaches to characterize transporter-mediated disposition in drug discovery.
Feng B; Varma MV; Costales C; Zhang H; Tremaine L
Expert Opin Drug Discov; 2014 Aug; 9(8):873-90. PubMed ID: 24857286
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]