647 related articles for article (PubMed ID: 23593036)
1. Functional IL6R 358Ala allele impairs classical IL-6 receptor signaling and influences risk of diverse inflammatory diseases.
Ferreira RC; Freitag DF; Cutler AJ; Howson JM; Rainbow DB; Smyth DJ; Kaptoge S; Clarke P; Boreham C; Coulson RM; Pekalski ML; Chen WM; Onengut-Gumuscu S; Rich SS; Butterworth AS; Malarstig A; Danesh J; Todd JA
PLoS Genet; 2013 Apr; 9(4):e1003444. PubMed ID: 23593036
[TBL] [Abstract][Full Text] [Related]
2. A functional IL-6 receptor (IL6R) variant is a risk factor for persistent atopic dermatitis.
Esparza-Gordillo J; Schaarschmidt H; Liang L; Cookson W; Bauerfeind A; Lee-Kirsch MA; Nemat K; Henderson J; Paternoster L; Harper JI; Mangold E; Nothen MM; Rüschendorf F; Kerscher T; Marenholz I; Matanovic A; Lau S; Keil T; Bauer CP; Kurek M; Ciechanowicz A; Macek M; Franke A; Kabesch M; Hubner N; Abecasis G; Weidinger S; Moffatt M; Lee YA
J Allergy Clin Immunol; 2013 Aug; 132(2):371-7. PubMed ID: 23582566
[TBL] [Abstract][Full Text] [Related]
3. The interleukin-6 receptor Asp358Ala single nucleotide polymorphism rs2228145 confers increased proteolytic conversion rates by ADAM proteases.
Garbers C; Monhasery N; Aparicio-Siegmund S; Lokau J; Baran P; Nowell MA; Jones SA; Rose-John S; Scheller J
Biochim Biophys Acta; 2014 Sep; 1842(9):1485-94. PubMed ID: 24878322
[TBL] [Abstract][Full Text] [Related]
4. The IL-6-neutralizing sIL-6R-sgp130 buffer system is disturbed in patients with type 2 diabetes.
Aparicio-Siegmund S; Garbers Y; Flynn CM; Waetzig GH; Gouni-Berthold I; Krone W; Berthold HK; Laudes M; Rose-John S; Garbers C
Am J Physiol Endocrinol Metab; 2019 Aug; 317(2):E411-E420. PubMed ID: 31237452
[TBL] [Abstract][Full Text] [Related]
5. Interleukin-6 receptor pathways in coronary heart disease: a collaborative meta-analysis of 82 studies.
; Sarwar N; Butterworth AS; Freitag DF; Gregson J; Willeit P; Gorman DN; Gao P; Saleheen D; Rendon A; Nelson CP; Braund PS; Hall AS; Chasman DI; Tybjærg-Hansen A; Chambers JC; Benjamin EJ; Franks PW; Clarke R; Wilde AA; Trip MD; Steri M; Witteman JC; Qi L; van der Schoot CE; de Faire U; Erdmann J; Stringham HM; Koenig W; Rader DJ; Melzer D; Reich D; Psaty BM; Kleber ME; Panagiotakos DB; Willeit J; Wennberg P; Woodward M; Adamovic S; Rimm EB; Meade TW; Gillum RF; Shaffer JA; Hofman A; Onat A; Sundström J; Wassertheil-Smoller S; Mellström D; Gallacher J; Cushman M; Tracy RP; Kauhanen J; Karlsson M; Salonen JT; Wilhelmsen L; Amouyel P; Cantin B; Best LG; Ben-Shlomo Y; Manson JE; Davey-Smith G; de Bakker PI; O'Donnell CJ; Wilson JF; Wilson AG; Assimes TL; Jansson JO; Ohlsson C; Tivesten Å; Ljunggren Ö; Reilly MP; Hamsten A; Ingelsson E; Cambien F; Hung J; Thomas GN; Boehnke M; Schunkert H; Asselbergs FW; Kastelein JJ; Gudnason V; Salomaa V; Harris TB; Kooner JS; Allin KH; Nordestgaard BG; Hopewell JC; Goodall AH; Ridker PM; Hólm H; Watkins H; Ouwehand WH; Samani NJ; Kaptoge S; Di Angelantonio E; Harari O; Danesh J
Lancet; 2012 Mar; 379(9822):1205-13. PubMed ID: 22421339
[TBL] [Abstract][Full Text] [Related]
6. A new regulatory variant in the interleukin-6 receptor gene associates with asthma risk.
Revez JA; Bain L; Chapman B; Powell JE; Jansen R; Duffy DL; Tung JY; ; Penninx BW; Visscher PM; De Geus EJ; Boomsma DI; Hinds DA; Martin NG; Montgomery GW; Ferreira MA
Genes Immun; 2013 Oct; 14(7):441-6. PubMed ID: 23945879
[TBL] [Abstract][Full Text] [Related]
7. Interleukin-6 Receptor Signaling and Abdominal Aortic Aneurysm Growth Rates.
Paige E; Clément M; Lareyre F; Sweeting M; Raffort J; Grenier C; Finigan A; Harrison J; Peters JE; Sun BB; Butterworth AS; Harrison SC; Bown MJ; Lindholt JS; Badger SA; Kullo IJ; Powell J; Norman PE; Scott DJA; Bailey MA; Rose-John S; Danesh J; Freitag DF; Paul DS; Mallat Z
Circ Genom Precis Med; 2019 Feb; 12(2):e002413. PubMed ID: 30657332
[TBL] [Abstract][Full Text] [Related]
8. The IL6R variation Asp(358)Ala is a potential modifier of lung function in subjects with asthma.
Hawkins GA; Robinson MB; Hastie AT; Li X; Li H; Moore WC; Howard TD; Busse WW; Erzurum SC; Wenzel SE; Peters SP; Meyers DA; Bleecker ER;
J Allergy Clin Immunol; 2012 Aug; 130(2):510-5.e1. PubMed ID: 22554704
[TBL] [Abstract][Full Text] [Related]
9. Interleukin-6 receptor pathways in abdominal aortic aneurysm.
Harrison SC; Smith AJ; Jones GT; Swerdlow DI; Rampuri R; Bown MJ; ; Folkersen L; Baas AF; de Borst GJ; Blankensteijn JD; Price JF; van der Graaf Y; McLachlan S; Agu O; Hofman A; Uitterlinden AG; Franco-Cereceda A; Ruigrok YM; van't Hof FN; Powell JT; van Rij AM; Casas JP; Eriksson P; Holmes MV; Asselbergs FW; Hingorani AD; Humphries SE
Eur Heart J; 2013 Dec; 34(48):3707-16. PubMed ID: 23111417
[TBL] [Abstract][Full Text] [Related]
10. The contribution of the functional IL6R polymorphism rs2228145, eQTLs and other genome-wide SNPs to the heritability of plasma sIL-6R levels.
van Dongen J; Jansen R; Smit D; Hottenga JJ; Mbarek H; Willemsen G; Kluft C; ; Penninx BW; Ferreira MA; Boomsma DI; de Geus EJ
Behav Genet; 2014 Jul; 44(4):368-82. PubMed ID: 24791950
[TBL] [Abstract][Full Text] [Related]
11. A common variant of the interleukin 6 receptor (IL-6r) gene increases IL-6r and IL-6 levels, without other inflammatory effects.
Rafiq S; Frayling TM; Murray A; Hurst A; Stevens K; Weedon MN; Henley W; Ferrucci L; Bandinelli S; Corsi AM; Guralnik JM; Melzer D
Genes Immun; 2007 Oct; 8(7):552-9. PubMed ID: 17671508
[TBL] [Abstract][Full Text] [Related]
12. The IL6R gene polymorphisms are associated with sIL-6R, IgE and lung function in Chinese patients with asthma.
Wang Y; Hu H; Wu J; Zhao X; Zhen Y; Wang S; Li W; Liang M; Wu B; Ma G
Gene; 2016 Jul; 585(1):51-57. PubMed ID: 26997259
[TBL] [Abstract][Full Text] [Related]
13. Activation of Toll-like Receptor 2 (TLR2) induces Interleukin-6 trans-signaling.
Flynn CM; Garbers Y; Lokau J; Wesch D; Schulte DM; Laudes M; Lieb W; Aparicio-Siegmund S; Garbers C
Sci Rep; 2019 May; 9(1):7306. PubMed ID: 31086276
[TBL] [Abstract][Full Text] [Related]
14. Differential regulation of neutrophil-activating chemokines by IL-6 and its soluble receptor isoforms.
McLoughlin RM; Hurst SM; Nowell MA; Harris DA; Horiuchi S; Morgan LW; Wilkinson TS; Yamamoto N; Topley N; Jones SA
J Immunol; 2004 May; 172(9):5676-83. PubMed ID: 15100312
[TBL] [Abstract][Full Text] [Related]
15. The balance of interleukin (IL)-6, IL-6·soluble IL-6 receptor (sIL-6R), and IL-6·sIL-6R·sgp130 complexes allows simultaneous classic and trans-signaling.
Baran P; Hansen S; Waetzig GH; Akbarzadeh M; Lamertz L; Huber HJ; Ahmadian MR; Moll JM; Scheller J
J Biol Chem; 2018 May; 293(18):6762-6775. PubMed ID: 29559558
[TBL] [Abstract][Full Text] [Related]
16. Shedding of Endogenous Interleukin-6 Receptor (IL-6R) Is Governed by A Disintegrin and Metalloproteinase (ADAM) Proteases while a Full-length IL-6R Isoform Localizes to Circulating Microvesicles.
Schumacher N; Meyer D; Mauermann A; von der Heyde J; Wolf J; Schwarz J; Knittler K; Murphy G; Michalek M; Garbers C; Bartsch JW; Guo S; Schacher B; Eickholz P; Chalaris A; Rose-John S; Rabe B
J Biol Chem; 2015 Oct; 290(43):26059-71. PubMed ID: 26359498
[TBL] [Abstract][Full Text] [Related]
17. An intermediate-risk multiple myeloma subgroup is defined by sIL-6r: levels synergistically increase with incidence of SNP rs2228145 and 1q21 amplification.
Stephens OW; Zhang Q; Qu P; Zhou Y; Chavan S; Tian E; Williams DR; Epstein J; Barlogie B; Shaughnessy JD
Blood; 2012 Jan; 119(2):503-12. PubMed ID: 22072558
[TBL] [Abstract][Full Text] [Related]
18. Association of plasma IL-6 and soluble IL-6 receptor levels with the Asp358Ala polymorphism of the IL-6 receptor gene in schizophrenic patients.
Sasayama D; Wakabayashi C; Hori H; Teraishi T; Hattori K; Ota M; Ishikawa M; Arima K; Higuchi T; Amano N; Kunugi H
J Psychiatr Res; 2011 Nov; 45(11):1439-44. PubMed ID: 21700295
[TBL] [Abstract][Full Text] [Related]
19. Association between a functional interleukin 6 receptor genetic variant and risk of depression and psychosis in a population-based birth cohort.
Khandaker GM; Zammit S; Burgess S; Lewis G; Jones PB
Brain Behav Immun; 2018 Mar; 69():264-272. PubMed ID: 29197507
[TBL] [Abstract][Full Text] [Related]
20. Regulation of soluble interleukin-6 (IL-6) receptor release from corneal epithelial cells and its role in the ocular surface.
Sugaya S; Sakimoto T; Shoji J; Sawa M
Jpn J Ophthalmol; 2011 May; 55(3):277-282. PubMed ID: 21523377
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]