BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

192 related articles for article (PubMed ID: 23593218)

  • 21. Midface and upper airway dysgenesis in FGFR2-related craniosynostosis involves multiple tissue-specific and cell cycle effects.
    Holmes G; O'Rourke C; Motch Perrine SM; Lu N; van Bakel H; Richtsmeier JT; Jabs EW
    Development; 2018 Oct; 145(19):. PubMed ID: 30228104
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Excessive osteoclast activation by osteoblast paracrine factor RANKL is a major cause of the abnormal long bone phenotype in Apert syndrome model mice.
    Shin HR; Kim BS; Kim HJ; Yoon H; Kim WJ; Choi JY; Ryoo HM
    J Cell Physiol; 2022 Apr; 237(4):2155-2168. PubMed ID: 35048384
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Morphological comparison of the craniofacial phenotypes of mouse models expressing the Apert FGFR2 S252W mutation in neural crest- or mesoderm-derived tissues.
    Heuzé Y; Singh N; Basilico C; Jabs EW; Holmes G; Richtsmeier JT
    Bone; 2014 Jun; 63():101-9. PubMed ID: 24632501
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Inhibited Wnt signaling causes age-dependent abnormalities in the bone matrix mineralization in the Apert syndrome FGFR2(S252W/+) mice.
    Zhang L; Chen P; Chen L; Weng T; Zhang S; Zhou X; Zhang B; Liu L
    PLoS One; 2015; 10(2):e112716. PubMed ID: 25693202
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Cell Type-Dependent Nonspecific Fibroblast Growth Factor Signaling in Apert Syndrome.
    Yeh E; Atique R; Fanganiello RD; Sunaga DY; Ishiy FA; Passos-Bueno MR
    Stem Cells Dev; 2016 Aug; 25(16):1249-60. PubMed ID: 27339175
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Functional characterization of a novel FGFR2 mutation, E731K, in craniosynostosis.
    Park J; Park OJ; Yoon WJ; Kim HJ; Choi KY; Cho TJ; Ryoo HM
    J Cell Biochem; 2012 Feb; 113(2):457-64. PubMed ID: 21928350
    [TBL] [Abstract][Full Text] [Related]  

  • 27. A Ser252Trp substitution in mouse FGFR2 results in hyperplasia of embryonic salivary gland parenchyma.
    Watanabe T; Kometani-Gunjigake K; Nakao-Kuroishi K; Ito-Sago M; Mizuhara M; Iwata D; Moriyama K; Ono K; Kawamoto T
    J Oral Biosci; 2021 Jun; 63(2):184-191. PubMed ID: 33684522
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Dura in the pathogenesis of syndromic craniosynostosis: fibroblast growth factor receptor 2 mutations in dural cells promote osteogenic proliferation and differentiation of osteoblasts.
    Ang BU; Spivak RM; Nah HD; Kirschner RE
    J Craniofac Surg; 2010 Mar; 21(2):462-7. PubMed ID: 20489451
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Increased EFG- and PDGFalpha-receptor signaling by mutant FGF-receptor 2 contributes to osteoblast dysfunction in Apert craniosynostosis.
    Miraoui H; Ringe J; Häupl T; Marie PJ
    Hum Mol Genet; 2010 May; 19(9):1678-89. PubMed ID: 20124286
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Apert p.Ser252Trp mutation in FGFR2 alters osteogenic potential and gene expression of cranial periosteal cells.
    Fanganiello RD; Sertié AL; Reis EM; Yeh E; Oliveira NA; Bueno DF; Kerkis I; Alonso N; Cavalheiro S; Matsushita H; Freitas R; Verjovski-Almeida S; Passos-Bueno MR
    Mol Med; 2007; 13(7-8):422-42. PubMed ID: 17622301
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Mandibular dysmorphology due to abnormal embryonic osteogenesis in FGFR2-related craniosynostosis mice.
    Motch Perrine SM; Wu M; Stephens NB; Kriti D; van Bakel H; Jabs EW; Richtsmeier JT
    Dis Model Mech; 2019 May; 12(5):. PubMed ID: 31064775
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Presence of the Apert canonical S252W FGFR2 mutation in a patient without severe syndactyly.
    Passos-Bueno MR; Richieri-Costa A; Sertié AL; Kneppers A
    J Med Genet; 1998 Aug; 35(8):677-9. PubMed ID: 9719378
    [TBL] [Abstract][Full Text] [Related]  

  • 33. From shape to cells: mouse models reveal mechanisms altering palate development in Apert syndrome.
    Martínez-Abadías N; Holmes G; Pankratz T; Wang Y; Zhou X; Jabs EW; Richtsmeier JT
    Dis Model Mech; 2013 May; 6(3):768-79. PubMed ID: 23519026
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Maldevelopment of the submandibular gland in a mouse model of apert syndrome.
    Yamaji K; Morita J; Watanabe T; Gunjigake K; Nakatomi M; Shiga M; Ono K; Moriyama K; Kawamoto T
    Dev Dyn; 2018 Nov; 247(11):1175-1185. PubMed ID: 30251381
    [TBL] [Abstract][Full Text] [Related]  

  • 35. RNA interference and inhibition of MEK-ERK signaling prevent abnormal skeletal phenotypes in a mouse model of craniosynostosis.
    Shukla V; Coumoul X; Wang RH; Kim HS; Deng CX
    Nat Genet; 2007 Sep; 39(9):1145-50. PubMed ID: 17694057
    [TBL] [Abstract][Full Text] [Related]  

  • 36. FGFR2 mutation in a patient with Apert syndrome associated with humeroradial synostosis.
    Kanauchi Y; Muragaki Y; Ogino T; Takahara M; Tsuchida H; Ishigaki D
    Congenit Anom (Kyoto); 2003 Dec; 43(4):302-5. PubMed ID: 15041782
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Abnormalities in cartilage and bone development in the Apert syndrome FGFR2(+/S252W) mouse.
    Wang Y; Xiao R; Yang F; Karim BO; Iacovelli AJ; Cai J; Lerner CP; Richtsmeier JT; Leszl JM; Hill CA; Yu K; Ornitz DM; Elisseeff J; Huso DL; Jabs EW
    Development; 2005 Aug; 132(15):3537-48. PubMed ID: 15975938
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Brain phenotypes in two FGFR2 mouse models for Apert syndrome.
    Aldridge K; Hill CA; Austin JR; Percival C; Martinez-Abadias N; Neuberger T; Wang Y; Jabs EW; Richtsmeier JT
    Dev Dyn; 2010 Mar; 239(3):987-97. PubMed ID: 20077479
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Facial suture synostosis of newborn Fgfr1(P250R/+) and Fgfr2(S252W/+) mouse models of Pfeiffer and Apert syndromes.
    Purushothaman R; Cox TC; Maga AM; Cunningham ML
    Birth Defects Res A Clin Mol Teratol; 2011 Jul; 91(7):603-9. PubMed ID: 21538817
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Inhibition or activation of Apert syndrome FGFR2 (S252W) signaling by specific glycosaminoglycans.
    McDowell LM; Frazier BA; Studelska DR; Giljum K; Chen J; Liu J; Yu K; Ornitz DM; Zhang L
    J Biol Chem; 2006 Mar; 281(11):6924-30. PubMed ID: 16373332
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 10.