217 related articles for article (PubMed ID: 23593521)
1. High content analysis of primary macrophages hosting proliferating Leishmania amastigotes: application to anti-leishmanial drug discovery.
Aulner N; Danckaert A; Rouault-Hardoin E; Desrivot J; Helynck O; Commere PH; Munier-Lehmann H; Späth GF; Shorte SL; Milon G; Prina E
PLoS Negl Trop Dis; 2013; 7(4):e2154. PubMed ID: 23593521
[TBL] [Abstract][Full Text] [Related]
2. A parasite rescue and transformation assay for antileishmanial screening against intracellular Leishmania donovani amastigotes in THP1 human acute monocytic leukemia cell line.
Jain SK; Sahu R; Walker LA; Tekwani BL
J Vis Exp; 2012 Dec; (70):. PubMed ID: 23299097
[TBL] [Abstract][Full Text] [Related]
3. A screen against Leishmania intracellular amastigotes: comparison to a promastigote screen and identification of a host cell-specific hit.
De Muylder G; Ang KK; Chen S; Arkin MR; Engel JC; McKerrow JH
PLoS Negl Trop Dis; 2011 Jul; 5(7):e1253. PubMed ID: 21811648
[TBL] [Abstract][Full Text] [Related]
4. Discovery of novel hit compounds with broad activity against visceral and cutaneous Leishmania species by comparative phenotypic screening.
Lamotte S; Aulner N; Späth GF; Prina E
Sci Rep; 2019 Jan; 9(1):438. PubMed ID: 30679614
[TBL] [Abstract][Full Text] [Related]
5. Development of NanoLuc-PEST expressing Leishmania mexicana as a new drug discovery tool for axenic- and intramacrophage-based assays.
Berry SL; Hameed H; Thomason A; Maciej-Hulme ML; Saif Abou-Akkada S; Horrocks P; Price HP
PLoS Negl Trop Dis; 2018 Jul; 12(7):e0006639. PubMed ID: 30001317
[TBL] [Abstract][Full Text] [Related]
6. From Drug Screening to Target Deconvolution: a Target-Based Drug Discovery Pipeline Using Leishmania Casein Kinase 1 Isoform 2 To Identify Compounds with Antileishmanial Activity.
Durieu E; Prina E; Leclercq O; Oumata N; Gaboriaud-Kolar N; Vougogiannopoulou K; Aulner N; Defontaine A; No JH; Ruchaud S; Skaltsounis AL; Galons H; Späth GF; Meijer L; Rachidi N
Antimicrob Agents Chemother; 2016 May; 60(5):2822-33. PubMed ID: 26902771
[TBL] [Abstract][Full Text] [Related]
7. In vitro leishmanicidal activity of monoterpenes present in two species of Protium (Burseraceae) on Leishmania amazonensis.
Santana RC; Rosa ADS; Mateus MHDS; Soares DC; Atella G; Guimarães AC; Siani AC; Ramos MFS; Saraiva EM; Pinto-da-Silva LH
J Ethnopharmacol; 2020 Sep; 259():112981. PubMed ID: 32442591
[TBL] [Abstract][Full Text] [Related]
8. Auranofin is an apoptosis-simulating agent with in vitro and in vivo anti-leishmanial activity.
Sharlow ER; Leimgruber S; Murray S; Lira A; Sciotti RJ; Hickman M; Hudson T; Leed S; Caridha D; Barrios AM; Close D; Grögl M; Lazo JS
ACS Chem Biol; 2014 Mar; 9(3):663-72. PubMed ID: 24328400
[TBL] [Abstract][Full Text] [Related]
9. A fluorometric method for evaluation of pharmacological activity against intracellular Leishmania amastigotes.
Bilbao-Ramos P; Sifontes-Rodríguez S; Dea-Ayuela MA; Bolás-Fernández F
J Microbiol Methods; 2012 Apr; 89(1):8-11. PubMed ID: 22310031
[TBL] [Abstract][Full Text] [Related]
10. Development of an automated image analysis protocol for quantification of intracellular forms of Leishmania spp.
Gomes-Alves AG; Maia AF; Cruz T; Castro H; Tomás AM
PLoS One; 2018; 13(8):e0201747. PubMed ID: 30071097
[TBL] [Abstract][Full Text] [Related]
11. Antileishmanial high-throughput drug screening reveals drug candidates with new scaffolds.
Siqueira-Neto JL; Song OR; Oh H; Sohn JH; Yang G; Nam J; Jang J; Cechetto J; Lee CB; Moon S; Genovesio A; Chatelain E; Christophe T; Freitas-Junior LH
PLoS Negl Trop Dis; 2010 May; 4(5):e675. PubMed ID: 20454559
[TBL] [Abstract][Full Text] [Related]
12. Intracellular parasite kill: flow cytometry and NO detection for rapid discrimination between anti-leishmanial activity and macrophage activation.
Kram D; Thäle C; Kolodziej H; Kiderlen AF
J Immunol Methods; 2008 Apr; 333(1-2):79-88. PubMed ID: 18313691
[TBL] [Abstract][Full Text] [Related]
13. Biogenesis of Leishmania-harbouring parasitophorous vacuoles following phagocytosis of the metacyclic promastigote or amastigote stages of the parasites.
Courret N; Fréhel C; Gouhier N; Pouchelet M; Prina E; Roux P; Antoine JC
J Cell Sci; 2002 Jun; 115(Pt 11):2303-16. PubMed ID: 12006615
[TBL] [Abstract][Full Text] [Related]
14. Bioluminescent Leishmania expressing luciferase for rapid and high throughput screening of drugs acting on amastigote-harbouring macrophages and for quantitative real-time monitoring of parasitism features in living mice.
Lang T; Goyard S; Lebastard M; Milon G
Cell Microbiol; 2005 Mar; 7(3):383-92. PubMed ID: 15679841
[TBL] [Abstract][Full Text] [Related]
15. A novel Leishmania major amastigote assay in 96-well format for rapid drug screening and its use for discovery and evaluation of a new class of leishmanicidal quinolinium salts.
Bringmann G; Thomale K; Bischof S; Schneider C; Schultheis M; Schwarz T; Moll H; Schurigt U
Antimicrob Agents Chemother; 2013 Jul; 57(7):3003-11. PubMed ID: 23587955
[TBL] [Abstract][Full Text] [Related]
16. Colorimetric assay for screening compounds against Leishmania amastigotes grown in macrophages.
Buckner FS; Wilson AJ
Am J Trop Med Hyg; 2005 May; 72(5):600-5. PubMed ID: 15891135
[TBL] [Abstract][Full Text] [Related]
17. 2-Amino-thiophene derivatives present antileishmanial activity mediated by apoptosis and immunomodulation in vitro.
Rodrigues KA; Dias CN; Néris PL; Rocha Jda C; Scotti MT; Scotti L; Mascarenhas SR; Veras RC; de Medeiros IA; Keesen Tde S; de Oliveira TB; de Lima Mdo C; Balliano TL; de Aquino TM; de Moura RO; Mendonça Junior FJ; de Oliveira MR
Eur J Med Chem; 2015 Dec; 106():1-14. PubMed ID: 26513640
[TBL] [Abstract][Full Text] [Related]
18. Simultaneous multi-parametric analysis of Leishmania and of its hosting mammal cells: A high content imaging-based method enabling sound drug discovery process.
Forestier CL; Späth GF; Prina E; Dasari S
Microb Pathog; 2015 Nov; 88():103-8. PubMed ID: 25448129
[TBL] [Abstract][Full Text] [Related]
19. An ex vivo multiparametric flow cytometry assay using human whole blood to simultaneously measure cytotoxicity and leishmanicidal activities.
Ribeiro JM; Bandeira CC; de Faria BG; Alves MLR; Vieira FO; Giunchetti RC; Uzonna JE; Teixeira-Carvalho A; Peruhype-Magalhães V; Souza-Fagundes EM
Exp Parasitol; 2020 Sep; 216():107940. PubMed ID: 32562606
[TBL] [Abstract][Full Text] [Related]
20. Effect of BMAP-28 antimicrobial peptides on Leishmania major promastigote and amastigote growth: role of leishmanolysin in parasite survival.
Lynn MA; Kindrachuk J; Marr AK; Jenssen H; Panté N; Elliott MR; Napper S; Hancock RE; McMaster WR
PLoS Negl Trop Dis; 2011; 5(5):e1141. PubMed ID: 21655347
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
