BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

338 related articles for article (PubMed ID: 23595760)

  • 1. MER5101, a novel Aβ1-15:DT conjugate vaccine, generates a robust anti-Aβ antibody response and attenuates Aβ pathology and cognitive deficits in APPswe/PS1ΔE9 transgenic mice.
    Liu B; Frost JL; Sun J; Fu H; Grimes S; Blackburn P; Lemere CA
    J Neurosci; 2013 Apr; 33(16):7027-37. PubMed ID: 23595760
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Short amyloid-beta (Abeta) immunogens reduce cerebral Abeta load and learning deficits in an Alzheimer's disease mouse model in the absence of an Abeta-specific cellular immune response.
    Maier M; Seabrook TJ; Lazo ND; Jiang L; Das P; Janus C; Lemere CA
    J Neurosci; 2006 May; 26(18):4717-28. PubMed ID: 16672644
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Soluble Aβ levels correlate with cognitive deficits in the 12-month-old APPswe/PS1dE9 mouse model of Alzheimer's disease.
    Zhang W; Hao J; Liu R; Zhang Z; Lei G; Su C; Miao J; Li Z
    Behav Brain Res; 2011 Sep; 222(2):342-50. PubMed ID: 21513747
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Vaccine efficacy of transcutaneous immunization with amyloid β using a dissolving microneedle array in a mouse model of Alzheimer's disease.
    Matsuo K; Okamoto H; Kawai Y; Quan YS; Kamiyama F; Hirobe S; Okada N; Nakagawa S
    J Neuroimmunol; 2014 Jan; 266(1-2):1-11. PubMed ID: 24315156
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Improving memory and decreasing cognitive impairment in Tg-APPswe/PSEN1dE9 mice with Aβ3-10 repeat fragment plasmid by reducing Aβ deposition and inflammatory response.
    Ma Y; Li Y; Zong LX; Xing XN; Zhang WG; Cao YP
    Brain Res; 2011 Jul; 1400():112-24. PubMed ID: 21658683
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Beta-amyloid deposition and functional impairment in the retina of the APPswe/PS1DeltaE9 transgenic mouse model of Alzheimer's disease.
    Perez SE; Lumayag S; Kovacs B; Mufson EJ; Xu S
    Invest Ophthalmol Vis Sci; 2009 Feb; 50(2):793-800. PubMed ID: 18791173
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Deletion of the type-1 interferon receptor in APPSWE/PS1ΔE9 mice preserves cognitive function and alters glial phenotype.
    Minter MR; Moore Z; Zhang M; Brody KM; Jones NC; Shultz SR; Taylor JM; Crack PJ
    Acta Neuropathol Commun; 2016 Jul; 4(1):72. PubMed ID: 27400725
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Voluntary Running Attenuates Memory Loss, Decreases Neuropathological Changes and Induces Neurogenesis in a Mouse Model of Alzheimer's Disease.
    Tapia-Rojas C; Aranguiz F; Varela-Nallar L; Inestrosa NC
    Brain Pathol; 2016 Jan; 26(1):62-74. PubMed ID: 25763997
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Passive immunization against pyroglutamate-3 amyloid-β reduces plaque burden in Alzheimer-like transgenic mice: a pilot study.
    Frost JL; Liu B; Kleinschmidt M; Schilling S; Demuth HU; Lemere CA
    Neurodegener Dis; 2012; 10(1-4):265-70. PubMed ID: 22343072
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Prophylactic Vaccine Based on Pyroglutamate-3 Amyloid β Generates Strong Antibody Response and Rescues Cognitive Decline in Alzheimer's Disease Model Mice.
    Li G; Hu ZW; Chen PG; Sun ZY; Chen YX; Zhao YF; Li YM
    ACS Chem Neurosci; 2017 Mar; 8(3):454-459. PubMed ID: 28292186
    [TBL] [Abstract][Full Text] [Related]  

  • 11. An attenuated immune response is sufficient to enhance cognition in an Alzheimer's disease mouse model immunized with amyloid-beta derivatives.
    Sigurdsson EM; Knudsen E; Asuni A; Fitzer-Attas C; Sage D; Quartermain D; Goni F; Frangione B; Wisniewski T
    J Neurosci; 2004 Jul; 24(28):6277-82. PubMed ID: 15254082
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Immunogenicity, efficacy, safety, and mechanism of action of epitope vaccine (Lu AF20513) for Alzheimer's disease: prelude to a clinical trial.
    Davtyan H; Ghochikyan A; Petrushina I; Hovakimyan A; Davtyan A; Poghosyan A; Marleau AM; Movsesyan N; Kiyatkin A; Rasool S; Larsen AK; Madsen PJ; Wegener KM; Ditlevsen DK; Cribbs DH; Pedersen LO; Agadjanyan MG
    J Neurosci; 2013 Mar; 33(11):4923-34. PubMed ID: 23486963
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Active Amyloid-β Vaccination Results in Epigenetic Changes in the Hippocampus of an Alzheimer's Disease-Like Mouse Model.
    Lardenoije R; van den Hove DLA; Jung SE; Havermans M; Blackburn P; Liu B; Rutten BPF; Lemere CA
    Curr Alzheimer Res; 2019; 16(9):861-870. PubMed ID: 31453788
    [TBL] [Abstract][Full Text] [Related]  

  • 14. An effector-reduced anti-β-amyloid (Aβ) antibody with unique aβ binding properties promotes neuroprotection and glial engulfment of Aβ.
    Adolfsson O; Pihlgren M; Toni N; Varisco Y; Buccarello AL; Antoniello K; Lohmann S; Piorkowska K; Gafner V; Atwal JK; Maloney J; Chen M; Gogineni A; Weimer RM; Mortensen DL; Friesenhahn M; Ho C; Paul R; Pfeifer A; Muhs A; Watts RJ
    J Neurosci; 2012 Jul; 32(28):9677-89. PubMed ID: 22787053
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Abeta42 gene vaccine prevents Abeta42 deposition in brain of double transgenic mice.
    Qu BX; Xiang Q; Li L; Johnston SA; Hynan LS; Rosenberg RN
    J Neurol Sci; 2007 Sep; 260(1-2):204-13. PubMed ID: 17574274
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Novel Abeta immunogens: is shorter better?
    Lemere CA; Maier M; Peng Y; Jiang L; Seabrook TJ
    Curr Alzheimer Res; 2007 Sep; 4(4):427-36. PubMed ID: 17908047
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Immunotherapy to improve cognition and reduce pathological species in an Alzheimer's disease mouse model.
    Herline K; Prelli F; Mehta P; MacMurray C; Goñi F; Wisniewski T
    Alzheimers Res Ther; 2018 Jun; 10(1):54. PubMed ID: 29914551
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Efficacy of Chronic Paroxetine Treatment in Mitigating Amyloid Pathology and Microgliosis in APPSWE/PS1ΔE9 Transgenic Mice.
    Sivasaravanaparan M; Olesen LØ; Severino M; von Linstow CU; Lambertsen KL; Gramsbergen JB; Hasselstrøm J; Metaxas A; Wiborg O; Finsen B
    J Alzheimers Dis; 2022; 87(2):685-699. PubMed ID: 35342093
    [TBL] [Abstract][Full Text] [Related]  

  • 19. S14G-humanin improves cognitive deficits and reduces amyloid pathology in the middle-aged APPswe/PS1dE9 mice.
    Zhang W; Zhang W; Li Z; Hao J; Zhang Z; Liu L; Mao N; Miao J; Zhang L
    Pharmacol Biochem Behav; 2012 Jan; 100(3):361-9. PubMed ID: 21993310
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Dendrimeric Abeta1-15 is an effective immunogen in wildtype and APP-tg mice.
    Seabrook TJ; Thomas K; Jiang L; Bloom J; Spooner E; Maier M; Bitan G; Lemere CA
    Neurobiol Aging; 2007 Jun; 28(6):813-23. PubMed ID: 16725229
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 17.