BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

195 related articles for article (PubMed ID: 23595767)

  • 1. Protein sorting motifs in the cytoplasmic tail of SorCS1 control generation of Alzheimer's amyloid-β peptide.
    Lane RF; Steele JW; Cai D; Ehrlich ME; Attie AD; Gandy S
    J Neurosci; 2013 Apr; 33(16):7099-107. PubMed ID: 23595767
    [TBL] [Abstract][Full Text] [Related]  

  • 2. SorCS1 variants and amyloid precursor protein (APP) are co-transported in neurons but only SorCS1c modulates anterograde APP transport.
    Hermey G; Schmidt N; Bluhm B; Mensching D; Ostermann K; Rupp C; Kuhl D; Kins S
    J Neurochem; 2015 Oct; 135(1):60-75. PubMed ID: 26119586
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Diabetes-associated SorCS1 regulates Alzheimer's amyloid-beta metabolism: evidence for involvement of SorL1 and the retromer complex.
    Lane RF; Raines SM; Steele JW; Ehrlich ME; Lah JA; Small SA; Tanzi RE; Attie AD; Gandy S
    J Neurosci; 2010 Sep; 30(39):13110-5. PubMed ID: 20881129
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Huntingtin associated protein 1 regulates trafficking of the amyloid precursor protein and modulates amyloid beta levels in neurons.
    Yang GZ; Yang M; Lim Y; Lu JJ; Wang TH; Qi JG; Zhong JH; Zhou XF
    J Neurochem; 2012 Sep; 122(5):1010-22. PubMed ID: 22731248
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Intracellular amyloid precursor protein sorting and amyloid-β secretion are regulated by Src-mediated phosphorylation of Mint2.
    Chaufty J; Sullivan SE; Ho A
    J Neurosci; 2012 Jul; 32(28):9613-25. PubMed ID: 22787047
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Differential regulation of amyloid precursor protein sorting with pathological mutations results in a distinct effect on amyloid-β production.
    Lin YC; Wang JY; Wang KC; Liao JY; Cheng IH
    J Neurochem; 2014 Nov; 131(4):407-12. PubMed ID: 25053581
    [TBL] [Abstract][Full Text] [Related]  

  • 7. SORCS1 alters amyloid precursor protein processing and variants may increase Alzheimer's disease risk.
    Reitz C; Tokuhiro S; Clark LN; Conrad C; Vonsattel JP; Hazrati LN; Palotás A; Lantigua R; Medrano M; Z Jiménez-Velázquez I; Vardarajan B; Simkin I; Haines JL; Pericak-Vance MA; Farrer LA; Lee JH; Rogaeva E; George-Hyslop PS; Mayeux R
    Ann Neurol; 2011 Jan; 69(1):47-64. PubMed ID: 21280075
    [TBL] [Abstract][Full Text] [Related]  

  • 8. BACE1 retrograde trafficking is uniquely regulated by the cytoplasmic domain of sortilin.
    Finan GM; Okada H; Kim TW
    J Biol Chem; 2011 Apr; 286(14):12602-16. PubMed ID: 21245145
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Retromer binds the FANSHY sorting motif in SorLA to regulate amyloid precursor protein sorting and processing.
    Fjorback AW; Seaman M; Gustafsen C; Mehmedbasic A; Gokool S; Wu C; Militz D; Schmidt V; Madsen P; Nyengaard JR; Willnow TE; Christensen EI; Mobley WB; Nykjær A; Andersen OM
    J Neurosci; 2012 Jan; 32(4):1467-80. PubMed ID: 22279231
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Cross-linking of cell surface amyloid precursor protein leads to increased β-amyloid peptide production in hippocampal neurons: implications for Alzheimer's disease.
    Lefort R; Pozueta J; Shelanski M
    J Neurosci; 2012 Aug; 32(31):10674-85. PubMed ID: 22855816
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Distinct Functions for Anterograde and Retrograde Sorting of SORLA in Amyloidogenic Processes in the Brain.
    Dumanis SB; Burgert T; Caglayan S; Füchtbauer A; Füchtbauer EM; Schmidt V; Willnow TE
    J Neurosci; 2015 Sep; 35(37):12703-13. PubMed ID: 26377460
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Amyloid precursor protein (APP) traffics from the cell surface via endosomes for amyloid β (Aβ) production in the trans-Golgi network.
    Choy RW; Cheng Z; Schekman R
    Proc Natl Acad Sci U S A; 2012 Jul; 109(30):E2077-82. PubMed ID: 22711829
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Unexpected partial correction of metabolic and behavioral phenotypes of Alzheimer's APP/PSEN1 mice by gene targeting of diabetes/Alzheimer's-related Sorcs1.
    Knight EM; Ruiz HH; Kim SH; Harte JC; Hsieh W; Glabe C; Klein WL; Attie AD; Buettner C; Ehrlich ME; Gandy S
    Acta Neuropathol Commun; 2016 Feb; 4():16. PubMed ID: 26916443
    [TBL] [Abstract][Full Text] [Related]  

  • 14. SNX27 and SORLA Interact to Reduce Amyloidogenic Subcellular Distribution and Processing of Amyloid Precursor Protein.
    Huang TY; Zhao Y; Li X; Wang X; Tseng IC; Thompson R; Tu S; Willnow TE; Zhang YW; Xu H
    J Neurosci; 2016 Jul; 36(30):7996-8011. PubMed ID: 27466343
    [TBL] [Abstract][Full Text] [Related]  

  • 15. GGA1-mediated endocytic traffic of LR11/SorLA alters APP intracellular distribution and amyloid-β production.
    Herskowitz JH; Offe K; Deshpande A; Kahn RA; Levey AI; Lah JJ
    Mol Biol Cell; 2012 Jul; 23(14):2645-57. PubMed ID: 22621900
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Trafficking in Alzheimer's Disease: Modulation of APP Transport and Processing by the Transmembrane Proteins LRP1, SorLA, SorCS1c, Sortilin, and Calsyntenin.
    Eggert S; Thomas C; Kins S; Hermey G
    Mol Neurobiol; 2018 Jul; 55(7):5809-5829. PubMed ID: 29079999
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Retrieval of the Alzheimer's amyloid precursor protein from the endosome to the TGN is S655 phosphorylation state-dependent and retromer-mediated.
    Vieira SI; Rebelo S; Esselmann H; Wiltfang J; Lah J; Lane R; Small SA; Gandy S; da Cruz E Silva EF; da Cruz E Silva OA
    Mol Neurodegener; 2010 Oct; 5():40. PubMed ID: 20937087
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Engulfment adapter PTB domain containing 1 interacts with and affects processing of the amyloid-β precursor protein.
    Beyer AS; von Einem B; Schwanzar D; Keller IE; Hellrung A; Thal DR; Ingelsson M; Makarova A; Deng M; Chhabra ES; Pröpper C; Böckers TM; Hyman BT; von Arnim CA
    Neurobiol Aging; 2012 Apr; 33(4):732-43. PubMed ID: 20674096
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Adaptor protein sorting nexin 17 regulates amyloid precursor protein trafficking and processing in the early endosomes.
    Lee J; Retamal C; Cuitiño L; Caruano-Yzermans A; Shin JE; van Kerkhof P; Marzolo MP; Bu G
    J Biol Chem; 2008 Apr; 283(17):11501-8. PubMed ID: 18276590
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The ubiquitin ligase UBE4B regulates amyloid precursor protein ubiquitination, endosomal trafficking, and amyloid β42 generation and secretion.
    Gireud-Goss M; Reyes S; Tewari R; Patrizz A; Howe MD; Kofler J; Waxham MN; McCullough LD; Bean AJ
    Mol Cell Neurosci; 2020 Oct; 108():103542. PubMed ID: 32841720
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.