BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

208 related articles for article (PubMed ID: 23601319)

  • 1. Cooperative heparin-mediated oligomerization of fibroblast growth factor-1 (FGF1) precedes recruitment of FGFR2 to ternary complexes.
    Brown A; Robinson CJ; Gallagher JT; Blundell TL
    Biophys J; 2013 Apr; 104(8):1720-30. PubMed ID: 23601319
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Cooperative dimerization of fibroblast growth factor 1 (FGF1) upon a single heparin saccharide may drive the formation of 2:2:1 FGF1.FGFR2c.heparin ternary complexes.
    Robinson CJ; Harmer NJ; Goodger SJ; Blundell TL; Gallagher JT
    J Biol Chem; 2005 Dec; 280(51):42274-82. PubMed ID: 16219767
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Influence of heparin mimetics on assembly of the FGF.FGFR4 signaling complex.
    Saxena K; Schieborr U; Anderka O; Duchardt-Ferner E; Elshorst B; Gande SL; Janzon J; Kudlinzki D; Sreeramulu S; Dreyer MK; Wendt KU; Herbert C; Duchaussoy P; Bianciotto M; Driguez PA; Lassalle G; Savi P; Mohammadi M; Bono F; Schwalbe H
    J Biol Chem; 2010 Aug; 285(34):26628-40. PubMed ID: 20547770
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Heparin modulates the mitogenic activity of fibroblast growth factor by inducing dimerization of its receptor. a 3D view by using NMR.
    Nieto L; Canales Á; Fernández IS; Santillana E; González-Corrochano R; Redondo-Horcajo M; Cañada FJ; Nieto P; Martín-Lomas M; Giménez-Gallego G; Jiménez-Barbero J
    Chembiochem; 2013 Sep; 14(14):1732-44. PubMed ID: 23940086
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Crystal structure of fibroblast growth factor receptor ectodomain bound to ligand and heparin.
    Pellegrini L; Burke DF; von Delft F; Mulloy B; Blundell TL
    Nature; 2000 Oct; 407(6807):1029-34. PubMed ID: 11069186
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Differential effects of heparin saccharides on the formation of specific fibroblast growth factor (FGF) and FGF receptor complexes.
    Ostrovsky O; Berman B; Gallagher J; Mulloy B; Fernig DG; Delehedde M; Ron D
    J Biol Chem; 2002 Jan; 277(4):2444-53. PubMed ID: 11714710
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Gas-Phase Analysis of the Complex of Fibroblast GrowthFactor 1 with Heparan Sulfate: A Traveling Wave Ion Mobility Spectrometry (TWIMS) and Molecular Modeling Study.
    Zhao Y; Singh A; Xu Y; Zong C; Zhang F; Boons GJ; Liu J; Linhardt RJ; Woods RJ; Amster IJ
    J Am Soc Mass Spectrom; 2017 Jan; 28(1):96-109. PubMed ID: 27663556
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Compositional analysis of heparin/heparan sulfate interacting with fibroblast growth factor.fibroblast growth factor receptor complexes.
    Zhang F; Zhang Z; Lin X; Beenken A; Eliseenkova AV; Mohammadi M; Linhardt RJ
    Biochemistry; 2009 Sep; 48(35):8379-86. PubMed ID: 19591432
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Multimers of the fibroblast growth factor (FGF)-FGF receptor-saccharide complex are formed on long oligomers of heparin.
    Harmer NJ; Robinson CJ; Adam LE; Ilag LL; Robinson CV; Gallagher JT; Blundell TL
    Biochem J; 2006 Feb; 393(Pt 3):741-8. PubMed ID: 16223363
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Analysis of the fibroblast growth factor receptor (FGFR) signalling network with heparin as coreceptor: evidence for the expansion of the core FGFR signalling network.
    Xu R; Rudd TR; Hughes AJ; Siligardi G; Fernig DG; Yates EA
    FEBS J; 2013 May; 280(10):2260-70. PubMed ID: 23441759
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Kinetic model for FGF, FGFR, and proteoglycan signal transduction complex assembly.
    Ibrahimi OA; Zhang F; Hrstka SC; Mohammadi M; Linhardt RJ
    Biochemistry; 2004 Apr; 43(16):4724-30. PubMed ID: 15096041
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Interaction of fibroblast growth factor-1 and related peptides with heparan sulfate and its oligosaccharides.
    Fromm JR; Hileman RE; Weiler JM; Linhardt RJ
    Arch Biochem Biophys; 1997 Oct; 346(2):252-62. PubMed ID: 9343372
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Heparin/Heparan sulfate domains in binding and signaling of fibroblast growth factor 8b.
    Loo BM; Salmivirta M
    J Biol Chem; 2002 Sep; 277(36):32616-23. PubMed ID: 12077148
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Control of fibroblast growth factor (FGF) 7- and FGF1-induced mitogenesis and downstream signaling by distinct heparin octasaccharide motifs.
    Luo Y; Ye S; Kan M; McKeehan WL
    J Biol Chem; 2006 Jul; 281(30):21052-21061. PubMed ID: 16728399
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Fibroblast growth factor receptors 1 and 2 interact differently with heparin/heparan sulfate. Implications for dynamic assembly of a ternary signaling complex.
    Powell AK; Fernig DG; Turnbull JE
    J Biol Chem; 2002 Aug; 277(32):28554-63. PubMed ID: 12034712
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Sequence analyses and comparative modeling of fly and worm fibroblast growth factor receptors indicate that the determinants for FGF and heparin binding are retained in evolution.
    Nagendra HG; Harrington AE; Harmer NJ; Pellegrini L; Blundell TL; Burke DF
    FEBS Lett; 2001 Jul; 501(1):51-8. PubMed ID: 11457455
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Common and specific determinants for fibroblast growth factors in the ectodomain of the receptor kinase complex.
    Wang F; Lu W; McKeehan K; Mohamedali K; Gabriel JL; Kan M; McKeehan WL
    Biochemistry; 1999 Jan; 38(1):160-71. PubMed ID: 9890894
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Similarities and differences between the effects of heparin and glypican-1 on the bioactivity of acidic fibroblast growth factor and the keratinocyte growth factor.
    Berman B; Ostrovsky O; Shlissel M; Lang T; Regan D; Vlodavsky I; Ishai-Michaeli R; Ron D
    J Biol Chem; 1999 Dec; 274(51):36132-8. PubMed ID: 10593896
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Requirement for anticoagulant heparan sulfate in the fibroblast growth factor receptor complex.
    McKeehan WL; Wu X; Kan M
    J Biol Chem; 1999 Jul; 274(31):21511-4. PubMed ID: 10419453
    [TBL] [Abstract][Full Text] [Related]  

  • 20. A dimeric ternary complex of FGFR [correction of FGFR1], heparin and FGF-1 leads to an 'electrostatic sandwich' model for heparin binding.
    Huhtala MT; Pentikäinen OT; Johnson MS
    Structure; 1999 Jun; 7(6):699-709. PubMed ID: 10404599
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.