BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

97 related articles for article (PubMed ID: 23602399)

  • 1. Tri-substituted imidazole analogues of SB203580 as inducers for cardiomyogenesis of human embryonic stem cells.
    Low JL; Jürjens G; Seayad J; Seow J; Ting S; Laco F; Reuveny S; Oh S; Chai CL
    Bioorg Med Chem Lett; 2013 Jun; 23(11):3300-3. PubMed ID: 23602399
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Role of the hydrogen bonding heteroatom-Lys53 interaction between the p38alpha mitogen-activated protein (MAP) kinase and pyridinyl-substituted 5-membered heterocyclic ring inhibitors.
    Abu Thaher B; Koch P; Schattel V; Laufer S
    J Med Chem; 2009 Apr; 52(8):2613-7. PubMed ID: 19301816
    [TBL] [Abstract][Full Text] [Related]  

  • 3. p38 Mitogen-activated protein kinase controls a switch between cardiomyocyte and neuronal commitment of murine embryonic stem cells by activating myocyte enhancer factor 2C-dependent bone morphogenetic protein 2 transcription.
    Wu J; Kubota J; Hirayama J; Nagai Y; Nishina S; Yokoi T; Asaoka Y; Seo J; Shimizu N; Kajiho H; Watanabe T; Azuma N; Katada T; Nishina H
    Stem Cells Dev; 2010 Nov; 19(11):1723-34. PubMed ID: 20412016
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Distinct regulation of mitogen-activated protein kinase activities is coupled with enhanced cardiac differentiation of human embryonic stem cells.
    Kempf H; Lecina M; Ting S; Zweigerdt R; Oh S
    Stem Cell Res; 2011 Nov; 7(3):198-209. PubMed ID: 21907163
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Tetra-substituted pyridinylimidazoles as dual inhibitors of p38α mitogen-activated protein kinase and c-Jun N-terminal kinase 3 for potential treatment of neurodegenerative diseases.
    Muth F; Günther M; Bauer SM; Döring E; Fischer S; Maier J; Drückes P; Köppler J; Trappe J; Rothbauer U; Koch P; Laufer SA
    J Med Chem; 2015 Jan; 58(1):443-56. PubMed ID: 25475894
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Fluorescence polarization binding assay to develop inhibitors of inactive p38alpha mitogen-activated protein kinase.
    Munoz L; Selig R; Yeung YT; Peifer C; Hauser D; Laufer S
    Anal Biochem; 2010 Jun; 401(1):125-33. PubMed ID: 20175985
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Chemically defined medium supporting cardiomyocyte differentiation of human embryonic stem cells.
    Xu XQ; Graichen R; Soo SY; Balakrishnan T; Rahmat SN; Sieh S; Tham SC; Freund C; Moore J; Mummery C; Colman A; Zweigerdt R; Davidson BP
    Differentiation; 2008 Nov; 76(9):958-70. PubMed ID: 18557764
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Enhanced cardiomyogenesis of human embryonic stem cells by a small molecular inhibitor of p38 MAPK.
    Graichen R; Xu X; Braam SR; Balakrishnan T; Norfiza S; Sieh S; Soo SY; Tham SC; Mummery C; Colman A; Zweigerdt R; Davidson BP
    Differentiation; 2008 Apr; 76(4):357-70. PubMed ID: 18021257
    [TBL] [Abstract][Full Text] [Related]  

  • 9. p38 mitogen activated protein kinase controls two successive-steps during the early mesodermal commitment of embryonic stem cells.
    Barruet E; Hadadeh O; Peiretti F; Renault VM; Hadjal Y; Bernot D; Tournaire R; Negre D; Juhan-Vague I; Alessi MC; Binétruy B
    Stem Cells Dev; 2011 Jul; 20(7):1233-46. PubMed ID: 20954847
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Cardiomyocyte differentiation of pluripotent stem cells with SB203580 analogues correlates with Wnt pathway CK1 inhibition independent of p38 MAPK signaling.
    Laco F; Low JL; Seow J; Woo TL; Zhong Q; Seayad J; Liu Z; Wei H; Reuveny S; Elliott DA; Chai CL; Oh SK
    J Mol Cell Cardiol; 2015 Mar; 80():56-70. PubMed ID: 25528965
    [TBL] [Abstract][Full Text] [Related]  

  • 11. p38alpha MAP kinase-deficient mouse embryonic stem cells can differentiate to endothelial cells, smooth muscle cells, and neurons.
    Guo YL; Ye J; Huang F
    Dev Dyn; 2007 Dec; 236(12):3383-92. PubMed ID: 17994546
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Icariin promotes expression of PGC-1alpha, PPARalpha, and NRF-1 during cardiomyocyte differentiation of murine embryonic stem cells in vitro.
    Ding L; Liang XG; Zhu DY; Lou YJ
    Acta Pharmacol Sin; 2007 Oct; 28(10):1541-9. PubMed ID: 17883938
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Dynamics in the p38alpha MAP kinase-SB203580 complex observed by liquid-state NMR spectroscopy.
    Honndorf VS; Coudevylle N; Laufer S; Becker S; Griesinger C
    Angew Chem Int Ed Engl; 2008; 47(19):3548-51. PubMed ID: 18389508
    [No Abstract]   [Full Text] [Related]  

  • 14. Pharmacophore design of p38α MAP kinase inhibitors with either 2,4,5-trisubstituted or 1,2,4,5-tetrasubstituted imidazole scaffold.
    Scior T; Domeyer DM; Cuanalo-Contreras K; Laufer SA
    Curr Med Chem; 2011; 18(10):1526-39. PubMed ID: 21428890
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Bcl2, a transcriptional target of p38alpha, is critical for neuronal commitment of mouse embryonic stem cells.
    Trouillas M; Saucourt C; Duval D; Gauthereau X; Thibault C; Dembele D; Feraud O; Menager J; Rallu M; Pradier L; Boeuf H
    Cell Death Differ; 2008 Sep; 15(9):1450-9. PubMed ID: 18437159
    [TBL] [Abstract][Full Text] [Related]  

  • 16. p38α MAPK inhibition translates to cell cycle re-entry of neonatal rat ventricular cardiomyocytes and de novo nestin expression in response to thrombin and after apex resection.
    Hertig V; Brezai A; Bergeron A; Villeneuve L; Gillis MA; Calderone A
    Sci Rep; 2019 Jun; 9(1):8203. PubMed ID: 31160695
    [TBL] [Abstract][Full Text] [Related]  

  • 17. p38 mitogen-activated protein kinase activity commits embryonic stem cells to either neurogenesis or cardiomyogenesis.
    Aouadi M; Bost F; Caron L; Laurent K; Le Marchand Brustel Y; Binétruy B
    Stem Cells; 2006 May; 24(5):1399-406. PubMed ID: 16424397
    [TBL] [Abstract][Full Text] [Related]  

  • 18. An optimized and versatile synthesis to pyridinylimidazole-type p38α mitogen activated protein kinase inhibitors.
    El-Gokha A; Laufer SA; Koch P
    Org Biomol Chem; 2015 Nov; 13(43):10699-704. PubMed ID: 26351018
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Decisive role of water and protein dynamics in residence time of p38α MAP kinase inhibitors.
    Pantsar T; Kaiser PD; Kudolo M; Forster M; Rothbauer U; Laufer SA
    Nat Commun; 2022 Jan; 13(1):569. PubMed ID: 35091547
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Mitogen-activated protein kinase in endothelin-1-induced cardiac differentiation of mouse embryonic stem cells.
    Chen M; Lin YQ; Xie SL; Wang JF
    J Cell Biochem; 2010 Dec; 111(6):1619-28. PubMed ID: 21053276
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 5.