164 related articles for article (PubMed ID: 23604979)
1. Extra-hepatic cancer represses hepatic drug metabolism via interleukin (IL)-6 signalling.
Kacevska M; Mahns A; Sharma R; Clarke SJ; Robertson GR; Liddle C
Pharm Res; 2013 Sep; 30(9):2270-8. PubMed ID: 23604979
[TBL] [Abstract][Full Text] [Related]
2. Transcriptional repression of hepatic cytochrome P450 3A4 gene in the presence of cancer.
Charles KA; Rivory LP; Brown SL; Liddle C; Clarke SJ; Robertson GR
Clin Cancer Res; 2006 Dec; 12(24):7492-7. PubMed ID: 17189422
[TBL] [Abstract][Full Text] [Related]
3. Downregulation of drug transport and metabolism in mice bearing extra-hepatic malignancies.
Sharma R; Kacevska M; London R; Clarke SJ; Liddle C; Robertson G
Br J Cancer; 2008 Jan; 98(1):91-7. PubMed ID: 18059400
[TBL] [Abstract][Full Text] [Related]
4. Extrahepatic cancer suppresses nuclear receptor-regulated drug metabolism.
Kacevska M; Downes MR; Sharma R; Evans RM; Clarke SJ; Liddle C; Robertson GR
Clin Cancer Res; 2011 May; 17(10):3170-80. PubMed ID: 21498392
[TBL] [Abstract][Full Text] [Related]
5. Role of hepatic cytochromes P450 in bioactivation of the anticancer drug ellipticine: studies with the hepatic NADPH:cytochrome P450 reductase null mouse.
Stiborová M; Arlt VM; Henderson CJ; Wolf CR; Kotrbová V; Moserová M; Hudecek J; Phillips DH; Frei E
Toxicol Appl Pharmacol; 2008 Feb; 226(3):318-27. PubMed ID: 17976674
[TBL] [Abstract][Full Text] [Related]
6. Liver membrane proteome glycosylation changes in mice bearing an extra-hepatic tumor.
Lee A; Chick JM; Kolarich D; Haynes PA; Robertson GR; Tsoli M; Jankova L; Clarke SJ; Packer NH; Baker MS
Mol Cell Proteomics; 2011 Sep; 10(9):M900538MCP200. PubMed ID: 20167946
[TBL] [Abstract][Full Text] [Related]
7. Experimental cancer cachexia: the role of host-derived cytokines interleukin (IL)-6, IL-12, interferon-gamma, and tumor necrosis factor alpha evaluated in gene knockout, tumor-bearing mice on C57 Bl background and eicosanoid-dependent cachexia.
Cahlin C; Körner A; Axelsson H; Wang W; Lundholm K; Svanberg E
Cancer Res; 2000 Oct; 60(19):5488-93. PubMed ID: 11034092
[TBL] [Abstract][Full Text] [Related]
8. Inflammation and altered drug clearance in cancer: transcriptional repression of a human CYP3A4 transgene in tumor-bearing mice.
Robertson GR; Liddle C; Clarke SJ
Clin Pharmacol Ther; 2008 Jun; 83(6):894-7. PubMed ID: 18388870
[TBL] [Abstract][Full Text] [Related]
9. Effects of interleukin-6 (IL-6) and an anti-IL-6 monoclonal antibody on drug-metabolizing enzymes in human hepatocyte culture.
Dickmann LJ; Patel SK; Rock DA; Wienkers LC; Slatter JG
Drug Metab Dispos; 2011 Aug; 39(8):1415-22. PubMed ID: 21555507
[TBL] [Abstract][Full Text] [Related]
10. In vivo antitumor activity and host toxicity of methoxymorpholinyl doxorubicin: role of cytochrome P450 3A.
Quintieri L; Rosato A; Napoli E; Sola F; Geroni C; Floreani M; Zanovello P
Cancer Res; 2000 Jun; 60(12):3232-8. PubMed ID: 10866316
[TBL] [Abstract][Full Text] [Related]
11. Midazolam metabolism in cytochrome P450 3A knockout mice can be attributed to up-regulated CYP2C enzymes.
van Waterschoot RA; van Herwaarden AE; Lagas JS; Sparidans RW; Wagenaar E; van der Kruijssen CM; Goldstein JA; Zeldin DC; Beijnen JH; Schinkel AH
Mol Pharmacol; 2008 Mar; 73(3):1029-36. PubMed ID: 18156313
[TBL] [Abstract][Full Text] [Related]
12. Inhibition and stimulation of intestinal and hepatic CYP3A activity: studies in humanized CYP3A4 transgenic mice using triazolam.
van Waterschoot RA; Rooswinkel RW; Sparidans RW; van Herwaarden AE; Beijnen JH; Schinkel AH
Drug Metab Dispos; 2009 Dec; 37(12):2305-13. PubMed ID: 19752211
[TBL] [Abstract][Full Text] [Related]
13. Antitumor effect of alpha-galactosylceramide (KRN7000) on spontaneous hepatic metastases requires endogenous interleukin 12 in the liver.
Fuji N; Ueda Y; Fujiwara H; Toh T; Yoshimura T; Yamagishi H
Clin Cancer Res; 2000 Aug; 6(8):3380-7. PubMed ID: 10955826
[TBL] [Abstract][Full Text] [Related]
14. Comparison of the hepatic metabolism of triazolam in wild-type andCyp3a-knockout mice for understanding CYP3A-mediated metabolism inCYP3A-humanised mice
Minegishi G; Kazuki Y; Yamasaki Y; Okuya F; Akita H; Oshimura M; Kobayashi K
Xenobiotica; 2019 Nov; 49(11):1303-1310. PubMed ID: 30561249
[TBL] [Abstract][Full Text] [Related]
15. Disrupted hepatic pentose phosphate pathway directly participates in and indirectly promotes CYP3A reduction: A new strategy for CYP3A-mediated drug hepatotoxicity.
Liu J; Jin X; Zhou F; Chen H; Wang W; Liu Y; Wang G; Hao K; Zhang J
Br J Pharmacol; 2020 Apr; 177(7):1538-1555. PubMed ID: 31670839
[TBL] [Abstract][Full Text] [Related]
16. Cytochrome P450 and antioxidant activity in interleukin-6 knockout mice after induction of the acute-phase response.
Warren GW; van Ess PJ; Watson AM; Mattson MP; Blouin RA
J Interferon Cytokine Res; 2001 Oct; 21(10):821-6. PubMed ID: 11710994
[TBL] [Abstract][Full Text] [Related]
17. Downregulation of mouse hepatic CYP3A protein by 3-methylcholanthrene does not require cytochrome P450-dependent metabolism.
Lee C; Ding X; Riddick DS
Drug Metab Dispos; 2013 Oct; 41(10):1782-6. PubMed ID: 23846873
[TBL] [Abstract][Full Text] [Related]
18. Murine Cyp3a knockout chimeric mice with humanized liver: prediction of the metabolic profile of nefazodone in humans.
Nakada N; Kawamura A; Kamimura H; Sato K; Kazuki Y; Kakuni M; Ohbuchi M; Kato K; Tateno C; Oshimura M; Usui T
Biopharm Drug Dispos; 2016 Jan; 37(1):3-14. PubMed ID: 26352195
[TBL] [Abstract][Full Text] [Related]
19. Fasting-Induced Changes in Hepatic P450 Mediated Drug Metabolism Are Largely Independent of the Constitutive Androstane Receptor CAR.
de Vries EM; Lammers LA; Achterbergh R; Klümpen HJ; Mathot RA; Boelen A; Romijn JA
PLoS One; 2016; 11(7):e0159552. PubMed ID: 27434302
[TBL] [Abstract][Full Text] [Related]
20. Induction via Functional Protein Stabilization of Hepatic Cytochromes P450 upon gp78/Autocrine Motility Factor Receptor (AMFR) Ubiquitin E3-Ligase Genetic Ablation in Mice: Therapeutic and Toxicological Relevance.
Kwon D; Kim SM; Jacob P; Liu Y; Correia MA
Mol Pharmacol; 2019 Nov; 96(5):641-654. PubMed ID: 31492698
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
