BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

205 related articles for article (PubMed ID: 23609448)

  • 1. Mycobacterium tuberculosis maltosyltransferase GlgE, a genetically validated antituberculosis target, is negatively regulated by Ser/Thr phosphorylation.
    Leiba J; Syson K; Baronian G; Zanella-Cléon I; Kalscheuer R; Kremer L; Bornemann S; Molle V
    J Biol Chem; 2013 Jun; 288(23):16546-16556. PubMed ID: 23609448
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Ligand-bound Structures and Site-directed Mutagenesis Identify the Acceptor and Secondary Binding Sites of Streptomyces coelicolor Maltosyltransferase GlgE.
    Syson K; Stevenson CE; Miah F; Barclay JE; Tang M; Gorelik A; Rashid AM; Lawson DM; Bornemann S
    J Biol Chem; 2016 Oct; 291(41):21531-21540. PubMed ID: 27531751
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Structure of Streptomyces maltosyltransferase GlgE, a homologue of a genetically validated anti-tuberculosis target.
    Syson K; Stevenson CEM; Rejzek M; Fairhurst SA; Nair A; Bruton CJ; Field RA; Chater KF; Lawson DM; Bornemann S
    J Biol Chem; 2011 Nov; 286(44):38298-38310. PubMed ID: 21914799
    [TBL] [Abstract][Full Text] [Related]  

  • 4. A temperature-sensitive Mycobacterium smegmatis glgE mutation leads to a loss of GlgE enzyme activity and thermostability and the accumulation of α-maltose-1-phosphate.
    Syson K; Batey SFD; Schindler S; Kalscheuer R; Bornemann S
    Biochim Biophys Acta Gen Subj; 2021 Feb; 1865(2):129783. PubMed ID: 33166604
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Inhibition of the DevSR Two-Component System by Overexpression of Mycobacterium tuberculosis PknB in Mycobacterium smegmatis.
    Bae HJ; Lee HN; Baek MN; Park EJ; Eom CY; Ko IJ; Kang HY; Oh JI
    Mol Cells; 2017 Sep; 40(9):632-642. PubMed ID: 28843272
    [TBL] [Abstract][Full Text] [Related]  

  • 6. α-Glucan biosynthesis and the GlgE pathway in Mycobacterium tuberculosis.
    Bornemann S
    Biochem Soc Trans; 2016 Feb; 44(1):68-73. PubMed ID: 26862190
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Phosphorylation of the Mycobacterium tuberculosis beta-ketoacyl-acyl carrier protein reductase MabA regulates mycolic acid biosynthesis.
    Veyron-Churlet R; Zanella-Cléon I; Cohen-Gonsaud M; Molle V; Kremer L
    J Biol Chem; 2010 Apr; 285(17):12714-25. PubMed ID: 20178986
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Structure of Mycobacterium thermoresistibile GlgE defines novel conformational states that contribute to the catalytic mechanism.
    Mendes V; Blaszczyk M; Maranha A; Empadinhas N; Blundell TL
    Sci Rep; 2015 Nov; 5():17144. PubMed ID: 26616850
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Self-poisoning of Mycobacterium tuberculosis by targeting GlgE in an alpha-glucan pathway.
    Kalscheuer R; Syson K; Veeraraghavan U; Weinrick B; Biermann KE; Liu Z; Sacchettini JC; Besra G; Bornemann S; Jacobs WR
    Nat Chem Biol; 2010 May; 6(5):376-84. PubMed ID: 20305657
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Structural insight into how Streptomyces coelicolor maltosyl transferase GlgE binds α-maltose 1-phosphate and forms a maltosyl-enzyme intermediate.
    Syson K; Stevenson CE; Rashid AM; Saalbach G; Tang M; Tuukkanen A; Svergun DI; Withers SG; Lawson DM; Bornemann S
    Biochemistry; 2014 Apr; 53(15):2494-504. PubMed ID: 24689960
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Multisystem Analysis of
    Carette X; Platig J; Young DC; Helmel M; Young AT; Wang Z; Potluri LP; Moody CS; Zeng J; Prisic S; Paulson JN; Muntel J; Madduri AVR; Velarde J; Mayfield JA; Locher C; Wang T; Quackenbush J; Rhee KY; Moody DB; Steen H; Husson RN
    mBio; 2018 Mar; 9(2):. PubMed ID: 29511081
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The Ser/Thr protein kinase PknB is essential for sustaining mycobacterial growth.
    Fernandez P; Saint-Joanis B; Barilone N; Jackson M; Gicquel B; Cole ST; Alzari PM
    J Bacteriol; 2006 Nov; 188(22):7778-84. PubMed ID: 16980473
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Expression and characterization of the Mycobacterium tuberculosis serine/threonine protein kinase PknB.
    Av-Gay Y; Jamil S; Drews SJ
    Infect Immun; 1999 Nov; 67(11):5676-82. PubMed ID: 10531215
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Unexpected and widespread connections between bacterial glycogen and trehalose metabolism.
    Chandra G; Chater KF; Bornemann S
    Microbiology (Reading); 2011 Jun; 157(Pt 6):1565-1572. PubMed ID: 21474533
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Phosphorylation of Mycobacterium tuberculosis Ser/Thr phosphatase by PknA and PknB.
    Sajid A; Arora G; Gupta M; Upadhyay S; Nandicoori VK; Singh Y
    PLoS One; 2011 Mar; 6(3):e17871. PubMed ID: 21423706
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Synthesis of a C-phosphonate mimic of maltose-1-phosphate and inhibition studies on Mycobacterium tuberculosis GlgE.
    Veleti SK; Lindenberger JJ; Ronning DR; Sucheck SJ
    Bioorg Med Chem; 2014 Feb; 22(4):1404-11. PubMed ID: 24461562
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Crystal structures of Mycobacterium tuberculosis GlgE and complexes with non-covalent inhibitors.
    Lindenberger JJ; Veleti SK; Wilson BN; Sucheck SJ; Ronning DR
    Sci Rep; 2015 Aug; 5():12830. PubMed ID: 26245983
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Dual control of RegX3 transcriptional activity by SenX3 and PknB.
    Park EJ; Kwon YM; Lee JW; Kang HY; Oh JI
    J Biol Chem; 2019 Jul; 294(28):11023-11034. PubMed ID: 31160336
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Synthesis of a poly-hydroxypyrolidine-based inhibitor of Mycobacterium tuberculosis GlgE.
    Veleti SK; Lindenberger JJ; Thanna S; Ronning DR; Sucheck SJ
    J Org Chem; 2014 Oct; 79(20):9444-50. PubMed ID: 25137149
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Protein kinases PknA and PknB independently and coordinately regulate essential Mycobacterium tuberculosis physiologies and antimicrobial susceptibility.
    Zeng J; Platig J; Cheng TY; Ahmed S; Skaf Y; Potluri LP; Schwartz D; Steen H; Moody DB; Husson RN
    PLoS Pathog; 2020 Apr; 16(4):e1008452. PubMed ID: 32255801
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.