BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

303 related articles for article (PubMed ID: 23620596)

  • 1. Substrate-modulated cytochrome P450 17A1 and cytochrome b5 interactions revealed by NMR.
    Estrada DF; Laurence JS; Scott EE
    J Biol Chem; 2013 Jun; 288(23):17008-17018. PubMed ID: 23620596
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Kinetic processivity of the two-step oxidations of progesterone and pregnenolone to androgens by human cytochrome P450 17A1.
    Gonzalez E; Guengerich FP
    J Biol Chem; 2017 Aug; 292(32):13168-13185. PubMed ID: 28684414
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Human cytochrome P450 17A1 conformational selection: modulation by ligand and cytochrome b5.
    Estrada DF; Skinner AL; Laurence JS; Scott EE
    J Biol Chem; 2014 May; 289(20):14310-20. PubMed ID: 24671419
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Cytochrome b5 Activates the 17,20-Lyase Activity of Human Cytochrome P450 17A1 by Increasing the Coupling of NADPH Consumption to Androgen Production.
    Peng HM; Im SC; Pearl NM; Turcu AF; Rege J; Waskell L; Auchus RJ
    Biochemistry; 2016 Aug; 55(31):4356-65. PubMed ID: 27426448
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Catalytically relevant electrostatic interactions of cytochrome P450c17 (CYP17A1) and cytochrome b5.
    Peng HM; Liu J; Forsberg SE; Tran HT; Anderson SM; Auchus RJ
    J Biol Chem; 2014 Dec; 289(49):33838-49. PubMed ID: 25315771
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Cytochrome P450 17A1 Interactions with the FMN Domain of Its Reductase as Characterized by NMR.
    Estrada DF; Laurence JS; Scott EE
    J Biol Chem; 2016 Feb; 291(8):3990-4003. PubMed ID: 26719338
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Role of cytochrome b5 in the modulation of the enzymatic activities of cytochrome P450 17α-hydroxylase/17,20-lyase (P450 17A1).
    Bhatt MR; Khatri Y; Rodgers RJ; Martin LL
    J Steroid Biochem Mol Biol; 2017 Jun; 170():2-18. PubMed ID: 26976652
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Proteomics, modeling, and fluorescence assays delineate cytochrome b
    Tateishi Y; Webb SN; Li B; Liu L; Lindsey Rose K; Leser M; Patel P; Guengerich FP
    J Biol Chem; 2024 Mar; 300(3):105688. PubMed ID: 38280431
    [TBL] [Abstract][Full Text] [Related]  

  • 9. A Homodimer Model Can Resolve the Conundrum as to How Cytochrome P450 Oxidoreductase and Cytochrome b5 Compete for the Same Binding Site on Cytochrome P450c17.
    Holien JK; Parker MW; Conley AJ; Corbin CJ; Rodgers RJ; Martin LL
    Curr Protein Pept Sci; 2017; 18(5):515-521. PubMed ID: 28000554
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Evidence that cytochrome b5 acts as a redox donor in CYP17A1 mediated androgen synthesis.
    Duggal R; Liu Y; Gregory MC; Denisov IG; Kincaid JR; Sligar SG
    Biochem Biophys Res Commun; 2016 Aug; 477(2):202-8. PubMed ID: 27297105
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Structures of human steroidogenic cytochrome P450 17A1 with substrates.
    Petrunak EM; DeVore NM; Porubsky PR; Scott EE
    J Biol Chem; 2014 Nov; 289(47):32952-64. PubMed ID: 25301938
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Effect of mutations in porcine CYB5A and CYP17A1 on the metabolism of pregnenolone.
    Squires EJ; Gray MA; Lou Y
    J Steroid Biochem Mol Biol; 2019 Dec; 195():105469. PubMed ID: 31509771
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Tight binding of cytochrome b
    Kim D; Kim V; McCarty KD; Guengerich FP
    J Biol Chem; 2021; 296():100571. PubMed ID: 33753170
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Structural insights into the function of steroidogenic cytochrome P450 17A1.
    Yadav R; Petrunak EM; Estrada DF; Scott EE
    Mol Cell Endocrinol; 2017 Feb; 441():68-75. PubMed ID: 27566228
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Hydroxylation and lyase reactions of steroids catalyzed by mouse cytochrome P450 17A1 (Cyp17a1).
    Lee SG; Kim V; Lee GH; Kim C; Jeong E; Guengerich FP; Kim D
    J Inorg Biochem; 2023 Mar; 240():112085. PubMed ID: 36640554
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Substrate-Specific Allosteric Effects on the Enhancement of CYP17A1 Lyase Efficiency by Cytochrome
    Liu Y; Denisov IG; Sligar SG; Kincaid JR
    J Am Chem Soc; 2021 Mar; 143(10):3729-3733. PubMed ID: 33656879
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Mechanistic Scrutiny Identifies a Kinetic Role for Cytochrome b5 Regulation of Human Cytochrome P450c17 (CYP17A1, P450 17A1).
    Simonov AN; Holien JK; Yeung JC; Nguyen AD; Corbin CJ; Zheng J; Kuznetsov VL; Auchus RJ; Conley AJ; Bond AM; Parker MW; Rodgers RJ; Martin LL
    PLoS One; 2015; 10(11):e0141252. PubMed ID: 26587646
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Conformational selection dominates binding of steroids to human cytochrome P450 17A1.
    Guengerich FP; Wilkey CJ; Glass SM; Reddish MJ
    J Biol Chem; 2019 Jun; 294(26):10028-10041. PubMed ID: 31072872
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Cytochrome b
    Duggal R; Denisov IG; Sligar SG
    FEBS Lett; 2018 Jul; 592(13):2282-2288. PubMed ID: 29888793
    [TBL] [Abstract][Full Text] [Related]  

  • 20. P450c17 mutations R347H and R358Q selectively disrupt 17,20-lyase activity by disrupting interactions with P450 oxidoreductase and cytochrome b5.
    Geller DH; Auchus RJ; Miller WL
    Mol Endocrinol; 1999 Jan; 13(1):167-75. PubMed ID: 9892022
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 16.