These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
115 related articles for article (PubMed ID: 23624267)
1. Synthesis and evaluation of a new phosphorylated ribavirin prodrug. Dong SD; Lin CC; Schroeder M Antiviral Res; 2013 Jul; 99(1):18-26. PubMed ID: 23624267 [TBL] [Abstract][Full Text] [Related]
2. Phosphorodiamidates as a promising new phosphate prodrug motif for antiviral drug discovery: application to anti-HCV agents. McGuigan C; Madela K; Aljarah M; Bourdin C; Arrica M; Barrett E; Jones S; Kolykhalov A; Bleiman B; Bryant KD; Ganguly B; Gorovits E; Henson G; Hunley D; Hutchins J; Muhammad J; Obikhod A; Patti J; Walters CR; Wang J; Vernachio J; Ramamurty CV; Battina SK; Chamberlain S J Med Chem; 2011 Dec; 54(24):8632-45. PubMed ID: 22039920 [TBL] [Abstract][Full Text] [Related]
3. Taribavirin in the treatment of hepatitis C. Deming P; Arora S Expert Opin Investig Drugs; 2011 Oct; 20(10):1435-43. PubMed ID: 21854301 [TBL] [Abstract][Full Text] [Related]
4. Highly active macromolecular prodrugs inhibit expression of the hepatitis C virus genome in the host cells. Ruiz-Sanchis P; Wohl BM; Smith AA; Zuwala K; Melchjorsen J; Tolstrup M; Zelikin AN Adv Healthc Mater; 2015 Jan; 4(1):65-8. PubMed ID: 25132665 [TBL] [Abstract][Full Text] [Related]
5. Liver-targeted prodrugs of 2'-C-methyladenosine for therapy of hepatitis C virus infection. Hecker SJ; Reddy KR; van Poelje PD; Sun Z; Huang W; Varkhedkar V; Reddy MV; Fujitaki JM; Olsen DB; Koeplinger KA; Boyer SH; Linemeyer DL; MacCoss M; Erion MD J Med Chem; 2007 Aug; 50(16):3891-6. PubMed ID: 17636948 [TBL] [Abstract][Full Text] [Related]
6. Synthesis and Evaluation of Bile Acid-Ribavirin Conjugates as Prodrugs to Target the Liver. Dong Z; Li Q; Guo D; Shu Y; Polli JE J Pharm Sci; 2015 Sep; 104(9):2864-76. PubMed ID: 25645375 [TBL] [Abstract][Full Text] [Related]
7. Ascending multiple-dose pharmacokinetics of viramidine, a prodrug of ribavirin, in adult subjects with compensated hepatitis C infection. Aora S; Xu C; Teng A; Peterson J; Yeh LT; Gish R; Lau D; Rossi S; Lin CC J Clin Pharmacol; 2005 Mar; 45(3):275-85. PubMed ID: 15703363 [TBL] [Abstract][Full Text] [Related]
8. Pharmacokinetics and safety of viramidine, a prodrug of ribavirin, in healthy volunteers. Lin CC; Philips L; Xu C; Yeh LT J Clin Pharmacol; 2004 Mar; 44(3):265-75. PubMed ID: 14973309 [TBL] [Abstract][Full Text] [Related]
9. Viramidine, a prodrug of ribavirin, shows better liver-targeting properties and safety profiles than ribavirin in animals. Lin CC; Yeh LT; Vitarella D; Hong Z Antivir Chem Chemother; 2003 May; 14(3):145-52. PubMed ID: 14521331 [TBL] [Abstract][Full Text] [Related]
10. Dual-action mechanism of viramidine functioning as a prodrug and as a catabolic inhibitor for ribavirin. Wu JZ; Larson G; Hong Z Antimicrob Agents Chemother; 2004 Oct; 48(10):4006-8. PubMed ID: 15388466 [TBL] [Abstract][Full Text] [Related]
11. Macromolecular (pro)drugs with concurrent direct activity against the hepatitis C virus and inflammation. Wohl BM; Smith AA; Jensen BE; Zelikin AN J Control Release; 2014 Dec; 196():197-207. PubMed ID: 25451544 [TBL] [Abstract][Full Text] [Related]
12. Antiviral efficacy upon administration of a HepDirect prodrug of 2'-C-methylcytidine to hepatitis C virus-infected chimpanzees. Carroll SS; Koeplinger K; Vavrek M; Zhang NR; Handt L; MacCoss M; Olsen DB; Reddy KR; Sun Z; van Poelje PD; Fujitaki JM; Boyer SH; Linemeyer DL; Hecker SJ; Erion MD Antimicrob Agents Chemother; 2011 Aug; 55(8):3854-60. PubMed ID: 21628542 [TBL] [Abstract][Full Text] [Related]
13. Application of the phosphoramidate ProTide approach to the antiviral drug ribavirin. Derudas M; Brancale A; Naesens L; Neyts J; Balzarini J; McGuigan C Bioorg Med Chem; 2010 Apr; 18(7):2748-55. PubMed ID: 20207546 [TBL] [Abstract][Full Text] [Related]
14. Narrow therapeutic window of ribavirin as an inhibitor of nitric oxide synthesis is broadened by macromolecular prodrugs. Wohl BM; Smith AA; Kryger MB; Zelikin AN Biomacromolecules; 2013 Nov; 14(11):3916-26. PubMed ID: 24156371 [TBL] [Abstract][Full Text] [Related]
15. Synthesis and biological evaluation of pyrimidine nucleoside monophosphate prodrugs targeted against influenza virus. Meneghesso S; Vanderlinden E; Stevaert A; McGuigan C; Balzarini J; Naesens L Antiviral Res; 2012 Apr; 94(1):35-43. PubMed ID: 22306172 [TBL] [Abstract][Full Text] [Related]
16. Cyclic phosphoramidates as prodrugs of 2'-C-methylcytidine. Meppen M; Pacini B; Bazzo R; Koch U; Leone JF; Koeplinger KA; Rowley M; Altamura S; Di Marco A; Fiore F; Giuliano C; Gonzalez-Paz O; Laufer R; Pucci V; Narjes F; Gardelli C Eur J Med Chem; 2009 Sep; 44(9):3765-70. PubMed ID: 19493593 [TBL] [Abstract][Full Text] [Related]
17. β-D-2'-α-F-2'-β-C-Methyl-6-O-substituted 3',5'-cyclic phosphate nucleotide prodrugs as inhibitors of hepatitis C virus replication: a structure-activity relationship study. Du J; Bao D; Chun BK; Jiang Y; Reddy PG; Zhang HR; Ross BS; Bansal S; Bao H; Espiritu C; Lam AM; Murakami E; Niu C; Micolochick Steuer HM; Furman PA; Otto MJ; Sofia MJ Bioorg Med Chem Lett; 2012 Sep; 22(18):5924-9. PubMed ID: 22892115 [TBL] [Abstract][Full Text] [Related]
18. Macromolecular prodrugs of ribavirin combat side effects and toxicity with no loss of activity of the drug. Kryger MB; Wohl BM; Smith AA; Zelikin AN Chem Commun (Camb); 2013 Apr; 49(26):2643-5. PubMed ID: 23431562 [TBL] [Abstract][Full Text] [Related]