Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

475 related articles for article (PubMed ID: 23624914)

  • 1. ERK and AKT signaling cooperate to translationally regulate survivin expression for metastatic progression of colorectal cancer.
    Ye Q; Cai W; Zheng Y; Evers BM; She QB
    Oncogene; 2014 Apr; 33(14):1828-39. PubMed ID: 23624914
    [TBL] [Abstract][Full Text] [Related]  

  • 2. AKT inhibition overcomes rapamycin resistance by enhancing the repressive function of PRAS40 on mTORC1/4E-BP1 axis.
    Mi W; Ye Q; Liu S; She QB
    Oncotarget; 2015 Jun; 6(16):13962-77. PubMed ID: 25961827
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Growth-factor dependent expression of the translationally controlled tumour protein TCTP is regulated through the PI3-K/Akt/mTORC1 signalling pathway.
    Bommer UA; Iadevaia V; Chen J; Knoch B; Engel M; Proud CG
    Cell Signal; 2015 Aug; 27(8):1557-68. PubMed ID: 25936523
    [TBL] [Abstract][Full Text] [Related]  

  • 4. 4EBP1/eIF4E and p70S6K/RPS6 axes play critical and distinct roles in hepatocarcinogenesis driven by AKT and N-Ras proto-oncogenes in mice.
    Wang C; Cigliano A; Jiang L; Li X; Fan B; Pilo MG; Liu Y; Gui B; Sini M; Smith JW; Dombrowski F; Calvisi DF; Evert M; Chen X
    Hepatology; 2015 Jan; 61(1):200-13. PubMed ID: 25145583
    [TBL] [Abstract][Full Text] [Related]  

  • 5. 4E-BP1 is a key effector of the oncogenic activation of the AKT and ERK signaling pathways that integrates their function in tumors.
    She QB; Halilovic E; Ye Q; Zhen W; Shirasawa S; Sasazuki T; Solit DB; Rosen N
    Cancer Cell; 2010 Jul; 18(1):39-51. PubMed ID: 20609351
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Feedback loops blockade potentiates apoptosis induction and antitumor activity of a novel AKT inhibitor DC120 in human liver cancer.
    Yang F; Deng R; Qian XJ; Chang SH; Wu XQ; Qin J; Feng GK; Ding K; Zhu XF
    Cell Death Dis; 2014 Mar; 5(3):e1114. PubMed ID: 24625973
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Ran is a potential therapeutic target for cancer cells with molecular changes associated with activation of the PI3K/Akt/mTORC1 and Ras/MEK/ERK pathways.
    Yuen HF; Chan KK; Grills C; Murray JT; Platt-Higgins A; Eldin OS; O'Byrne K; Janne P; Fennell DA; Johnston PG; Rudland PS; El-Tanani M
    Clin Cancer Res; 2012 Jan; 18(2):380-91. PubMed ID: 22090358
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The synergistic inhibition of breast cancer proliferation by combined treatment with 4EGI-1 and MK2206.
    Wang H; Huang F; Wang J; Wang P; Lv W; Hong L; Li S; Zhou J
    Cell Cycle; 2015; 14(2):232-42. PubMed ID: 25607647
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Signal pathways involved in activation of p70S6K and phosphorylation of 4E-BP1 following exposure of multiple myeloma tumor cells to interleukin-6.
    Shi Y; Hsu JH; Hu L; Gera J; Lichtenstein A
    J Biol Chem; 2002 May; 277(18):15712-20. PubMed ID: 11872747
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The PP242 mammalian target of rapamycin (mTOR) inhibitor activates extracellular signal-regulated kinase (ERK) in multiple myeloma cells via a target of rapamycin complex 1 (TORC1)/eukaryotic translation initiation factor 4E (eIF-4E)/RAF pathway and activation is a mechanism of resistance.
    Hoang B; Benavides A; Shi Y; Yang Y; Frost P; Gera J; Lichtenstein A
    J Biol Chem; 2012 Jun; 287(26):21796-805. PubMed ID: 22556409
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Rapamycin attenuates BAFF-extended proliferation and survival via disruption of mTORC1/2 signaling in normal and neoplastic B-lymphoid cells.
    Zeng Q; Qin S; Zhang H; Liu B; Qin J; Wang X; Zhang R; Liu C; Dong X; Zhang S; Huang S; Chen L
    J Cell Physiol; 2018 Jan; 233(1):516-529. PubMed ID: 28300280
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Phosphatidylinositol-3 kinase-dependent translational regulation of Id1 involves the PPM1G phosphatase.
    Xu K; Wang L; Feng W; Feng Y; Shu HK
    Oncogene; 2016 Nov; 35(44):5807-5816. PubMed ID: 27065332
    [TBL] [Abstract][Full Text] [Related]  

  • 13. 4E-BP1, a multifactor regulated multifunctional protein.
    Qin X; Jiang B; Zhang Y
    Cell Cycle; 2016; 15(6):781-6. PubMed ID: 26901143
    [TBL] [Abstract][Full Text] [Related]  

  • 14. S6K1 and 4E-BP1 are independent regulated and control cellular growth in bladder cancer.
    Nawroth R; Stellwagen F; Schulz WA; Stoehr R; Hartmann A; Krause BJ; Gschwend JE; Retz M
    PLoS One; 2011; 6(11):e27509. PubMed ID: 22110663
    [TBL] [Abstract][Full Text] [Related]  

  • 15. New insights into 4E-BP1-regulated translation in cancer progression and metastasis.
    Wang J; Ye Q; She QB
    Cancer Cell Microenviron; 2014; 1(5):. PubMed ID: 26005705
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Constitutive phosphorylation of the mTORC2/Akt/4E-BP1 pathway in newly derived canine hemangiosarcoma cell lines.
    Murai A; Asa SA; Kodama A; Hirata A; Yanai T; Sakai H
    BMC Vet Res; 2012 Jul; 8():128. PubMed ID: 22839755
    [TBL] [Abstract][Full Text] [Related]  

  • 17. eIF4E knockdown decreases breast cancer cell growth without activating Akt signaling.
    Soni A; Akcakanat A; Singh G; Luyimbazi D; Zheng Y; Kim D; Gonzalez-Angulo A; Meric-Bernstam F
    Mol Cancer Ther; 2008 Jul; 7(7):1782-8. PubMed ID: 18644990
    [TBL] [Abstract][Full Text] [Related]  

  • 18. mTORC1 drives HIF-1α and VEGF-A signalling via multiple mechanisms involving 4E-BP1, S6K1 and STAT3.
    Dodd KM; Yang J; Shen MH; Sampson JR; Tee AR
    Oncogene; 2015 Apr; 34(17):2239-50. PubMed ID: 24931163
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Both mTORC1 and mTORC2 are involved in the regulation of cell adhesion.
    Chen L; Xu B; Liu L; Liu C; Luo Y; Chen X; Barzegar M; Chung J; Huang S
    Oncotarget; 2015 Mar; 6(9):7136-50. PubMed ID: 25762619
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Inhibition of mammalian target of rapamycin induces phosphatidylinositol 3-kinase-dependent and Mnk-mediated eukaryotic translation initiation factor 4E phosphorylation.
    Wang X; Yue P; Chan CB; Ye K; Ueda T; Watanabe-Fukunaga R; Fukunaga R; Fu H; Khuri FR; Sun SY
    Mol Cell Biol; 2007 Nov; 27(21):7405-13. PubMed ID: 17724079
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 24.