316 related articles for article (PubMed ID: 23630944)
1. A novel function of Ataxin-1 in the modulation of PP2A activity is dysregulated in the spinocerebellar ataxia type 1.
Sánchez I; Piñol P; Corral-Juan M; Pandolfo M; Matilla-Dueñas A
Hum Mol Genet; 2013 Sep; 22(17):3425-37. PubMed ID: 23630944
[TBL] [Abstract][Full Text] [Related]
2. Ataxin-1 regulates the cerebellar bioenergetics proteome through the GSK3β-mTOR pathway which is altered in Spinocerebellar ataxia type 1 (SCA1).
Sánchez I; Balagué E; Matilla-Dueñas A
Hum Mol Genet; 2016 Sep; 25(18):4021-4040. PubMed ID: 27466200
[TBL] [Abstract][Full Text] [Related]
3. Dopamine D2 receptor signaling modulates mutant ataxin-1 S776 phosphorylation and aggregation.
Hearst SM; Lopez ME; Shao Q; Liu Y; Vig PJ
J Neurochem; 2010 Aug; 114(3):706-16. PubMed ID: 20477910
[TBL] [Abstract][Full Text] [Related]
4. Beyond the glutamine expansion: influence of posttranslational modifications of ataxin-1 in the pathogenesis of spinocerebellar ataxia type 1.
Ju H; Kokubu H; Lim J
Mol Neurobiol; 2014 Dec; 50(3):866-874. PubMed ID: 24752589
[TBL] [Abstract][Full Text] [Related]
5. Partial loss of ataxin-1 function contributes to transcriptional dysregulation in spinocerebellar ataxia type 1 pathogenesis.
Crespo-Barreto J; Fryer JD; Shaw CA; Orr HT; Zoghbi HY
PLoS Genet; 2010 Jul; 6(7):e1001021. PubMed ID: 20628574
[TBL] [Abstract][Full Text] [Related]
6. Lithium therapy improves neurological function and hippocampal dendritic arborization in a spinocerebellar ataxia type 1 mouse model.
Watase K; Gatchel JR; Sun Y; Emamian E; Atkinson R; Richman R; Mizusawa H; Orr HT; Shaw C; Zoghbi HY
PLoS Med; 2007 May; 4(5):e182. PubMed ID: 17535104
[TBL] [Abstract][Full Text] [Related]
7. Down-regulation of the dopamine receptor D2 in mice lacking ataxin 1.
Goold R; Hubank M; Hunt A; Holton J; Menon RP; Revesz T; Pandolfo M; Matilla-Dueñas A
Hum Mol Genet; 2007 Sep; 16(17):2122-34. PubMed ID: 17599952
[TBL] [Abstract][Full Text] [Related]
8. Progress in pathogenesis studies of spinocerebellar ataxia type 1.
Cummings CJ; Orr HT; Zoghbi HY
Philos Trans R Soc Lond B Biol Sci; 1999 Jun; 354(1386):1079-81. PubMed ID: 10434309
[TBL] [Abstract][Full Text] [Related]
9. SCA1-phosphorylation, a regulator of Ataxin-1 function and pathogenesis.
Orr HT
Prog Neurobiol; 2012 Dec; 99(3):179-85. PubMed ID: 22531670
[TBL] [Abstract][Full Text] [Related]
10. Glial S100B protein modulates mutant ataxin-1 aggregation and toxicity: TRTK12 peptide, a potential candidate for SCA1 therapy.
Vig PJ; Hearst S; Shao Q; Lopez ME; Murphy HA; Safaya E
Cerebellum; 2011 Jun; 10(2):254-66. PubMed ID: 21384195
[TBL] [Abstract][Full Text] [Related]
11. USP7, a ubiquitin-specific protease, interacts with ataxin-1, the SCA1 gene product.
Hong S; Kim SJ; Ka S; Choi I; Kang S
Mol Cell Neurosci; 2002 Jun; 20(2):298-306. PubMed ID: 12093161
[TBL] [Abstract][Full Text] [Related]
12. Pathogenic mechanisms of a polyglutamine-mediated neurodegenerative disease, spinocerebellar ataxia type 1.
Zoghbi HY; Orr HT
J Biol Chem; 2009 Mar; 284(12):7425-9. PubMed ID: 18957430
[TBL] [Abstract][Full Text] [Related]
13. Focused cerebellar laser light induced hyperthermia improves symptoms and pathology of polyglutamine disease SCA1 in a mouse model.
Hearst SM; Shao Q; Lopez M; Raucher D; Vig PJ
Cerebellum; 2014 Oct; 13(5):596-606. PubMed ID: 24930030
[TBL] [Abstract][Full Text] [Related]
14. Hsp70/Hsc70 regulates the effect phosphorylation has on stabilizing ataxin-1.
Jorgensen ND; Andresen JM; Pitt JE; Swenson MA; Zoghbi HY; Orr HT
J Neurochem; 2007 Sep; 102(6):2040-2048. PubMed ID: 17540008
[TBL] [Abstract][Full Text] [Related]
15. Opposing effects of polyglutamine expansion on native protein complexes contribute to SCA1.
Lim J; Crespo-Barreto J; Jafar-Nejad P; Bowman AB; Richman R; Hill DE; Orr HT; Zoghbi HY
Nature; 2008 Apr; 452(7188):713-8. PubMed ID: 18337722
[TBL] [Abstract][Full Text] [Related]
16. Suppression of calbindin-D28k expression exacerbates SCA1 phenotype in a disease mouse model.
Vig PJ; Wei J; Shao Q; Lopez ME; Halperin R; Gerber J
Cerebellum; 2012 Sep; 11(3):718-32. PubMed ID: 22076800
[TBL] [Abstract][Full Text] [Related]
17. An out-of-frame overlapping reading frame in the ataxin-1 coding sequence encodes a novel ataxin-1 interacting protein.
Bergeron D; Lapointe C; Bissonnette C; Tremblay G; Motard J; Roucou X
J Biol Chem; 2013 Jul; 288(30):21824-35. PubMed ID: 23760502
[TBL] [Abstract][Full Text] [Related]
18. 14-3-3 Binding to ataxin-1(ATXN1) regulates its dephosphorylation at Ser-776 and transport to the nucleus.
Lai S; O'Callaghan B; Zoghbi HY; Orr HT
J Biol Chem; 2011 Oct; 286(40):34606-16. PubMed ID: 21835928
[TBL] [Abstract][Full Text] [Related]
19. The spinocerebellar ataxia type 1 protein, ataxin-1, has RNA-binding activity that is inversely affected by the length of its polyglutamine tract.
Yue S; Serra HG; Zoghbi HY; Orr HT
Hum Mol Genet; 2001 Jan; 10(1):25-30. PubMed ID: 11136710
[TBL] [Abstract][Full Text] [Related]
20. Partial loss of Tip60 slows mid-stage neurodegeneration in a spinocerebellar ataxia type 1 (SCA1) mouse model.
Gehrking KM; Andresen JM; Duvick L; Lough J; Zoghbi HY; Orr HT
Hum Mol Genet; 2011 Jun; 20(11):2204-12. PubMed ID: 21427130
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]