BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

266 related articles for article (PubMed ID: 23631427)

  • 1. Dual targeting of adenosine A(2A) receptors and monoamine oxidase B by 4H-3,1-benzothiazin-4-ones.
    Stössel A; Schlenk M; Hinz S; Küppers P; Heer J; Gütschow M; Müller CE
    J Med Chem; 2013 Jun; 56(11):4580-96. PubMed ID: 23631427
    [TBL] [Abstract][Full Text] [Related]  

  • 2. 8-Substituted 1,3-dimethyltetrahydropyrazino[2,1-f]purinediones: Water-soluble adenosine receptor antagonists and monoamine oxidase B inhibitors.
    Brunschweiger A; Koch P; Schlenk M; Rafehi M; Radjainia H; Küppers P; Hinz S; Pineda F; Wiese M; Hockemeyer J; Heer J; Denonne F; Müller CE
    Bioorg Med Chem; 2016 Nov; 24(21):5462-5480. PubMed ID: 27658798
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Novel multi-target directed ligands based on annelated xanthine scaffold with aromatic substituents acting on adenosine receptor and monoamine oxidase B. Synthesis, in vitro and in silico studies.
    Załuski M; Schabikowski J; Schlenk M; Olejarz-Maciej A; Kubas B; Karcz T; Kuder K; Latacz G; Zygmunt M; Synak D; Hinz S; Müller CE; Kieć-Kononowicz K
    Bioorg Med Chem; 2019 Apr; 27(7):1195-1210. PubMed ID: 30808606
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Dual inhibition of monoamine oxidase B and antagonism of the adenosine A(2A) receptor by (E,E)-8-(4-phenylbutadien-1-yl)caffeine analogues.
    Pretorius J; Malan SF; Castagnoli N; Bergh JJ; Petzer JP
    Bioorg Med Chem; 2008 Sep; 16(18):8676-84. PubMed ID: 18723354
    [TBL] [Abstract][Full Text] [Related]  

  • 5. 1,3-Dialkyl-substituted tetrahydropyrimido[1,2-f]purine-2,4-diones as multiple target drugs for the potential treatment of neurodegenerative diseases.
    Koch P; Akkari R; Brunschweiger A; Borrmann T; Schlenk M; Küppers P; Köse M; Radjainia H; Hockemeyer J; Drabczyńska A; Kieć-Kononowicz K; Müller CE
    Bioorg Med Chem; 2013 Dec; 21(23):7435-52. PubMed ID: 24139167
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Benzothiazinones: a novel class of adenosine receptor antagonists structurally unrelated to xanthine and adenine derivatives.
    Gütschow M; Schlenk M; Gäb J; Paskaleva M; Alnouri MW; Scolari S; Iqbal J; Müller CE
    J Med Chem; 2012 Apr; 55(7):3331-41. PubMed ID: 22409573
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Chemoinformatics Profiling of the Chromone Nucleus as a MAO-B/A2AAR Dual Binding Scaffold.
    Cruz-Monteagudo M; Borges F; Cordeiro MNDS; Helguera AM; Tejera E; Paz-Y-Mino C; Sanchez-Rodriguez A; Perera-Sardina Y; Perez-Castillo Y
    Curr Neuropharmacol; 2017 Nov; 15(8):1117-1135. PubMed ID: 28093976
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Inhibition of monoamine oxidase B by analogues of the adenosine A2A receptor antagonist (E)-8-(3-chlorostyryl)caffeine (CSC).
    Vlok N; Malan SF; Castagnoli N; Bergh JJ; Petzer JP
    Bioorg Med Chem; 2006 May; 14(10):3512-21. PubMed ID: 16442801
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The inhibition of monoamine oxidase by 2H-1,4-benzothiazin-3(4H)-ones.
    Hitge R; Petzer JP; Petzer A
    Bioorg Med Chem Lett; 2022 Dec; 77():129038. PubMed ID: 36307034
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The adenosine receptor affinities and monoamine oxidase B inhibitory properties of sulfanylphthalimide analogues.
    Van der Walt MM; Terre'Blanche G; Petzer A; Petzer JP
    Bioorg Chem; 2015 Apr; 59():117-23. PubMed ID: 25746740
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Novel reversible monoamine oxidase A inhibitors: highly potent and selective 3-(1H-pyrrol-3-yl)-2-oxazolidinones.
    Valente S; Tomassi S; Tempera G; Saccoccio S; Agostinelli E; Mai A
    J Med Chem; 2011 Dec; 54(23):8228-32. PubMed ID: 22017497
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Discovery of a novel class of potent coumarin monoamine oxidase B inhibitors: development and biopharmacological profiling of 7-[(3-chlorobenzyl)oxy]-4-[(methylamino)methyl]-2H-chromen-2-one methanesulfonate (NW-1772) as a highly potent, selective, reversible, and orally active monoamine oxidase B inhibitor.
    Pisani L; Muncipinto G; Miscioscia TF; Nicolotti O; Leonetti F; Catto M; Caccia C; Salvati P; Soto-Otero R; Mendez-Alvarez E; Passeleu C; Carotti A
    J Med Chem; 2009 Nov; 52(21):6685-706. PubMed ID: 19810674
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Discovery, biological evaluation, and structure-activity and -selectivity relationships of 6'-substituted (E)-2-(benzofuran-3(2H)-ylidene)-N-methylacetamides, a novel class of potent and selective monoamine oxidase inhibitors.
    Pisani L; Barletta M; Soto-Otero R; Nicolotti O; Mendez-Alvarez E; Catto M; Introcaso A; Stefanachi A; Cellamare S; Altomare C; Carotti A
    J Med Chem; 2013 Mar; 56(6):2651-64. PubMed ID: 23437843
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The adenosine A(2A) antagonistic properties of selected C8-substituted xanthines.
    Van der Walt MM; Terre'Blanche G; Petzer A; Lourens AC; Petzer JP
    Bioorg Chem; 2013 Aug; 49():49-58. PubMed ID: 23892098
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Indazole- and indole-5-carboxamides: selective and reversible monoamine oxidase B inhibitors with subnanomolar potency.
    Tzvetkov NT; Hinz S; Küppers P; Gastreich M; Müller CE
    J Med Chem; 2014 Aug; 57(15):6679-703. PubMed ID: 24955776
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Rasagiline [N-propargyl-1R(+)-aminoindan], a selective and potent inhibitor of mitochondrial monoamine oxidase B.
    Youdim MB; Gross A; Finberg JP
    Br J Pharmacol; 2001 Jan; 132(2):500-6. PubMed ID: 11159700
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Novel, Dual Target-Directed Annelated Xanthine Derivatives Acting on Adenosine Receptors and Monoamine Oxidase B.
    Kuder KJ; Załuski M; Schabikowski J; Latacz G; Olejarz-Maciej A; Jaśko P; Doroz-Płonka A; Brockmann A; Müller CE; Kieć-Kononowicz K
    ChemMedChem; 2020 May; 15(9):772-786. PubMed ID: 32162782
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Inhibition of monoamine oxidase by indole and benzofuran derivatives.
    Prins LH; Petzer JP; Malan SF
    Eur J Med Chem; 2010 Oct; 45(10):4458-66. PubMed ID: 20674099
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Fine molecular tuning at position 4 of 2H-chromen-2-one derivatives in the search of potent and selective monoamine oxidase B inhibitors.
    Pisani L; Catto M; Nicolotti O; Grossi G; Di Braccio M; Soto-Otero R; Mendez-Alvarez E; Stefanachi A; Gadaleta D; Carotti A
    Eur J Med Chem; 2013; 70():723-39. PubMed ID: 24231308
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Inhibition of monoamine oxidase A and B activities by imidazol(ine)/guanidine drugs, nature of the interaction and distinction from I2-imidazoline receptors in rat liver.
    Ozaita A; Olmos G; Boronat MA; Lizcano JM; Unzeta M; García-Sevilla JA
    Br J Pharmacol; 1997 Jul; 121(5):901-12. PubMed ID: 9222546
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 14.