344 related articles for article (PubMed ID: 23633488)
1. Hypoxia triggers hedgehog-mediated tumor-stromal interactions in pancreatic cancer.
Spivak-Kroizman TR; Hostetter G; Posner R; Aziz M; Hu C; Demeure MJ; Von Hoff D; Hingorani SR; Palculict TB; Izzo J; Kiriakova GM; Abdelmelek M; Bartholomeusz G; James BP; Powis G
Cancer Res; 2013 Jun; 73(11):3235-47. PubMed ID: 23633488
[TBL] [Abstract][Full Text] [Related]
2. Radiosensitization and stromal imaging response correlates for the HIF-1 inhibitor PX-478 given with or without chemotherapy in pancreatic cancer.
Schwartz DL; Bankson JA; Lemos R; Lai SY; Thittai AK; He Y; Hostetter G; Demeure MJ; Von Hoff DD; Powis G
Mol Cancer Ther; 2010 Jul; 9(7):2057-67. PubMed ID: 20587661
[TBL] [Abstract][Full Text] [Related]
3. Tumor-stromal cell interaction under hypoxia increases the invasiveness of pancreatic cancer cells through the hepatocyte growth factor/c-Met pathway.
Ide T; Kitajima Y; Miyoshi A; Ohtsuka T; Mitsuno M; Ohtaka K; Koga Y; Miyazaki K
Int J Cancer; 2006 Dec; 119(12):2750-9. PubMed ID: 16998831
[TBL] [Abstract][Full Text] [Related]
4. The hypoxic environment in tumor-stromal cells accelerates pancreatic cancer progression via the activation of paracrine hepatocyte growth factor/c-Met signaling.
Ide T; Kitajima Y; Miyoshi A; Ohtsuka T; Mitsuno M; Ohtaka K; Miyazaki K
Ann Surg Oncol; 2007 Sep; 14(9):2600-7. PubMed ID: 17534684
[TBL] [Abstract][Full Text] [Related]
5. Hypoxia-inducible factor-1 up-regulates the expression of Toll-like receptor 4 in pancreatic cancer cells under hypoxic conditions.
Fan P; Zhang JJ; Wang B; Wu HQ; Zhou SX; Wang CY; Zhang JH; Tian Y; Wu HS
Pancreatology; 2012; 12(2):170-8. PubMed ID: 22487528
[TBL] [Abstract][Full Text] [Related]
6. Hedgehog signaling regulates hypoxia induced epithelial to mesenchymal transition and invasion in pancreatic cancer cells via a ligand-independent manner.
Lei J; Ma J; Ma Q; Li X; Liu H; Xu Q; Duan W; Sun Q; Xu J; Wu Z; Wu E
Mol Cancer; 2013 Jun; 12():66. PubMed ID: 23786654
[TBL] [Abstract][Full Text] [Related]
7. The selective hypoxia inducible factor-1 inhibitor PX-478 provides in vivo radiosensitization through tumor stromal effects.
Schwartz DL; Powis G; Thitai-Kumar A; He Y; Bankson J; Williams R; Lemos R; Oh J; Volgin A; Soghomonyan S; Nishii R; Alauddin M; Mukhopadhay U; Peng Z; Bornmann W; Gelovani J
Mol Cancer Ther; 2009 Apr; 8(4):947-58. PubMed ID: 19372568
[TBL] [Abstract][Full Text] [Related]
8. Assessment of the stromal contribution to Sonic Hedgehog-dependent pancreatic adenocarcinoma.
Damhofer H; Medema JP; Veenstra VL; Badea L; Popescu I; Roelink H; Bijlsma MF
Mol Oncol; 2013 Dec; 7(6):1031-42. PubMed ID: 23998958
[TBL] [Abstract][Full Text] [Related]
9. Sonic hedgehog paracrine signaling activates stromal cells to promote perineural invasion in pancreatic cancer.
Li X; Wang Z; Ma Q; Xu Q; Liu H; Duan W; Lei J; Ma J; Wang X; Lv S; Han L; Li W; Guo J; Guo K; Zhang D; Wu E; Xie K
Clin Cancer Res; 2014 Aug; 20(16):4326-38. PubMed ID: 24947933
[TBL] [Abstract][Full Text] [Related]
10. LB-1 Exerts Antitumor Activity in Pancreatic Cancer by Inhibiting HIF-1α and Stat3 Signaling.
Niu F; Li Y; Lai FF; Ni L; Ji M; Jin J; Yang HZ; Wang C; Zhang DM; Chen XG
J Cell Physiol; 2015 Sep; 230(9):2212-23. PubMed ID: 25655308
[TBL] [Abstract][Full Text] [Related]
11. Hypoxia Accelerates Aggressiveness of Hepatocellular Carcinoma Cells Involving Oxidative Stress, Epithelial-Mesenchymal Transition and Non-Canonical Hedgehog Signaling.
Liu Z; Tu K; Wang Y; Yao B; Li Q; Wang L; Dou C; Liu Q; Zheng X
Cell Physiol Biochem; 2017; 44(5):1856-1868. PubMed ID: 29237157
[TBL] [Abstract][Full Text] [Related]
12. Identification of thioredoxin-interacting protein 1 as a hypoxia-inducible factor 1alpha-induced gene in pancreatic cancer.
Baker AF; Koh MY; Williams RR; James B; Wang H; Tate WR; Gallegos A; Von Hoff DD; Han H; Powis G
Pancreas; 2008 Mar; 36(2):178-86. PubMed ID: 18376310
[TBL] [Abstract][Full Text] [Related]
13. Autophagy in cancer associated fibroblasts promotes tumor cell survival: Role of hypoxia, HIF1 induction and NFκB activation in the tumor stromal microenvironment.
Martinez-Outschoorn UE; Trimmer C; Lin Z; Whitaker-Menezes D; Chiavarina B; Zhou J; Wang C; Pavlides S; Martinez-Cantarin MP; Capozza F; Witkiewicz AK; Flomenberg N; Howell A; Pestell RG; Caro J; Lisanti MP; Sotgia F
Cell Cycle; 2010 Sep; 9(17):3515-33. PubMed ID: 20855962
[TBL] [Abstract][Full Text] [Related]
14. Resveratrol inhibits hypoxia-driven ROS-induced invasive and migratory ability of pancreatic cancer cells via suppression of the Hedgehog signaling pathway.
Li W; Cao L; Chen X; Lei J; Ma Q
Oncol Rep; 2016 Mar; 35(3):1718-26. PubMed ID: 26707376
[TBL] [Abstract][Full Text] [Related]
15. Effects of the HIF-1α and NF-κB loop on epithelial-mesenchymal transition and chemoresistance induced by hypoxia in pancreatic cancer cells.
Cheng ZX; Wang DW; Liu T; Liu WX; Xia WB; Xu J; Zhang YH; Qu YK; Guo LQ; Ding L; Hou J; Zhong ZH
Oncol Rep; 2014 Apr; 31(4):1891-8. PubMed ID: 24535079
[TBL] [Abstract][Full Text] [Related]
16. A novel approach to cancer therapy using PX-478 as a HIF-1α inhibitor.
Lee K; Kim HM
Arch Pharm Res; 2011 Oct; 34(10):1583-5. PubMed ID: 22076756
[TBL] [Abstract][Full Text] [Related]
17. Knockdown of HIF-1α inhibits the proliferation and migration of outer root sheath cells exposed to hypoxia in vitro: An involvement of Shh pathway.
Zhang H; Nan W; Song X; Wang S; Si H; Li G
Life Sci; 2017 Dec; 191():82-89. PubMed ID: 29030089
[TBL] [Abstract][Full Text] [Related]
18. Canonical hedgehog signalling regulates hepatic stellate cell-mediated angiogenesis in liver fibrosis.
Zhang F; Hao M; Jin H; Yao Z; Lian N; Wu L; Shao J; Chen A; Zheng S
Br J Pharmacol; 2017 Mar; 174(5):409-423. PubMed ID: 28052321
[TBL] [Abstract][Full Text] [Related]
19. Constitutive expression of hypoxia-inducible factor-1alpha renders pancreatic cancer cells resistant to apoptosis induced by hypoxia and nutrient deprivation.
Akakura N; Kobayashi M; Horiuchi I; Suzuki A; Wang J; Chen J; Niizeki H; Kawamura Ki ; Hosokawa M; Asaka M
Cancer Res; 2001 Sep; 61(17):6548-54. PubMed ID: 11522653
[TBL] [Abstract][Full Text] [Related]
20. PX-478, an inhibitor of hypoxia-inducible factor-1alpha, enhances radiosensitivity of prostate carcinoma cells.
Palayoor ST; Mitchell JB; Cerna D; Degraff W; John-Aryankalayil M; Coleman CN
Int J Cancer; 2008 Nov; 123(10):2430-7. PubMed ID: 18729192
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]