BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

378 related articles for article (PubMed ID: 23637465)

  • 1. Ubiquitin conjugation triggers misfolded protein sequestration into quality control foci when Hsp70 chaperone levels are limiting.
    Shiber A; Breuer W; Brandeis M; Ravid T
    Mol Biol Cell; 2013 Jul; 24(13):2076-87. PubMed ID: 23637465
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The Type II Hsp40 Sis1 cooperates with Hsp70 and the E3 ligase Ubr1 to promote degradation of terminally misfolded cytosolic protein.
    Summers DW; Wolfe KJ; Ren HY; Cyr DM
    PLoS One; 2013; 8(1):e52099. PubMed ID: 23341891
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Hsp70-Hsp110 chaperones deliver ubiquitin-dependent and -independent substrates to the 26S proteasome for proteolysis in yeast.
    Kandasamy G; Andréasson C
    J Cell Sci; 2018 Mar; 131(6):. PubMed ID: 29507114
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The extent of Ssa1/Ssa2 Hsp70 chaperone involvement in nuclear protein quality control degradation varies with the substrate.
    Jones RD; Enam C; Ibarra R; Borror HR; Mostoller KE; Fredrickson EK; Lin J; Chuang E; March Z; Shorter J; Ravid T; Kleiger G; Gardner RG
    Mol Biol Cell; 2020 Feb; 31(3):221-233. PubMed ID: 31825716
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Degradation Signals for Ubiquitin-Proteasome Dependent Cytosolic Protein Quality Control (CytoQC) in Yeast.
    Maurer MJ; Spear ED; Yu AT; Lee EJ; Shahzad S; Michaelis S
    G3 (Bethesda); 2016 Jul; 6(7):1853-66. PubMed ID: 27172186
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The cytoplasmic Hsp70 chaperone machinery subjects misfolded and endoplasmic reticulum import-incompetent proteins to degradation via the ubiquitin-proteasome system.
    Park SH; Bolender N; Eisele F; Kostova Z; Takeuchi J; Coffino P; Wolf DH
    Mol Biol Cell; 2007 Jan; 18(1):153-65. PubMed ID: 17065559
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Hsp70 targets a cytoplasmic quality control substrate to the San1p ubiquitin ligase.
    Guerriero CJ; Weiberth KF; Brodsky JL
    J Biol Chem; 2013 Jun; 288(25):18506-20. PubMed ID: 23653356
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Spatial sequestration of misfolded proteins as an active chaperone-mediated process during heat stress.
    Boronat S; Cabrera M; Hidalgo E
    Curr Genet; 2021 Apr; 67(2):237-243. PubMed ID: 33386485
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Molecular chaperones of the Hsp70 family assist in the assembly of 20S proteasomes.
    Hammack LJ; Firestone K; Chang W; Kusmierczyk AR
    Biochem Biophys Res Commun; 2017 Apr; 486(2):438-443. PubMed ID: 28322792
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Direct interactions between molecular chaperones heat-shock protein (Hsp) 70 and Hsp40: yeast Hsp70 Ssa1 binds the extreme C-terminal region of yeast Hsp40 Sis1.
    Qian X; Hou W; Zhengang L; Sha B
    Biochem J; 2002 Jan; 361(Pt 1):27-34. PubMed ID: 11743879
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The requirements of yeast Hsp70 of SSA family for the ubiquitin-dependent degradation of short-lived and abnormal proteins.
    Lee do H; Sherman MY; Goldberg AL
    Biochem Biophys Res Commun; 2016 Jun; 475(1):100-6. PubMed ID: 27178214
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Search for novel stress-responsive protein components using a yeast mutant lacking two cytosolic Hsp70 genes, SSA1 and SSA2.
    Matsumoto R; Rakwal R; Agrawal GK; Jung YH; Jwa NS; Yonekura M; Iwahashi H; Akama K
    Mol Cells; 2006 Jun; 21(3):381-8. PubMed ID: 16819301
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Class-specific interactions between Sis1 J-domain protein and Hsp70 chaperone potentiate disaggregation of misfolded proteins.
    Wyszkowski H; Janta A; Sztangierska W; Obuchowski I; Chamera T; Kłosowska A; Liberek K
    Proc Natl Acad Sci U S A; 2021 Dec; 118(49):. PubMed ID: 34873058
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The stress response against denatured proteins in the deletion of cytosolic chaperones SSA1/2 is different from heat-shock response in Saccharomyces cerevisiae.
    Matsumoto R; Akama K; Rakwal R; Iwahashi H
    BMC Genomics; 2005 Oct; 6():141. PubMed ID: 16209719
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Hsp40 molecules that target to the ubiquitin-proteasome system decrease inclusion formation in models of polyglutamine disease.
    Howarth JL; Kelly S; Keasey MP; Glover CP; Lee YB; Mitrophanous K; Chapple JP; Gallo JM; Cheetham ME; Uney JB
    Mol Ther; 2007 Jun; 15(6):1100-5. PubMed ID: 17426712
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Hsp70 nucleotide exchange factor Fes1 is essential for ubiquitin-dependent degradation of misfolded cytosolic proteins.
    Gowda NK; Kandasamy G; Froehlich MS; Dohmen RJ; Andréasson C
    Proc Natl Acad Sci U S A; 2013 Apr; 110(15):5975-80. PubMed ID: 23530227
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Quality control of a cytoplasmic protein complex: chaperone motors and the ubiquitin-proteasome system govern the fate of orphan fatty acid synthase subunit Fas2 of yeast.
    Scazzari M; Amm I; Wolf DH
    J Biol Chem; 2015 Feb; 290(8):4677-4687. PubMed ID: 25564609
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Chaperone-Mediated Protein Disaggregation Triggers Proteolytic Clearance of Intra-nuclear Protein Inclusions.
    den Brave F; Cairo LV; Jagadeesan C; Ruger-Herreros C; Mogk A; Bukau B; Jentsch S
    Cell Rep; 2020 Jun; 31(9):107680. PubMed ID: 32492414
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Functional rescue of mutant human cystathionine beta-synthase by manipulation of Hsp26 and Hsp70 levels in Saccharomyces cerevisiae.
    Singh LR; Kruger WD
    J Biol Chem; 2009 Feb; 284(7):4238-45. PubMed ID: 19074437
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Mutations in the Yeast Hsp70, Ssa1, at P417 Alter ATP Cycling, Interdomain Coupling, and Specific Chaperone Functions.
    Needham PG; Patel HJ; Chiosis G; Thibodeau PH; Brodsky JL
    J Mol Biol; 2015 Sep; 427(18):2948-65. PubMed ID: 25913688
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 19.