BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

221 related articles for article (PubMed ID: 23640880)

  • 1. Propofol binding to the resting state of the gloeobacter violaceus ligand-gated ion channel (GLIC) induces structural changes in the inter- and intrasubunit transmembrane domain (TMD) cavities.
    Ghosh B; Satyshur KA; Czajkowski C
    J Biol Chem; 2013 Jun; 288(24):17420-31. PubMed ID: 23640880
    [TBL] [Abstract][Full Text] [Related]  

  • 2. A chimeric prokaryotic-eukaryotic pentameric ligand gated ion channel reveals interactions between the extracellular and transmembrane domains shape neurosteroid modulation.
    Ghosh B; Tsao TW; Czajkowski C
    Neuropharmacology; 2017 Oct; 125():343-352. PubMed ID: 28803966
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Site-directed spin labeling reveals pentameric ligand-gated ion channel gating motions.
    Dellisanti CD; Ghosh B; Hanson SM; Raspanti JM; Grant VA; Diarra GM; Schuh AM; Satyshur K; Klug CS; Czajkowski C
    PLoS Biol; 2013 Nov; 11(11):e1001714. PubMed ID: 24260024
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Anesthetic binding in a pentameric ligand-gated ion channel: GLIC.
    Chen Q; Cheng MH; Xu Y; Tang P
    Biophys J; 2010 Sep; 99(6):1801-9. PubMed ID: 20858424
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Mapping two neurosteroid-modulatory sites in the prototypic pentameric ligand-gated ion channel GLIC.
    Cheng WWL; Chen ZW; Bracamontes JR; Budelier MM; Krishnan K; Shin DJ; Wang C; Jiang X; Covey DF; Akk G; Evers AS
    J Biol Chem; 2018 Feb; 293(8):3013-3027. PubMed ID: 29301936
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Inhibition versus potentiation of ligand-gated ion channels can be altered by a single mutation that moves ligands between intra- and intersubunit sites.
    Brömstrup T; Howard RJ; Trudell JR; Harris RA; Lindahl E
    Structure; 2013 Aug; 21(8):1307-16. PubMed ID: 23891290
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Allosteric potentiation of a ligand-gated ion channel is mediated by access to a deep membrane-facing cavity.
    Heusser SA; Lycksell M; Wang X; McComas SE; Howard RJ; Lindahl E
    Proc Natl Acad Sci U S A; 2018 Oct; 115(42):10672-10677. PubMed ID: 30275330
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Electrostatics, proton sensor, and networks governing the gating transition in GLIC, a proton-gated pentameric ion channel.
    Hu H; Ataka K; Menny A; Fourati Z; Sauguet L; Corringer PJ; Koehl P; Heberle J; Delarue M
    Proc Natl Acad Sci U S A; 2018 Dec; 115(52):E12172-E12181. PubMed ID: 30541892
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Structural basis for allosteric coupling at the membrane-protein interface in Gloeobacter violaceus ligand-gated ion channel (GLIC).
    Velisetty P; Chalamalasetti SV; Chakrapani S
    J Biol Chem; 2014 Jan; 289(5):3013-25. PubMed ID: 24338475
    [TBL] [Abstract][Full Text] [Related]  

  • 10. X-ray structures of general anaesthetics bound to a pentameric ligand-gated ion channel.
    Nury H; Van Renterghem C; Weng Y; Tran A; Baaden M; Dufresne V; Changeux JP; Sonner JM; Delarue M; Corringer PJ
    Nature; 2011 Jan; 469(7330):428-31. PubMed ID: 21248852
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Photoaffinity labeling the propofol binding site in GLIC.
    Chiara DC; Gill JF; Chen Q; Tillman T; Dailey WP; Eckenhoff RG; Xu Y; Tang P; Cohen JB
    Biochemistry; 2014 Jan; 53(1):135-42. PubMed ID: 24341978
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Common Anesthetic-binding Site for Inhibition of Pentameric Ligand-gated Ion Channels.
    Kinde MN; Bu W; Chen Q; Xu Y; Eckenhoff RG; Tang P
    Anesthesiology; 2016 Mar; 124(3):664-73. PubMed ID: 26756520
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Structure of the pentameric ligand-gated ion channel GLIC bound with anesthetic ketamine.
    Pan J; Chen Q; Willenbring D; Mowrey D; Kong XP; Cohen A; Divito CB; Xu Y; Tang P
    Structure; 2012 Sep; 20(9):1463-9. PubMed ID: 22958642
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Conformational transitions underlying pore opening and desensitization in membrane-embedded Gloeobacter violaceus ligand-gated ion channel (GLIC).
    Velisetty P; Chalamalasetti SV; Chakrapani S
    J Biol Chem; 2012 Oct; 287(44):36864-72. PubMed ID: 22977232
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Functional prokaryotic-eukaryotic chimera from the pentameric ligand-gated ion channel family.
    Duret G; Van Renterghem C; Weng Y; Prevost M; Moraga-Cid G; Huon C; Sonner JM; Corringer PJ
    Proc Natl Acad Sci U S A; 2011 Jul; 108(29):12143-8. PubMed ID: 21730130
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Structural Basis for a Bimodal Allosteric Mechanism of General Anesthetic Modulation in Pentameric Ligand-Gated Ion Channels.
    Fourati Z; Howard RJ; Heusser SA; Hu H; Ruza RR; Sauguet L; Lindahl E; Delarue M
    Cell Rep; 2018 Apr; 23(4):993-1004. PubMed ID: 29694907
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Reversal of ion-charge selectivity renders the pentameric ligand-gated ion channel GLIC insensitive to anaesthetics.
    Tillman T; Cheng MH; Chen Q; Tang P; Xu Y
    Biochem J; 2013 Jan; 449(1):61-8. PubMed ID: 22978431
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Multisite binding of a general anesthetic to the prokaryotic pentameric Erwinia chrysanthemi ligand-gated ion channel (ELIC).
    Spurny R; Billen B; Howard RJ; Brams M; Debaveye S; Price KL; Weston DA; Strelkov SV; Tytgat J; Bertrand S; Bertrand D; Lummis SCR; Ulens C
    J Biol Chem; 2013 Mar; 288(12):8355-8364. PubMed ID: 23364792
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Ketamine Inhibition of the Pentameric Ligand-Gated Ion Channel GLIC.
    Ion BF; Wells MM; Chen Q; Xu Y; Tang P
    Biophys J; 2017 Aug; 113(3):605-612. PubMed ID: 28793215
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Opposing effects of the anesthetic propofol at pentameric ligand-gated ion channels mediated by a common site.
    Lynagh T; Laube B
    J Neurosci; 2014 Feb; 34(6):2155-9. PubMed ID: 24501356
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.